CMGC_GSK3 (Glycogen synthase kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

CMGC_GSK3 (Glycogen synthase kinase 3)

Total number of chains: 4
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7S6UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
GSK3 A4HXQ3_LEIIN 7S6UA A4HXQ3 1 353 355.0 FB8:401 Type1 Inactive DFGin 6.761 14.0145 BLAminus -139.61, -164.97 65.25, 65.69 -95.51, 21.7 299.47, 94.31 -60.21, -32.44 in-in in 8.3294 Saltbr-in 2.8017 HRD-in -70.31, -44.47 65.55, 8.87 in-in-out SNCiio in-out ActLoopNT-in 2.9425 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -119.0, 166.74 APE9-dihe-na 84.7, 154.19 APE8-dihe-in -74.92, 140.06 APE8-rot-out 204.39 APE67-dihe-in -68.68, -21.33 -49.76, -38.05 APE12-dist-in 13.0724 APE11-dist-in 11.5969 APE10-dist-in 6.3641 APE9-dist-in 3.3114 None PTR186 PTR186 XRAY 1.74 0.175 0.2 A 356.0 351.0 2 27 27 0 [[20, 313]] 1.0 7s6u Leishmania infantum CMGC_GSK3_LEIIN CMGC 2.1e-63 220.5 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Glycogen synthase kinase 3
GSK3 A4HXQ3_LEIIN 7S6VA A4HXQ3 1 353 355.0 8II:401 Type1 Inactive DFGin 6.8571 14.1863 BLAminus -144.76, -177.73 75.59, 66.95 -92.98, 18.31 299.71, 93.39 -56.56, -31.86 in-in in 8.487 Saltbr-in 3.4844 HRD-in -66.49, -47.42 74.03, -4.68 in-in-out SNCiio in-out ActLoopNT-in 2.987 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.88, 164.04 APE9-dihe-na 78.2, 158.59 APE8-dihe-in -81.09, 139.95 APE8-rot-out 196.43 APE67-dihe-in -67.1, -15.84 -49.32, -44.52 APE12-dist-in 12.8465 APE11-dist-in 11.5187 APE10-dist-in 6.7323 APE9-dist-in 3.2137 None PTR186 PTR186 XRAY 1.66 0.185 0.215 A 356.0 345.0 8 27 27 0 [[20, 313]] 1.0 7s6v Leishmania infantum CMGC_GSK3_LEIIN CMGC 2.1e-63 220.5 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Glycogen synthase kinase 3
GSK3 Q4QE15_LEIMA 3E3PB Q4QE15 7 353 355.0 No_ligand No_ligand Active DFGin 7.3406 14.1712 BLAminus -126.72, -174.48 60.15, 68.06 -82.03, 31.27 291.4, 80.36 -62.77, -34.23 in-in in 7.9859 Saltbr-in 2.4788 HRD-in -77.42, -44.31 73.62, -4.38 in-in-in SNCiii in-in ActLoopNT-in 2.8799 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -61.41, -44.35 APE9-dihe-na -71.94, 129.38 APE8-dihe-in -56.5, 142.42 APE8-rot-in 311.94 APE67-dihe-in -63.53, -21.0 -56.12, -48.42 APE12-dist-in 11.7302 APE11-dist-in 10.4143 APE10-dist-in 4.8735 APE9-dist-in 2.9783 None None None XRAY 2.0 0.226 0.271 B 360.0 337.0 10 27 27 0 [[20, 313]] 1.0 3e3p Leishmania major CMGC_GSK3_LEIMA CMGC 9.3e-64 221.6 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Putative glycogen synthase kinase
GSK3 Q4QE15_LEIMA 3E3PA Q4QE15 7 353 355.0 No_ligand No_ligand Inactive DFGin 7.1666 13.8791 BLAminus -128.99, -178.11 60.98, 80.37 -93.78, 26.64 291.97, 73.1 -69.31, -7.19 in-out in 7.506 Saltbr-out 3.6447 HRD-in -65.43, -48.98 74.14, 2.57 out-in-in SNCoii in-in ActLoopNT-in 2.9718 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -64.96, -25.59 APE9-dihe-na -81.93, 131.56 APE8-dihe-in -56.92, 141.17 APE8-rot-in 301.1 APE67-dihe-in -60.54, -20.67 -58.78, -47.26 APE12-dist-in 11.8353 APE11-dist-in 10.5165 APE10-dist-in 4.8468 APE9-dist-in 3.0835 None None None XRAY 2.0 0.226 0.271 A 360.0 337.0 10 27 27 0 [[20, 313]] 1.0 3e3p Leishmania major CMGC_GSK3_LEIMA CMGC 9.3e-64 221.6 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Putative glycogen synthase kinase

CMGC_GSK3 (Glycogen synthase kinase 3)

Total number of chains: 4
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7S6UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
GSK3 A4HXQ3_LEIIN 7S6UA A4HXQ3 1 353 355.0 FB8:401 Type1 Inactive DFGin 6.761 14.0145 BLAminus -139.61, -164.97 65.25, 65.69 -95.51, 21.7 299.47, 94.31 -60.21, -32.44 in-in in 8.3294 Saltbr-in 2.8017 HRD-in -70.31, -44.47 65.55, 8.87 in-in-out SNCiio in-out ActLoopNT-in 2.9425 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -119.0, 166.74 APE9-dihe-na 84.7, 154.19 APE8-dihe-in -74.92, 140.06 APE8-rot-out 204.39 APE67-dihe-in -68.68, -21.33 -49.76, -38.05 APE12-dist-in 13.0724 APE11-dist-in 11.5969 APE10-dist-in 6.3641 APE9-dist-in 3.3114 None PTR186 PTR186 XRAY 1.74 0.175 0.2 A 356.0 351.0 2 27 27 0 [[20, 313]] 1.0 7s6u Leishmania infantum CMGC_GSK3_LEIIN CMGC 2.1e-63 220.5 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Glycogen synthase kinase 3
GSK3 A4HXQ3_LEIIN 7S6VA A4HXQ3 1 353 355.0 8II:401 Type1 Inactive DFGin 6.8571 14.1863 BLAminus -144.76, -177.73 75.59, 66.95 -92.98, 18.31 299.71, 93.39 -56.56, -31.86 in-in in 8.487 Saltbr-in 3.4844 HRD-in -66.49, -47.42 74.03, -4.68 in-in-out SNCiio in-out ActLoopNT-in 2.987 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.88, 164.04 APE9-dihe-na 78.2, 158.59 APE8-dihe-in -81.09, 139.95 APE8-rot-out 196.43 APE67-dihe-in -67.1, -15.84 -49.32, -44.52 APE12-dist-in 12.8465 APE11-dist-in 11.5187 APE10-dist-in 6.7323 APE9-dist-in 3.2137 None PTR186 PTR186 XRAY 1.66 0.185 0.215 A 356.0 345.0 8 27 27 0 [[20, 313]] 1.0 7s6v Leishmania infantum CMGC_GSK3_LEIIN CMGC 2.1e-63 220.5 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Glycogen synthase kinase 3
GSK3 Q4QE15_LEIMA 3E3PB Q4QE15 7 353 355.0 No_ligand No_ligand Active DFGin 7.3406 14.1712 BLAminus -126.72, -174.48 60.15, 68.06 -82.03, 31.27 291.4, 80.36 -62.77, -34.23 in-in in 7.9859 Saltbr-in 2.4788 HRD-in -77.42, -44.31 73.62, -4.38 in-in-in SNCiii in-in ActLoopNT-in 2.8799 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -61.41, -44.35 APE9-dihe-na -71.94, 129.38 APE8-dihe-in -56.5, 142.42 APE8-rot-in 311.94 APE67-dihe-in -63.53, -21.0 -56.12, -48.42 APE12-dist-in 11.7302 APE11-dist-in 10.4143 APE10-dist-in 4.8735 APE9-dist-in 2.9783 None None None XRAY 2.0 0.226 0.271 B 360.0 337.0 10 27 27 0 [[20, 313]] 1.0 3e3p Leishmania major CMGC_GSK3_LEIMA CMGC 9.3e-64 221.6 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Putative glycogen synthase kinase
GSK3 Q4QE15_LEIMA 3E3PA Q4QE15 7 353 355.0 No_ligand No_ligand Inactive DFGin 7.1666 13.8791 BLAminus -128.99, -178.11 60.98, 80.37 -93.78, 26.64 291.97, 73.1 -69.31, -7.19 in-out in 7.506 Saltbr-out 3.6447 HRD-in -65.43, -48.98 74.14, 2.57 out-in-in SNCoii in-in ActLoopNT-in 2.9718 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -64.96, -25.59 APE9-dihe-na -81.93, 131.56 APE8-dihe-in -56.92, 141.17 APE8-rot-in 301.1 APE67-dihe-in -60.54, -20.67 -58.78, -47.26 APE12-dist-in 11.8353 APE11-dist-in 10.5165 APE10-dist-in 4.8468 APE9-dist-in 3.0835 None None None XRAY 2.0 0.226 0.271 A 360.0 337.0 10 27 27 0 [[20, 313]] 1.0 3e3p Leishmania major CMGC_GSK3_LEIMA CMGC 9.3e-64 221.6 1.0 301.0 301.0 169 170 171 173 175 49 61 65 148 150 149 151.0 209 196 191 190 189 188 187 186 185 101 Putative glycogen synthase kinase