CAMK_MYLK2 (Myosin light chain kinase 2, skeletal/cardiac muscle)

Total number of chains: 2
Active chains: 2
Uniprot: MYLK2_HUMAN
Kinase Domain Residues: 283 - 540
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9H1R3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYLK2 AF-Q9H1R3-K1A Q9H1R3 275 548 596.0 No_ligand No_ligand Active DFGin 6.1705 13.5241 BLAminus -125.61, 177.06 58.14, 72.22 -80.86, 16.84 300.19, 104.44 -60.25, -29.25 in-in in 9.1006 Saltbr-in 2.7357 HRD-in -77.26, -49.24 63.47, 0.97 in-in-in SNCiii in-in ActLoopNT-in 2.8215 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.24, 157.42 APE9-dihe-na 132.27, 177.77 APE8-dihe-in -83.65, 124.86 APE8-rot-in 299.0 APE67-dihe-in -57.47, -30.01 -46.9, -45.42 APE12-dist-in 8.2526 APE11-dist-in 11.8594 APE10-dist-in 6.8124 APE9-dist-in 4.5403 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[285, 540]] 1.0 AF-Q9H1R3-K1 CAMK_MYLK2_HUMAN CAMK 1.8e-84 289.1 4.0 256.0 253.0 425 426 427 429 431 314 330 334 403 405 404 406.0 464 452 447 446 445 444 443 442 441 360 Myosin light chain kinase 2, skeletal/cardiac muscle
MYLK2 AF-Q9H1R3-K3A Q9H1R3 275 548 596.0 No_ligand No_ligand Active DFGin 5.8539 13.3853 BLAminus -127.09, 178.7 58.07, 69.72 -79.89, 14.62 303.71, 102.01 -62.29, -28.3 in-in in 8.8262 Saltbr-in 2.7032 HRD-in -81.15, -47.46 63.41, 14.41 in-in-in SNCiii in-in ActLoopNT-in 2.9012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.14, 159.93 APE9-dihe-na 137.17, -175.13 APE8-dihe-in -88.93, 123.39 APE8-rot-in 303.83 APE67-dihe-in -60.01, -31.82 -46.13, -48.61 APE12-dist-in 8.1995 APE11-dist-in 11.5632 APE10-dist-in 6.7241 APE9-dist-in 3.9896 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[285, 540]] 1.0 AF-Q9H1R3-K3 CAMK_MYLK2_HUMAN CAMK 1.8e-84 289.1 4.0 256.0 253.0 425 426 427 429 431 314 330 334 403 405 404 406.0 464 452 447 446 445 444 443 442 441 360 Myosin light chain kinase 2, skeletal/cardiac muscle

CAMK_MYLK2 (Myosin light chain kinase 2, skeletal/cardiac muscle)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9H1R3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MYLK2 MYLK2_HUMAN AF-Q9H1R3-K1A Q9H1R3 275 548 596.0 No_ligand No_ligand Active DFGin 6.1705 13.5241 BLAminus -125.61, 177.06 58.14, 72.22 -80.86, 16.84 300.19, 104.44 -60.25, -29.25 in-in in 9.1006 Saltbr-in 2.7357 HRD-in -77.26, -49.24 63.47, 0.97 in-in-in SNCiii in-in ActLoopNT-in 2.8215 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.24, 157.42 APE9-dihe-na 132.27, 177.77 APE8-dihe-in -83.65, 124.86 APE8-rot-in 299.0 APE67-dihe-in -57.47, -30.01 -46.9, -45.42 APE12-dist-in 8.2526 APE11-dist-in 11.8594 APE10-dist-in 6.8124 APE9-dist-in 4.5403 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[285, 540]] 1.0 AF-Q9H1R3-K1 Homo sapiens CAMK_MYLK2_HUMAN CAMK 1.8e-84 289.1 4.0 256.0 253.0 425 426 427 429 431 314 330 334 403 405 404 406.0 464 452 447 446 445 444 443 442 441 360 Myosin light chain kinase 2, skeletal/cardiac muscle
MYLK2 MYLK2_HUMAN AF-Q9H1R3-K3A Q9H1R3 275 548 596.0 No_ligand No_ligand Active DFGin 5.8539 13.3853 BLAminus -127.09, 178.7 58.07, 69.72 -79.89, 14.62 303.71, 102.01 -62.29, -28.3 in-in in 8.8262 Saltbr-in 2.7032 HRD-in -81.15, -47.46 63.41, 14.41 in-in-in SNCiii in-in ActLoopNT-in 2.9012 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.14, 159.93 APE9-dihe-na 137.17, -175.13 APE8-dihe-in -88.93, 123.39 APE8-rot-in 303.83 APE67-dihe-in -60.01, -31.82 -46.13, -48.61 APE12-dist-in 8.1995 APE11-dist-in 11.5632 APE10-dist-in 6.7241 APE9-dist-in 3.9896 None None None AF2 -1.0 1.0 1.0 A 274.0 274.0 0 27 27 0 [[285, 540]] 1.0 AF-Q9H1R3-K3 Homo sapiens CAMK_MYLK2_HUMAN CAMK 1.8e-84 289.1 4.0 256.0 253.0 425 426 427 429 431 314 330 334 403 405 404 406.0 464 452 447 446 445 444 443 442 441 360 Myosin light chain kinase 2, skeletal/cardiac muscle

CAMK_MYLK2 (Myosin light chain kinase 2, skeletal/cardiac muscle)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name