CMGC_FUS3 (Mitogen-activated protein kinase FUS3)

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

CMGC_FUS3 (Mitogen-activated protein kinase FUS3)

Total number of chains: 9
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 100.0% 2B9IA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FUS3_YEAST 2B9HA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.283 13.764 BLAminus -136.62, -177.7 68.6, 65.84 -94.91, 10.48 297.74, 102.72 -75.81, -10.99 in-in in 8.564 Saltbr-in 2.732 HRD-in -74.04, -48.55 74.11, -6.87 in-in-out SNCiio in-out ActLoopNT-in 2.932 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.55, 132.5 APE9-dihe-na -63.29, 147.56 APE8-dihe-in -50.7, 127.74 APE8-rot-in 296.79 APE67-dihe-in -63.13, -20.59 -60.61, -24.81 APE12-dist-in 8.605 APE11-dist-out 6.693 APE10-dist-out 9.836 APE9-dist-in 4.75 T180V,Y182F None None XRAY 1.55 0.187 0.216 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9h Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9IA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.365 14.066 BLAminus -135.63, 178.36 68.62, 72.5 -98.81, 8.36 296.13, 97.35 -58.15, -32.2 in-in in 8.702 Saltbr-in 2.95 HRD-in -67.33, -47.39 70.79, -9.55 in-in-out SNCiio in-out ActLoopNT-in 2.954 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.27, 137.29 APE9-dihe-na -73.31, 133.1 APE8-dihe-in -36.03, 128.5 APE8-rot-in 289.53 APE67-dihe-in -68.8, -14.68 -68.0, -19.59 APE12-dist-in 8.905 APE11-dist-out 6.581 APE10-dist-out 9.961 APE9-dist-in 4.55 T180V,Y182F None None XRAY 2.5 0.202 0.279 A 353 338 15 0 0 15 [[13, 309]] 1.0 2b9i Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9JA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.547 13.868 BLAminus -134.9, -176.68 60.68, 67.3 -98.24, 14.73 302.06, 96.25 -69.67, -26.86 in-in in 8.701 Saltbr-in 2.96 HRD-in -72.32, -48.06 70.0, -6.29 in-in-out SNCiio in-out ActLoopNT-in 2.966 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -102.32, 139.79 APE9-dihe-na -71.76, 150.07 APE8-dihe-in -56.91, 118.63 APE8-rot-in 300.43 APE67-dihe-in -59.09, -25.02 -50.5, -31.25 APE12-dist-in 8.853 APE11-dist-out 6.593 APE10-dist-out 10.065 APE9-dist-in 4.766 T180V,Y182F None None XRAY 2.3 0.196 0.263 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9j Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9FA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.319 13.814 BLAminus -136.19, -174.38 64.52, 61.38 -89.09, 7.19 299.63, 104.82 -67.16, -21.09 in-in in 8.611 Saltbr-in 2.683 HRD-in -75.04, -47.21 75.53, -13.96 in-in-out SNCiio in-out ActLoopNT-in 3.045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -129.66, 156.16 APE9-dihe-na -66.55, 158.23 APE8-dihe-in -56.07, 140.2 APE8-rot-in 288.73 APE67-dihe-in -58.7, -27.3 -59.52, -33.17 APE12-dist-in 8.681 APE11-dist-out 5.798 APE10-dist-out 8.573 APE9-dist-in 4.092 None None None XRAY 1.8 0.213 0.259 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9f Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 5.2e-75 258.5 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F49A P16892 3 353 353.0 No_ligand No_ligand Inactive DFGin 6.779 16.709 BLAminus -144.19, -171.93 64.87, 64.42 -91.75, 26.27 287.39, 91.02 -61.26, -26.4 in-out in 9.524 Saltbr-out 5.292 HRD-in -73.91, -48.3 72.91, -0.8 out-in-out SNCoio in-out ActLoopNT-in 3.07 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -132.03, 150.18 APE9-dihe-na -64.05, -41.19 APE8-dihe-in -149.65, 154.08 APE8-rot-out 173.98 APE67-dihe-in -58.82, -22.87 -108.66, 12.14 APE12-dist-in 7.115 APE11-dist-in 9.468 APE10-dist-out 8.342 APE9-dist-out 9.853 T180V,Y182F None None XRAY 1.9 0.201 0.234 A 353 335 16 0 0 16 [[13, 309]] 1.0 2f49 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F49B P16892 1 353 353.0 No_ligand No_ligand Inactive DFGin 6.825 16.957 BLAminus -146.94, -173.47 68.01, 64.44 -94.22, 27.17 286.72, 90.27 -61.19, -31.27 in-out in 9.636 Saltbr-out 4.268 HRD-in -75.89, -48.13 69.31, 2.08 out-in-out SNCoio in-out ActLoopNT-in 3.018 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -123.65, 157.47 APE9-dihe-na -68.62, -49.07 APE8-dihe-in -151.54, 163.95 APE8-rot-out 88.97 APE67-dihe-in -61.05, -26.62 -108.12, 22.35 APE12-dist-in 7.902 APE11-dist-in 9.328 APE10-dist-out 8.57 APE9-dist-out 9.757 T180V,Y182F None None XRAY 1.9 0.201 0.234 B 353 337 16 0 0 16 [[13, 309]] 1.0 2f49 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2FA2A P16892 5 353 353.0 No_ligand No_ligand Inactive DFGin 6.598 16.77 BLAminus -151.09, -175.46 69.43, 70.3 -97.15, 34.59 294.29, 78.08 -65.02, -15.85 in-out in 9.717 Saltbr-out 5.614 HRD-in -60.79, -49.11 71.71, 5.38 out-in-out SNCoio in-out ActLoopNT-in 2.908 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -145.0, 155.42 APE9-dihe-na -74.32, -24.32 APE8-dihe-in -176.33, 155.06 APE8-rot-out 196.7 APE67-dihe-in -62.33, -20.32 -104.89, 24.76 APE12-dist-in 8.462 APE11-dist-in 9.576 APE10-dist-out 8.807 APE9-dist-out 9.898 T180V,Y182F None None XRAY 2.85 0.209 0.285 A 353 333 16 0 0 16 [[13, 309]] 1.0 2fa2 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2FA2B P16892 6 353 353.0 No_ligand No_ligand Inactive DFGin 6.689 16.84 BLAminus -141.78, -168.61 62.6, 69.27 -93.29, 25.68 289.17, 98.03 -61.65, -13.56 in-out in 9.414 Saltbr-out 4.045 HRD-in -73.83, -46.28 65.59, 9.53 out-in-out SNCoio in-out ActLoopNT-in 3.129 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -142.34, 155.34 APE9-dihe-na -71.88, -35.66 APE8-dihe-in -158.14, 165.35 APE8-rot-out 51.93 APE67-dihe-in -60.96, -17.63 -119.03, 21.6 APE12-dist-out 6.93 APE11-dist-in 9.457 APE10-dist-out 8.666 APE9-dist-out 10.169 T180V,Y182F None None XRAY 2.85 0.209 0.285 B 353 332 16 0 0 16 [[13, 309]] 1.0 2fa2 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F9GA P16892 1 353 353.0 ADP:500 ATPlike None DFGin 6.607 14.033 BLAminus -131.87, -173.96 62.19, 67.37 -94.01, 7.54 292.42, 102.61 -61.43, -28.32 in-in in 8.738 Saltbr-in 2.766 HRD-in -77.05, -50.83 75.67, -3.23 in-in-none SNCiin in-none ActLoopNT-in 2.955 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 121.43 APE8-rot-in 296.4 APE67-dihe-in -62.22, -26.66 -58.62, -16.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None PTR182 PTR182 XRAY 2.1 0.211 0.26 A 353 332 21 0 0 21 [[13, 309]] 1.0 2f9g Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 5.2e-75 258.5 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3

CMGC_FUS3 (Mitogen-activated protein kinase FUS3)

Total number of chains: 9
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 100.0% 2B9IA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FUS3_YEAST 2B9HA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.283 13.764 BLAminus -136.62, -177.7 68.6, 65.84 -94.91, 10.48 297.74, 102.72 -75.81, -10.99 in-in in 8.564 Saltbr-in 2.732 HRD-in -74.04, -48.55 74.11, -6.87 in-in-out SNCiio in-out ActLoopNT-in 2.932 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.55, 132.5 APE9-dihe-na -63.29, 147.56 APE8-dihe-in -50.7, 127.74 APE8-rot-in 296.79 APE67-dihe-in -63.13, -20.59 -60.61, -24.81 APE12-dist-in 8.605 APE11-dist-out 6.693 APE10-dist-out 9.836 APE9-dist-in 4.75 T180V,Y182F None None XRAY 1.55 0.187 0.216 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9h Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9IA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.365 14.066 BLAminus -135.63, 178.36 68.62, 72.5 -98.81, 8.36 296.13, 97.35 -58.15, -32.2 in-in in 8.702 Saltbr-in 2.95 HRD-in -67.33, -47.39 70.79, -9.55 in-in-out SNCiio in-out ActLoopNT-in 2.954 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.27, 137.29 APE9-dihe-na -73.31, 133.1 APE8-dihe-in -36.03, 128.5 APE8-rot-in 289.53 APE67-dihe-in -68.8, -14.68 -68.0, -19.59 APE12-dist-in 8.905 APE11-dist-out 6.581 APE10-dist-out 9.961 APE9-dist-in 4.55 T180V,Y182F None None XRAY 2.5 0.202 0.279 A 353 338 15 0 0 15 [[13, 309]] 1.0 2b9i Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9JA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.547 13.868 BLAminus -134.9, -176.68 60.68, 67.3 -98.24, 14.73 302.06, 96.25 -69.67, -26.86 in-in in 8.701 Saltbr-in 2.96 HRD-in -72.32, -48.06 70.0, -6.29 in-in-out SNCiio in-out ActLoopNT-in 2.966 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -102.32, 139.79 APE9-dihe-na -71.76, 150.07 APE8-dihe-in -56.91, 118.63 APE8-rot-in 300.43 APE67-dihe-in -59.09, -25.02 -50.5, -31.25 APE12-dist-in 8.853 APE11-dist-out 6.593 APE10-dist-out 10.065 APE9-dist-in 4.766 T180V,Y182F None None XRAY 2.3 0.196 0.263 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9j Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2B9FA P16892 1 353 353.0 ADP:500 ATPlike Inactive DFGin 6.319 13.814 BLAminus -136.19, -174.38 64.52, 61.38 -89.09, 7.19 299.63, 104.82 -67.16, -21.09 in-in in 8.611 Saltbr-in 2.683 HRD-in -75.04, -47.21 75.53, -13.96 in-in-out SNCiio in-out ActLoopNT-in 3.045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -129.66, 156.16 APE9-dihe-na -66.55, 158.23 APE8-dihe-in -56.07, 140.2 APE8-rot-in 288.73 APE67-dihe-in -58.7, -27.3 -59.52, -33.17 APE12-dist-in 8.681 APE11-dist-out 5.798 APE10-dist-out 8.573 APE9-dist-in 4.092 None None None XRAY 1.8 0.213 0.259 A 353 337 16 0 0 16 [[13, 309]] 1.0 2b9f Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 5.2e-75 258.5 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F49A P16892 3 353 353.0 No_ligand No_ligand Inactive DFGin 6.779 16.709 BLAminus -144.19, -171.93 64.87, 64.42 -91.75, 26.27 287.39, 91.02 -61.26, -26.4 in-out in 9.524 Saltbr-out 5.292 HRD-in -73.91, -48.3 72.91, -0.8 out-in-out SNCoio in-out ActLoopNT-in 3.07 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -132.03, 150.18 APE9-dihe-na -64.05, -41.19 APE8-dihe-in -149.65, 154.08 APE8-rot-out 173.98 APE67-dihe-in -58.82, -22.87 -108.66, 12.14 APE12-dist-in 7.115 APE11-dist-in 9.468 APE10-dist-out 8.342 APE9-dist-out 9.853 T180V,Y182F None None XRAY 1.9 0.201 0.234 A 353 335 16 0 0 16 [[13, 309]] 1.0 2f49 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F49B P16892 1 353 353.0 No_ligand No_ligand Inactive DFGin 6.825 16.957 BLAminus -146.94, -173.47 68.01, 64.44 -94.22, 27.17 286.72, 90.27 -61.19, -31.27 in-out in 9.636 Saltbr-out 4.268 HRD-in -75.89, -48.13 69.31, 2.08 out-in-out SNCoio in-out ActLoopNT-in 3.018 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -123.65, 157.47 APE9-dihe-na -68.62, -49.07 APE8-dihe-in -151.54, 163.95 APE8-rot-out 88.97 APE67-dihe-in -61.05, -26.62 -108.12, 22.35 APE12-dist-in 7.902 APE11-dist-in 9.328 APE10-dist-out 8.57 APE9-dist-out 9.757 T180V,Y182F None None XRAY 1.9 0.201 0.234 B 353 337 16 0 0 16 [[13, 309]] 1.0 2f49 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2FA2A P16892 5 353 353.0 No_ligand No_ligand Inactive DFGin 6.598 16.77 BLAminus -151.09, -175.46 69.43, 70.3 -97.15, 34.59 294.29, 78.08 -65.02, -15.85 in-out in 9.717 Saltbr-out 5.614 HRD-in -60.79, -49.11 71.71, 5.38 out-in-out SNCoio in-out ActLoopNT-in 2.908 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -145.0, 155.42 APE9-dihe-na -74.32, -24.32 APE8-dihe-in -176.33, 155.06 APE8-rot-out 196.7 APE67-dihe-in -62.33, -20.32 -104.89, 24.76 APE12-dist-in 8.462 APE11-dist-in 9.576 APE10-dist-out 8.807 APE9-dist-out 9.898 T180V,Y182F None None XRAY 2.85 0.209 0.285 A 353 333 16 0 0 16 [[13, 309]] 1.0 2fa2 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2FA2B P16892 6 353 353.0 No_ligand No_ligand Inactive DFGin 6.689 16.84 BLAminus -141.78, -168.61 62.6, 69.27 -93.29, 25.68 289.17, 98.03 -61.65, -13.56 in-out in 9.414 Saltbr-out 4.045 HRD-in -73.83, -46.28 65.59, 9.53 out-in-out SNCoio in-out ActLoopNT-in 3.129 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -142.34, 155.34 APE9-dihe-na -71.88, -35.66 APE8-dihe-in -158.14, 165.35 APE8-rot-out 51.93 APE67-dihe-in -60.96, -17.63 -119.03, 21.6 APE12-dist-out 6.93 APE11-dist-in 9.457 APE10-dist-out 8.666 APE9-dist-out 10.169 T180V,Y182F None None XRAY 2.85 0.209 0.285 B 353 332 16 0 0 16 [[13, 309]] 1.0 2fa2 Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 2.2e-73 253.2 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3
FUS3_YEAST 2F9GA P16892 1 353 353.0 ADP:500 ATPlike None DFGin 6.607 14.033 BLAminus -131.87, -173.96 62.19, 67.37 -94.01, 7.54 292.42, 102.61 -61.43, -28.32 in-in in 8.738 Saltbr-in 2.766 HRD-in -77.05, -50.83 75.67, -3.23 in-in-none SNCiin in-none ActLoopNT-in 2.955 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 121.43 APE8-rot-in 296.4 APE67-dihe-in -62.22, -26.66 -58.62, -16.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None PTR182 PTR182 XRAY 2.1 0.211 0.26 A 353 332 21 0 0 21 [[13, 309]] 1.0 2f9g Saccharomyces cerevisiae CMGC_FUS3_YEAST CMGC 5.2e-75 258.5 3 301 299 154 155 156 158 160 42 59 63 134 136 135 137 205 192 187 186 185 184 183 182 181 94 Mitogen-activated protein kinase FUS3