CMGC_MAK (Serine/threonine-protein kinase MAK)

Total number of chains: 2
Active chains: 2
Uniprot: MAK_HUMAN
Kinase Domain Residues: 4 - 284
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P20794-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAK AF-P20794-K1A P20794 1 292 623.0 No_ligand No_ligand Active DFGin 6.4396 15.0129 BLAminus -134.23, 177.07 57.26, 69.59 -81.21, 18.58 288.24, 75.28 -58.77, -33.04 in-in in 8.9238 Saltbr-in 2.7971 HRD-in -78.15, -45.64 65.48, 7.28 in-in-in SNCiii in-in ActLoopNT-in 3.0177 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.84, 162.93 APE9-dihe-na 60.3, 141.79 APE8-dihe-in -61.19, 134.37 APE8-rot-in 300.22 APE67-dihe-in -64.11, -13.87 -46.21, -46.27 APE12-dist-in 13.3589 APE11-dist-in 10.8577 APE10-dist-in 6.8509 APE9-dist-in 3.1715 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 27 27 0 [[4, 284]] 1.0 AF-P20794-K1 CMGC_MAK_HUMAN CMGC 2.3e-84 289.1 1.0 301.0 301.0 142 143 144 146 148 33 50 54 122 124 123 125.0 182 169 164 163 162 161 160 159 158 80 Serine/threonine-protein kinase MAK
MAK AF-P20794-K3A P20794 1 292 623.0 No_ligand No_ligand Active DFGin 6.3411 15.0034 BLAminus -136.99, 179.15 59.57, 60.47 -73.07, 14.98 292.38, 83.86 -58.21, -31.54 in-in in 9.0141 Saltbr-in 2.7905 HRD-in -81.93, -45.54 70.35, -1.72 in-in-in SNCiii in-in ActLoopNT-in 2.9489 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.55, 166.23 APE9-dihe-na 62.07, 147.09 APE8-dihe-in -66.51, 134.5 APE8-rot-in 301.51 APE67-dihe-in -63.51, -15.12 -48.71, -50.59 APE12-dist-in 13.3603 APE11-dist-in 11.3683 APE10-dist-in 6.8952 APE9-dist-in 3.3388 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 27 27 0 [[4, 284]] 1.0 AF-P20794-K3 CMGC_MAK_HUMAN CMGC 2.3e-84 289.1 1.0 301.0 301.0 142 143 144 146 148 33 50 54 122 124 123 125.0 182 169 164 163 162 161 160 159 158 80 Serine/threonine-protein kinase MAK

CMGC_MAK (Serine/threonine-protein kinase MAK)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P20794-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAK MAK_HUMAN AF-P20794-K1A P20794 1 292 623.0 No_ligand No_ligand Active DFGin 6.4396 15.0129 BLAminus -134.23, 177.07 57.26, 69.59 -81.21, 18.58 288.24, 75.28 -58.77, -33.04 in-in in 8.9238 Saltbr-in 2.7971 HRD-in -78.15, -45.64 65.48, 7.28 in-in-in SNCiii in-in ActLoopNT-in 3.0177 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.84, 162.93 APE9-dihe-na 60.3, 141.79 APE8-dihe-in -61.19, 134.37 APE8-rot-in 300.22 APE67-dihe-in -64.11, -13.87 -46.21, -46.27 APE12-dist-in 13.3589 APE11-dist-in 10.8577 APE10-dist-in 6.8509 APE9-dist-in 3.1715 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 27 27 0 [[4, 284]] 1.0 AF-P20794-K1 Homo sapiens CMGC_MAK_HUMAN CMGC 2.3e-84 289.1 1.0 301.0 301.0 142 143 144 146 148 33 50 54 122 124 123 125.0 182 169 164 163 162 161 160 159 158 80 Serine/threonine-protein kinase MAK
MAK MAK_HUMAN AF-P20794-K3A P20794 1 292 623.0 No_ligand No_ligand Active DFGin 6.3411 15.0034 BLAminus -136.99, 179.15 59.57, 60.47 -73.07, 14.98 292.38, 83.86 -58.21, -31.54 in-in in 9.0141 Saltbr-in 2.7905 HRD-in -81.93, -45.54 70.35, -1.72 in-in-in SNCiii in-in ActLoopNT-in 2.9489 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.55, 166.23 APE9-dihe-na 62.07, 147.09 APE8-dihe-in -66.51, 134.5 APE8-rot-in 301.51 APE67-dihe-in -63.51, -15.12 -48.71, -50.59 APE12-dist-in 13.3603 APE11-dist-in 11.3683 APE10-dist-in 6.8952 APE9-dist-in 3.3388 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 27 27 0 [[4, 284]] 1.0 AF-P20794-K3 Homo sapiens CMGC_MAK_HUMAN CMGC 2.3e-84 289.1 1.0 301.0 301.0 142 143 144 146 148 33 50 54 122 124 123 125.0 182 169 164 163 162 161 160 159 158 80 Serine/threonine-protein kinase MAK

CMGC_MAK (Serine/threonine-protein kinase MAK)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name