STE_PAK5 (Serine/threonine-protein kinase PAK 5)

Total number of chains: 5
Active chains: 4
Uniprot: PAK5_HUMAN
Kinase Domain Residues: 449 - 700
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-Q9P286-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q9P286-K1A 441 708 719.0 No_ligand No_ligand Active DFGin 6.004 13.442 BLAminus -129.77, -175.07 63.13, 52.05 -75.54, 6.19 303.07, 103.68 -59.01, -34.74 in-in in 7.609 Saltbr-in 2.712 HRD-in -70.11, -50.47 65.78, 8.67 in-in-in SNCiii in-in ActLoopNT-in 2.792 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.89, 166.12 APE9-dihe-na 109.42, 172.62 APE8-dihe-in -76.54, 132.8 APE8-rot-in 304.61 APE67-dihe-inflip 74.32, -45.03 -49.87, 165.88 APE12-dist-in 9.082 APE11-dist-in 11.594 APE10-dist-in 5.636 APE9-dist-in 3.251 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[449, 700]] 1.0 AF-Q9P286-K1 STE_PAK5_HUMAN STE 4.3e-89 304.2 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
AF-Q9P286-K3A 441 708 719.0 No_ligand No_ligand Active DFGin 6.262 14.249 BLAminus -136.89, -172.09 63.87, 42.97 -70.3, 3.31 293.18, 91.89 -56.06, -30.69 in-in in 6.935 Saltbr-in 2.706 HRD-in -72.56, -46.79 67.56, 1.69 in-in-in SNCiii in-in ActLoopNT-in 2.821 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.81, 146.53 APE9-dihe-na 121.18, 175.76 APE8-dihe-in -89.03, 128.84 APE8-rot-in 301.05 APE67-dihe-in -75.65, -20.5 -45.44, -43.26 APE12-dist-in 9.012 APE11-dist-in 11.454 APE10-dist-in 5.729 APE9-dist-in 3.049 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[449, 700]] 1.0 AF-Q9P286-K3 STE_PAK5_HUMAN STE 4.3e-89 304.2 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
8C12AAA 426 717 719.0 No_ligand No_ligand Active DFGin 7.443 14.738 BLAminus -130.39, -175.88 62.56, 62.57 -89.05, 13.56 281.14, 76.23 -54.69, -32.83 in-in in 8.768 Saltbr-in 2.706 HRD-in -73.87, -52.79 77.78, 6.37 in-in-in SNCiii in-in ActLoopNT-in 2.868 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.99, 155.01 APE9-dihe-na 126.14, -158.85 APE8-dihe-in -125.7, 122.59 APE8-rot-in 306.85 APE67-dihe-in -69.44, -21.48 -34.95, -54.42 APE12-dist-in 8.443 APE11-dist-in 10.982 APE10-dist-in 5.202 APE9-dist-in 3.312 None SEP602 SEP602 XRAY 1.549 0.199 0.234 AAA 295 292 0 0 0 0 [[449, 700]] 1.0 8c12 STE_PAK5_HUMAN STE 6.1e-89 303.7 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
2F57B 425 718 719.0 23D:60001 Type1 Active DFGin 7.147 15.159 BLAminus -130.03, -174.06 58.73, 69.39 -94.87, 19.1 283.86, 78.72 -55.48, -32.98 in-in in 8.325 Saltbr-in 2.739 HRD-in -71.01, -50.04 72.02, 1.25 in-in-in SNCiii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.95, 140.47 APE9-dihe-na 141.83, -168.91 APE8-dihe-in -111.96, 119.79 APE8-rot-in 303.61 APE67-dihe-in -66.26, -20.96 -34.19, -58.65 APE12-dist-in 8.913 APE11-dist-in 11.471 APE10-dist-in 5.682 APE9-dist-in 3.406 None SEP602 SEP602 XRAY 1.8 0.155 0.185 B 317 294 0 0 0 0 [[449, 700]] 1.0 2f57 STE_PAK5_HUMAN STE 7.8e-89 303.4 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
2F57A 425 715 719.0 No_ligand No_ligand Inactive DFGin 7.516 15.961 BLAminus -132.24, -179.07 54.47, 81.52 -94.01, 25.23 285.2, 72.28 -59.96, -25.16 out-none out 11.079 Saltbr-none 999.0 HRD-in -72.74, -45.03 70.4, -1.95 none-in-in SNCnii in-in ActLoopNT-in 2.774 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.46, 142.22 APE9-dihe-na 144.01, -171.13 APE8-dihe-in -106.28, 111.65 APE8-rot-in 305.86 APE67-dihe-in -64.34, -20.12 -23.16, -62.0 APE12-dist-in 9.075 APE11-dist-in 11.453 APE10-dist-in 5.611 APE9-dist-in 3.752 None SEP602 SEP602 XRAY 1.8 0.155 0.185 A 317 291 0 0 0 0 [[449, 700]] 1.0 2f57 STE_PAK5_HUMAN STE 7.8e-89 303.4 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5

STE_PAK5 (Serine/threonine-protein kinase PAK 5)

Total number of chains: 5
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-Q9P286-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
PAK5_HUMAN AF-Q9P286-K1A Q9P286 441 708 719.0 No_ligand No_ligand Active DFGin 6.004 13.442 BLAminus -129.77, -175.07 63.13, 52.05 -75.54, 6.19 303.07, 103.68 -59.01, -34.74 in-in in 7.609 Saltbr-in 2.712 HRD-in -70.11, -50.47 65.78, 8.67 in-in-in SNCiii in-in ActLoopNT-in 2.792 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.89, 166.12 APE9-dihe-na 109.42, 172.62 APE8-dihe-in -76.54, 132.8 APE8-rot-in 304.61 APE67-dihe-inflip 74.32, -45.03 -49.87, 165.88 APE12-dist-in 9.082 APE11-dist-in 11.594 APE10-dist-in 5.636 APE9-dist-in 3.251 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[449, 700]] 1.0 AF-Q9P286-K1 Homo sapiens STE_PAK5_HUMAN STE 4.3e-89 304.2 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
PAK5_HUMAN AF-Q9P286-K3A Q9P286 441 708 719.0 No_ligand No_ligand Active DFGin 6.262 14.249 BLAminus -136.89, -172.09 63.87, 42.97 -70.3, 3.31 293.18, 91.89 -56.06, -30.69 in-in in 6.935 Saltbr-in 2.706 HRD-in -72.56, -46.79 67.56, 1.69 in-in-in SNCiii in-in ActLoopNT-in 2.821 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.81, 146.53 APE9-dihe-na 121.18, 175.76 APE8-dihe-in -89.03, 128.84 APE8-rot-in 301.05 APE67-dihe-in -75.65, -20.5 -45.44, -43.26 APE12-dist-in 9.012 APE11-dist-in 11.454 APE10-dist-in 5.729 APE9-dist-in 3.049 None None None AF2 -1.0 1.0 1.0 A 268 268 0 0 0 0 [[449, 700]] 1.0 AF-Q9P286-K3 Homo sapiens STE_PAK5_HUMAN STE 4.3e-89 304.2 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
PAK5_HUMAN 8C12AAA Q9P286 426 717 719.0 No_ligand No_ligand Active DFGin 7.443 14.738 BLAminus -130.39, -175.88 62.56, 62.57 -89.05, 13.56 281.14, 76.23 -54.69, -32.83 in-in in 8.768 Saltbr-in 2.706 HRD-in -73.87, -52.79 77.78, 6.37 in-in-in SNCiii in-in ActLoopNT-in 2.868 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.99, 155.01 APE9-dihe-na 126.14, -158.85 APE8-dihe-in -125.7, 122.59 APE8-rot-in 306.85 APE67-dihe-in -69.44, -21.48 -34.95, -54.42 APE12-dist-in 8.443 APE11-dist-in 10.982 APE10-dist-in 5.202 APE9-dist-in 3.312 None SEP602 SEP602 XRAY 1.549 0.199 0.234 AAA 295 292 0 0 0 0 [[449, 700]] 1.0 8c12 Homo sapiens STE_PAK5_HUMAN STE 6.1e-89 303.7 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
PAK5_HUMAN 2F57B Q9P286 425 718 719.0 23D:60001 Type1 Active DFGin 7.147 15.159 BLAminus -130.03, -174.06 58.73, 69.39 -94.87, 19.1 283.86, 78.72 -55.48, -32.98 in-in in 8.325 Saltbr-in 2.739 HRD-in -71.01, -50.04 72.02, 1.25 in-in-in SNCiii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.95, 140.47 APE9-dihe-na 141.83, -168.91 APE8-dihe-in -111.96, 119.79 APE8-rot-in 303.61 APE67-dihe-in -66.26, -20.96 -34.19, -58.65 APE12-dist-in 8.913 APE11-dist-in 11.471 APE10-dist-in 5.682 APE9-dist-in 3.406 None SEP602 SEP602 XRAY 1.8 0.155 0.185 B 317 294 0 0 0 0 [[449, 700]] 1.0 2f57 Homo sapiens STE_PAK5_HUMAN STE 7.8e-89 303.4 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5
PAK5_HUMAN 2F57A Q9P286 425 715 719.0 No_ligand No_ligand Inactive DFGin 7.516 15.961 BLAminus -132.24, -179.07 54.47, 81.52 -94.01, 25.23 285.2, 72.28 -59.96, -25.16 out-none out 11.079 Saltbr-none 999.0 HRD-in -72.74, -45.03 70.4, -1.95 none-in-in SNCnii in-in ActLoopNT-in 2.774 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.46, 142.22 APE9-dihe-na 144.01, -171.13 APE8-dihe-in -106.28, 111.65 APE8-rot-in 305.86 APE67-dihe-in -64.34, -20.12 -23.16, -62.0 APE12-dist-in 9.075 APE11-dist-in 11.453 APE10-dist-in 5.611 APE9-dist-in 3.752 None SEP602 SEP602 XRAY 1.8 0.155 0.185 A 317 291 0 0 0 0 [[449, 700]] 1.0 2f57 Homo sapiens STE_PAK5_HUMAN STE 7.8e-89 303.4 5 257 253 585 586 587 589 591 478 494 498 565 567 566 568 625 613 608 607 606 605 604 603 602 524 Serine/threonine-protein kinase PAK 5

STE_PAK5 (Serine/threonine-protein kinase PAK 5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name