CMGC_MOK (MAPK/MAK/MRK overlapping kinase)

Total number of chains: 2
Active chains: 2
Uniprot: MOK_HUMAN
Kinase Domain Residues: 4 - 285
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9UQ07-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MOK AF-Q9UQ07-K1A Q9UQ07 1 293 419.0 No_ligand No_ligand Active DFGin 6.2 14.587 BLAminus -123.9, -177.45 53.69, 76.37 -85.85, 16.88 286.38, 74.19 -57.15, -33.84 in-in in 8.7586 Saltbr-in 2.7548 HRD-in -76.61, -45.42 66.71, -2.84 in-in-in SNCiii in-in ActLoopNT-in 2.9366 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.99, 157.89 APE9-dihe-na 57.66, 138.31 APE8-dihe-in -60.08, 130.11 APE8-rot-in 301.28 APE67-dihe-in -64.06, -22.55 -42.54, -45.02 APE12-dist-in 12.8989 APE11-dist-in 10.6828 APE10-dist-in 6.9918 APE9-dist-in 3.0357 None None None AF2 -1.0 1.0 1.0 A 293.0 293.0 0 27 27 0 [[4, 285]] 1.0 AF-Q9UQ07-K1 CMGC_MOK_HUMAN CMGC 1.5e-74 258.2 1.0 301.0 301.0 144 145 146 148 150 33 50 54 125 127 126 128.0 184 171 166 165 164 163 162 161 160 83 MAPK/MAK/MRK overlapping kinase
MOK AF-Q9UQ07-K3A Q9UQ07 1 293 419.0 No_ligand No_ligand Active DFGin 6.1134 14.4499 BLAminus -124.78, -169.47 56.05, 62.98 -76.96, 13.88 289.75, 83.05 -55.59, -35.4 in-in in 8.6526 Saltbr-in 2.6916 HRD-in -81.53, -45.85 68.45, -0.13 in-in-in SNCiii in-in ActLoopNT-in 2.9062 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.03, 163.25 APE9-dihe-na 60.72, 147.56 APE8-dihe-in -65.07, 132.63 APE8-rot-in 301.36 APE67-dihe-in -64.82, -17.3 -49.12, -48.64 APE12-dist-in 13.3844 APE11-dist-in 11.6032 APE10-dist-in 7.1462 APE9-dist-in 3.3062 None None None AF2 -1.0 1.0 1.0 A 293.0 293.0 0 27 27 0 [[4, 285]] 1.0 AF-Q9UQ07-K3 CMGC_MOK_HUMAN CMGC 1.5e-74 258.2 1.0 301.0 301.0 144 145 146 148 150 33 50 54 125 127 126 128.0 184 171 166 165 164 163 162 161 160 83 MAPK/MAK/MRK overlapping kinase

CMGC_MOK (MAPK/MAK/MRK overlapping kinase)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9UQ07-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MOK MOK_HUMAN AF-Q9UQ07-K1A Q9UQ07 1 293 419.0 No_ligand No_ligand Active DFGin 6.2 14.587 BLAminus -123.9, -177.45 53.69, 76.37 -85.85, 16.88 286.38, 74.19 -57.15, -33.84 in-in in 8.7586 Saltbr-in 2.7548 HRD-in -76.61, -45.42 66.71, -2.84 in-in-in SNCiii in-in ActLoopNT-in 2.9366 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.99, 157.89 APE9-dihe-na 57.66, 138.31 APE8-dihe-in -60.08, 130.11 APE8-rot-in 301.28 APE67-dihe-in -64.06, -22.55 -42.54, -45.02 APE12-dist-in 12.8989 APE11-dist-in 10.6828 APE10-dist-in 6.9918 APE9-dist-in 3.0357 None None None AF2 -1.0 1.0 1.0 A 293.0 293.0 0 27 27 0 [[4, 285]] 1.0 AF-Q9UQ07-K1 Homo sapiens CMGC_MOK_HUMAN CMGC 1.5e-74 258.2 1.0 301.0 301.0 144 145 146 148 150 33 50 54 125 127 126 128.0 184 171 166 165 164 163 162 161 160 83 MAPK/MAK/MRK overlapping kinase
MOK MOK_HUMAN AF-Q9UQ07-K3A Q9UQ07 1 293 419.0 No_ligand No_ligand Active DFGin 6.1134 14.4499 BLAminus -124.78, -169.47 56.05, 62.98 -76.96, 13.88 289.75, 83.05 -55.59, -35.4 in-in in 8.6526 Saltbr-in 2.6916 HRD-in -81.53, -45.85 68.45, -0.13 in-in-in SNCiii in-in ActLoopNT-in 2.9062 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.03, 163.25 APE9-dihe-na 60.72, 147.56 APE8-dihe-in -65.07, 132.63 APE8-rot-in 301.36 APE67-dihe-in -64.82, -17.3 -49.12, -48.64 APE12-dist-in 13.3844 APE11-dist-in 11.6032 APE10-dist-in 7.1462 APE9-dist-in 3.3062 None None None AF2 -1.0 1.0 1.0 A 293.0 293.0 0 27 27 0 [[4, 285]] 1.0 AF-Q9UQ07-K3 Homo sapiens CMGC_MOK_HUMAN CMGC 1.5e-74 258.2 1.0 301.0 301.0 144 145 146 148 150 33 50 54 125 127 126 128.0 184 171 166 165 164 163 162 161 160 83 MAPK/MAK/MRK overlapping kinase

CMGC_MOK (MAPK/MAK/MRK overlapping kinase)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name