TYR_FYN (Tyrosine-protein kinase Fyn)

Total number of chains: 3
Active chains: 3
Uniprot: FYN_HUMAN
Kinase Domain Residues: 271 - 522
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P06241-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FYN AF-P06241-K1A P06241 263 530 537.0 No_ligand No_ligand Active DFGin 6.3537 14.0277 BLAminus -126.55, -167.91 45.27, 71.05 -84.21, 13.19 294.68, 92.8 -58.13, -32.62 in-in in 7.8851 Saltbr-in 2.6623 HRD-in -88.86, -44.97 65.41, 0.13 in-in-in SNCiii in-in ActLoopNT-in 2.8874 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.73, 133.47 APE9-dihe-in -122.55, 153.74 APE8-dihe-in -71.55, 86.34 APE8-rot-na 31.29 APE67-dihe-in -69.58, -20.71 -41.18, -38.77 APE12-dist-na 14.8575 APE11-dist-na 10.0631 APE10-dist-na 12.5194 APE9-dist-in 6.567 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[271, 522]] 1.0 AF-P06241-K1 TYR_FYN_HUMAN TYR 2.2e-94 321.5 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn
FYN AF-P06241-K3A P06241 263 530 537.0 No_ligand No_ligand Active DFGin 5.8288 13.974 BLAminus -139.06, 179.18 58.84, 64.33 -76.05, 11.69 292.9, 86.79 -59.0, -30.08 in-in in 7.9137 Saltbr-in 2.6472 HRD-in -88.09, -42.86 65.06, -6.28 in-in-in SNCiii in-in ActLoopNT-in 2.8904 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.57, 135.11 APE9-dihe-in -132.72, 154.72 APE8-dihe-in -73.76, 74.1 APE8-rot-na 37.44 APE67-dihe-in -66.92, -13.13 -41.86, -41.71 APE12-dist-na 13.4869 APE11-dist-na 8.8133 APE10-dist-na 9.8374 APE9-dist-in 5.7061 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[271, 522]] 1.0 AF-P06241-K3 TYR_FYN_HUMAN TYR 2.2e-94 321.5 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn
FYN 2DQ7X P06241 261 523 537.0 STU:60902 Type1 Active DFGin 6.9701 13.8533 BLAminus -137.79, 173.21 69.46, 82.83 -98.97, 30.24 286.34, 86.38 -56.5, -37.75 in-in in 7.7541 Saltbr-in 2.468 HRD-in -90.12, -49.46 72.41, 2.38 in-in-in SNCiii in-in ActLoopNT-in 2.8825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.8, 126.18 APE9-dihe-in -111.81, 159.77 APE8-dihe-in -55.65, 79.81 APE8-rot-na 29.61 APE67-dihe-in -72.56, -28.8 -30.08, -40.64 APE12-dist-na 13.298 APE11-dist-na 8.6792 APE10-dist-na 12.4565 APE9-dist-in 6.2157 None PTR420 PTR420 XRAY 2.8 0.255 0.281 X 283.0 263.0 0 29 29 0 [[271, 522]] 1.0 2dq7 TYR_FYN_HUMAN TYR 2.6e-94 321.3 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn

TYR_FYN (Tyrosine-protein kinase Fyn)

Total number of chains: 3
Active chains: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P06241-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FYN FYN_HUMAN AF-P06241-K1A P06241 263 530 537.0 No_ligand No_ligand Active DFGin 6.3537 14.0277 BLAminus -126.55, -167.91 45.27, 71.05 -84.21, 13.19 294.68, 92.8 -58.13, -32.62 in-in in 7.8851 Saltbr-in 2.6623 HRD-in -88.86, -44.97 65.41, 0.13 in-in-in SNCiii in-in ActLoopNT-in 2.8874 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.73, 133.47 APE9-dihe-in -122.55, 153.74 APE8-dihe-in -71.55, 86.34 APE8-rot-na 31.29 APE67-dihe-in -69.58, -20.71 -41.18, -38.77 APE12-dist-na 14.8575 APE11-dist-na 10.0631 APE10-dist-na 12.5194 APE9-dist-in 6.567 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[271, 522]] 1.0 AF-P06241-K1 Homo sapiens TYR_FYN_HUMAN TYR 2.2e-94 321.5 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn
FYN FYN_HUMAN AF-P06241-K3A P06241 263 530 537.0 No_ligand No_ligand Active DFGin 5.8288 13.974 BLAminus -139.06, 179.18 58.84, 64.33 -76.05, 11.69 292.9, 86.79 -59.0, -30.08 in-in in 7.9137 Saltbr-in 2.6472 HRD-in -88.09, -42.86 65.06, -6.28 in-in-in SNCiii in-in ActLoopNT-in 2.8904 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.57, 135.11 APE9-dihe-in -132.72, 154.72 APE8-dihe-in -73.76, 74.1 APE8-rot-na 37.44 APE67-dihe-in -66.92, -13.13 -41.86, -41.71 APE12-dist-na 13.4869 APE11-dist-na 8.8133 APE10-dist-na 9.8374 APE9-dist-in 5.7061 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[271, 522]] 1.0 AF-P06241-K3 Homo sapiens TYR_FYN_HUMAN TYR 2.2e-94 321.5 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn
FYN FYN_HUMAN 2DQ7X P06241 261 523 537.0 STU:60902 Type1 Active DFGin 6.9701 13.8533 BLAminus -137.79, 173.21 69.46, 82.83 -98.97, 30.24 286.34, 86.38 -56.5, -37.75 in-in in 7.7541 Saltbr-in 2.468 HRD-in -90.12, -49.46 72.41, 2.38 in-in-in SNCiii in-in ActLoopNT-in 2.8825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.8, 126.18 APE9-dihe-in -111.81, 159.77 APE8-dihe-in -55.65, 79.81 APE8-rot-na 29.61 APE67-dihe-in -72.56, -28.8 -30.08, -40.64 APE12-dist-na 13.298 APE11-dist-na 8.6792 APE10-dist-na 12.4565 APE9-dist-in 6.2157 None PTR420 PTR420 XRAY 2.8 0.255 0.281 X 283.0 263.0 0 29 29 0 [[271, 522]] 1.0 2dq7 Homo sapiens TYR_FYN_HUMAN TYR 2.6e-94 321.3 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 343 Tyrosine-protein kinase Fyn

TYR_FYN (Tyrosine-protein kinase Fyn)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name