KinCore

RGC_GUCY2C (Guanylyl cyclase C)

Total number of chains: 1

Active chains: 0

Uniprot: GUC2C_HUMAN

Kinase Domain Residues: 489 - 747

Spatial label	Dihedral label	Number of Chains	Percent	Representative
None	None	1	100.0%	8FX4D

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Gene	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
GUCY2C	8FX4D	P25092	550	755	1073.0	No_ligand	No_ligand	Pseudo	None	999.0	999.0	None	-103.03, -170.69	-90.03, -54.6	59.24, -64.74	158.72, 66.25	-58.61, -37.07	none-none	none	999.0	Saltbr-none	999.0	HRD-in	-94.68, -61.25	97.05, -18.95	none-none-out	SNCnno	none-out	ActLoopNT-none	999.0	ActLoopCT-out	nonTYR	APEdihe_aaiao	APEdist_iioo	APE10-dihe-na	-89.56, 18.63	APE9-dihe-na	-68.85, 85.4	APE8-dihe-in	-65.22, 138.25	APE8-rot-na	189.13	APE67-dihe-out	-65.39, -17.44	-155.76, 166.0	APE12-dist-in	12.9105	APE11-dist-in	10.1125	APE10-dist-out	15.6846	APE9-dist-out	10.5667	None	None	None	EM	3.9	999.0	999.0	D	741.0	203.0	64	19	16	3	[[489, 747]]	1.0	8fx4	RGC_GUCY2C_HUMAN	RGC	3.4e-106	361.1	2.0	265.0	264.0	631	632	633	635	637	516	532	536	611	613	612	614.0	662	650	645	644	643	642	641	640	639	562	Guanylyl cyclase C

RGC_GUCY2C (Guanylyl cyclase C)

Total number of chains: 1

Active chains: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative
None	None	1	100.0%	8FX4D

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Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
GUCY2C	GUC2C_HUMAN	8FX4D	P25092	550	755	1073.0	No_ligand	No_ligand	Pseudo	None	999.0	999.0	None	-103.03, -170.69	-90.03, -54.6	59.24, -64.74	158.72, 66.25	-58.61, -37.07	none-none	none	999.0	Saltbr-none	999.0	HRD-in	-94.68, -61.25	97.05, -18.95	none-none-out	SNCnno	none-out	ActLoopNT-none	999.0	ActLoopCT-out	nonTYR	APEdihe_aaiao	APEdist_iioo	APE10-dihe-na	-89.56, 18.63	APE9-dihe-na	-68.85, 85.4	APE8-dihe-in	-65.22, 138.25	APE8-rot-na	189.13	APE67-dihe-out	-65.39, -17.44	-155.76, 166.0	APE12-dist-in	12.9105	APE11-dist-in	10.1125	APE10-dist-out	15.6846	APE9-dist-out	10.5667	None	None	None	EM	3.9	999.0	999.0	D	741.0	203.0	64	19	16	3	[[489, 747]]	1.0	8fx4	Homo sapiens	RGC_GUCY2C_HUMAN	RGC	3.4e-106	361.1	2.0	265.0	264.0	631	632	633	635	637	516	532	536	611	613	612	614.0	662	650	645	644	643	642	641	640	639	562	Guanylyl cyclase C

RGC_GUCY2C (Guanylyl cyclase C)

Total number of chains: 0

Active chains: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative

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Hover over column headers for tooltip help.

Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name