CMGC_MAPK4 (Mitogen-activated protein kinase 4)

Total number of chains: 2
Active chains: 2
Uniprot: MK04_HUMAN
Kinase Domain Residues: 20 - 312
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P31152-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK4 AF-P31152-K1A P31152 12 320 587.0 No_ligand No_ligand Active DFGin 6.3371 14.3613 BLAminus -140.3, -171.17 54.64, 76.19 -85.1, 16.82 289.94, 82.39 -59.9, -26.76 in-in in 9.2063 Saltbr-in 2.6331 HRD-in -69.77, -46.05 69.01, -12.01 in-in-in SNCiii in-in ActLoopNT-in 2.7839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.64, 61.54 APE9-dihe-na -98.96, 155.06 APE8-dihe-in -56.1, 119.55 APE8-rot-in 305.0 APE67-dihe-in -69.58, -20.7 -46.48, -45.39 APE12-dist-in 11.4516 APE11-dist-in 8.8669 APE10-dist-in 7.6058 APE9-dist-in 4.1404 None None None AF2 -1.0 1.0 1.0 A 309.0 309.0 0 31 31 0 [[20, 312]] 1.0 AF-P31152-K1 CMGC_MAPK4_HUMAN CMGC 2.6e-73 253.2 4.0 301.0 298.0 167 168 169 171 173 49 65 69 146 148 147 149.0 211 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase 4
MAPK4 AF-P31152-K3A P31152 12 320 587.0 No_ligand No_ligand Active DFGin 6.3598 14.3037 BLAminus -139.34, -171.41 55.64, 66.74 -75.91, 17.21 290.48, 84.41 -59.95, -25.29 in-in in 9.1618 Saltbr-in 2.689 HRD-in -72.48, -45.78 67.09, -10.32 in-in-in SNCiii in-in ActLoopNT-in 2.8174 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.11, -6.61 APE9-dihe-na -82.69, 139.46 APE8-dihe-in -57.48, 122.03 APE8-rot-in 291.99 APE67-dihe-in -65.98, -17.25 -49.34, -54.23 APE12-dist-in 12.1083 APE11-dist-in 10.6017 APE10-dist-in 6.253 APE9-dist-in 4.194 None None None AF2 -1.0 1.0 1.0 A 309.0 309.0 0 31 31 0 [[20, 312]] 1.0 AF-P31152-K3 CMGC_MAPK4_HUMAN CMGC 2.6e-73 253.2 4.0 301.0 298.0 167 168 169 171 173 49 65 69 146 148 147 149.0 211 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase 4

CMGC_MAPK4 (Mitogen-activated protein kinase 4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P31152-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK4 MK04_HUMAN AF-P31152-K1A P31152 12 320 587.0 No_ligand No_ligand Active DFGin 6.3371 14.3613 BLAminus -140.3, -171.17 54.64, 76.19 -85.1, 16.82 289.94, 82.39 -59.9, -26.76 in-in in 9.2063 Saltbr-in 2.6331 HRD-in -69.77, -46.05 69.01, -12.01 in-in-in SNCiii in-in ActLoopNT-in 2.7839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.64, 61.54 APE9-dihe-na -98.96, 155.06 APE8-dihe-in -56.1, 119.55 APE8-rot-in 305.0 APE67-dihe-in -69.58, -20.7 -46.48, -45.39 APE12-dist-in 11.4516 APE11-dist-in 8.8669 APE10-dist-in 7.6058 APE9-dist-in 4.1404 None None None AF2 -1.0 1.0 1.0 A 309.0 309.0 0 31 31 0 [[20, 312]] 1.0 AF-P31152-K1 Homo sapiens CMGC_MAPK4_HUMAN CMGC 2.6e-73 253.2 4.0 301.0 298.0 167 168 169 171 173 49 65 69 146 148 147 149.0 211 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase 4
MAPK4 MK04_HUMAN AF-P31152-K3A P31152 12 320 587.0 No_ligand No_ligand Active DFGin 6.3598 14.3037 BLAminus -139.34, -171.41 55.64, 66.74 -75.91, 17.21 290.48, 84.41 -59.95, -25.29 in-in in 9.1618 Saltbr-in 2.689 HRD-in -72.48, -45.78 67.09, -10.32 in-in-in SNCiii in-in ActLoopNT-in 2.8174 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.11, -6.61 APE9-dihe-na -82.69, 139.46 APE8-dihe-in -57.48, 122.03 APE8-rot-in 291.99 APE67-dihe-in -65.98, -17.25 -49.34, -54.23 APE12-dist-in 12.1083 APE11-dist-in 10.6017 APE10-dist-in 6.253 APE9-dist-in 4.194 None None None AF2 -1.0 1.0 1.0 A 309.0 309.0 0 31 31 0 [[20, 312]] 1.0 AF-P31152-K3 Homo sapiens CMGC_MAPK4_HUMAN CMGC 2.6e-73 253.2 4.0 301.0 298.0 167 168 169 171 173 49 65 69 146 148 147 149.0 211 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase 4

CMGC_MAPK4 (Mitogen-activated protein kinase 4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name