TYR_INSRR (Insulin receptor-related protein)

Total number of chains: 2
Active chains: 2
Uniprot: INSRR_HUMAN
Kinase Domain Residues: 979 - 1248
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P14616-K1A

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Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
INSRR AF-P14616-K1A P14616 971 1256 1297.0 No_ligand No_ligand Active DFGin 6.5014 13.4517 BLAminus -133.12, -173.27 48.11, 84.14 -94.08, 13.01 301.53, 102.19 -58.68, -32.16 in-in in 8.1477 Saltbr-in 2.6923 HRD-in -71.81, -43.48 68.6, -17.95 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.36, 138.98 APE9-dihe-in -138.26, 136.83 APE8-dihe-in -78.36, 66.24 APE8-rot-na 35.25 APE67-dihe-in -75.45, -10.88 -44.8, -40.09 APE12-dist-na 14.8625 APE11-dist-na 10.8464 APE10-dist-na 9.9767 APE9-dist-in 6.896 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[979, 1248]] 1.0 AF-P14616-K1 TYR_INSRR_HUMAN TYR 2e-91 311.8 1.0 260.0 260.0 1132 1133 1134 1136 1138 1013 1030 1034 1112 1114 1113 1115.0 1174 1162 1157 1156 1155 1154 1153 1152 1151 1060 Insulin receptor-related protein
INSRR AF-P14616-K3A P14616 971 1256 1297.0 No_ligand No_ligand Active DFGin 6.0985 13.1377 BLAminus -136.85, -171.31 48.08, 79.39 -88.05, 13.52 307.38, 100.33 -57.79, -32.22 in-in in 8.1862 Saltbr-in 2.7366 HRD-in -76.52, -43.04 68.22, -9.61 in-in-in SNCiii in-in ActLoopNT-in 2.9554 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.06, 114.34 APE9-dihe-in -136.14, 149.1 APE8-dihe-in -79.54, 60.54 APE8-rot-na 36.18 APE67-dihe-in -75.82, -13.36 -51.69, -32.5 APE12-dist-na 16.1348 APE11-dist-na 11.9002 APE10-dist-na 10.8515 APE9-dist-in 7.06 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[979, 1248]] 1.0 AF-P14616-K3 TYR_INSRR_HUMAN TYR 2e-91 311.8 1.0 260.0 260.0 1132 1133 1134 1136 1138 1013 1030 1034 1112 1114 1113 1115.0 1174 1162 1157 1156 1155 1154 1153 1152 1151 1060 Insulin receptor-related protein

TYR_INSRR (Insulin receptor-related protein)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P14616-K1A

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
INSRR INSRR_HUMAN AF-P14616-K1A P14616 971 1256 1297.0 No_ligand No_ligand Active DFGin 6.5014 13.4517 BLAminus -133.12, -173.27 48.11, 84.14 -94.08, 13.01 301.53, 102.19 -58.68, -32.16 in-in in 8.1477 Saltbr-in 2.6923 HRD-in -71.81, -43.48 68.6, -17.95 in-in-in SNCiii in-in ActLoopNT-in 2.95 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.36, 138.98 APE9-dihe-in -138.26, 136.83 APE8-dihe-in -78.36, 66.24 APE8-rot-na 35.25 APE67-dihe-in -75.45, -10.88 -44.8, -40.09 APE12-dist-na 14.8625 APE11-dist-na 10.8464 APE10-dist-na 9.9767 APE9-dist-in 6.896 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[979, 1248]] 1.0 AF-P14616-K1 Homo sapiens TYR_INSRR_HUMAN TYR 2e-91 311.8 1.0 260.0 260.0 1132 1133 1134 1136 1138 1013 1030 1034 1112 1114 1113 1115.0 1174 1162 1157 1156 1155 1154 1153 1152 1151 1060 Insulin receptor-related protein
INSRR INSRR_HUMAN AF-P14616-K3A P14616 971 1256 1297.0 No_ligand No_ligand Active DFGin 6.0985 13.1377 BLAminus -136.85, -171.31 48.08, 79.39 -88.05, 13.52 307.38, 100.33 -57.79, -32.22 in-in in 8.1862 Saltbr-in 2.7366 HRD-in -76.52, -43.04 68.22, -9.61 in-in-in SNCiii in-in ActLoopNT-in 2.9554 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.06, 114.34 APE9-dihe-in -136.14, 149.1 APE8-dihe-in -79.54, 60.54 APE8-rot-na 36.18 APE67-dihe-in -75.82, -13.36 -51.69, -32.5 APE12-dist-na 16.1348 APE11-dist-na 11.9002 APE10-dist-na 10.8515 APE9-dist-in 7.06 None None None AF2 -1.0 1.0 1.0 A 286.0 286.0 0 30 30 0 [[979, 1248]] 1.0 AF-P14616-K3 Homo sapiens TYR_INSRR_HUMAN TYR 2e-91 311.8 1.0 260.0 260.0 1132 1133 1134 1136 1138 1013 1030 1034 1112 1114 1113 1115.0 1174 1162 1157 1156 1155 1154 1153 1152 1151 1060 Insulin receptor-related protein

TYR_INSRR (Insulin receptor-related protein)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name