TYR_FRK (Tyrosine-protein kinase FRK)

Total number of chains: 2
Active chains: 2
Uniprot: FRK_HUMAN
Kinase Domain Residues: 234 - 489
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P42685-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FRK AF-P42685-K1A P42685 226 497 505.0 No_ligand No_ligand Active DFGin 6.4781 14.0386 BLAminus -124.66, -159.52 36.16, 66.56 -79.85, 13.55 298.57, 99.27 -58.81, -35.57 in-in in 7.9523 Saltbr-in 2.643 HRD-in -84.52, -45.99 65.55, 3.84 in-in-in SNCiii in-in ActLoopNT-in 2.8692 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.91, 113.29 APE9-dihe-in -100.03, 144.91 APE8-dihe-in -72.58, 79.48 APE8-rot-na 32.04 APE67-dihe-in -70.67, -22.66 -42.44, -35.55 APE12-dist-na 14.9697 APE11-dist-na 9.1234 APE10-dist-na 12.6385 APE9-dist-in 7.1087 None None None AF2 -1.0 1.0 1.0 A 272.0 272.0 0 32 32 0 [[234, 489]] 1.0 AF-P42685-K1 TYR_FRK_HUMAN TYR 5.5e-99 336.6 1.0 260.0 260.0 371 372 373 375 377 262 277 281 351 353 352 354.0 415 403 398 397 396 395 394 393 392 307 Tyrosine-protein kinase FRK
FRK AF-P42685-K3A P42685 226 497 505.0 No_ligand No_ligand Active DFGin 6.0336 14.2249 BLAminus -140.56, -177.27 59.53, 63.27 -78.47, 12.45 300.41, 103.82 -60.2, -33.3 in-in in 8.3799 Saltbr-in 2.6722 HRD-in -80.86, -45.26 70.01, -11.79 in-in-in SNCiii in-in ActLoopNT-in 2.8984 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.96, 113.9 APE9-dihe-in -86.49, 146.93 APE8-dihe-in -77.87, 76.17 APE8-rot-na 30.89 APE67-dihe-in -72.42, -13.95 -41.42, -38.14 APE12-dist-na 12.3019 APE11-dist-na 7.6363 APE10-dist-na 11.1331 APE9-dist-in 6.5225 None None None AF2 -1.0 1.0 1.0 A 272.0 272.0 0 32 32 0 [[234, 489]] 1.0 AF-P42685-K3 TYR_FRK_HUMAN TYR 5.5e-99 336.6 1.0 260.0 260.0 371 372 373 375 377 262 277 281 351 353 352 354.0 415 403 398 397 396 395 394 393 392 307 Tyrosine-protein kinase FRK

TYR_FRK (Tyrosine-protein kinase FRK)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P42685-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FRK FRK_HUMAN AF-P42685-K1A P42685 226 497 505.0 No_ligand No_ligand Active DFGin 6.4781 14.0386 BLAminus -124.66, -159.52 36.16, 66.56 -79.85, 13.55 298.57, 99.27 -58.81, -35.57 in-in in 7.9523 Saltbr-in 2.643 HRD-in -84.52, -45.99 65.55, 3.84 in-in-in SNCiii in-in ActLoopNT-in 2.8692 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.91, 113.29 APE9-dihe-in -100.03, 144.91 APE8-dihe-in -72.58, 79.48 APE8-rot-na 32.04 APE67-dihe-in -70.67, -22.66 -42.44, -35.55 APE12-dist-na 14.9697 APE11-dist-na 9.1234 APE10-dist-na 12.6385 APE9-dist-in 7.1087 None None None AF2 -1.0 1.0 1.0 A 272.0 272.0 0 32 32 0 [[234, 489]] 1.0 AF-P42685-K1 Homo sapiens TYR_FRK_HUMAN TYR 5.5e-99 336.6 1.0 260.0 260.0 371 372 373 375 377 262 277 281 351 353 352 354.0 415 403 398 397 396 395 394 393 392 307 Tyrosine-protein kinase FRK
FRK FRK_HUMAN AF-P42685-K3A P42685 226 497 505.0 No_ligand No_ligand Active DFGin 6.0336 14.2249 BLAminus -140.56, -177.27 59.53, 63.27 -78.47, 12.45 300.41, 103.82 -60.2, -33.3 in-in in 8.3799 Saltbr-in 2.6722 HRD-in -80.86, -45.26 70.01, -11.79 in-in-in SNCiii in-in ActLoopNT-in 2.8984 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.96, 113.9 APE9-dihe-in -86.49, 146.93 APE8-dihe-in -77.87, 76.17 APE8-rot-na 30.89 APE67-dihe-in -72.42, -13.95 -41.42, -38.14 APE12-dist-na 12.3019 APE11-dist-na 7.6363 APE10-dist-na 11.1331 APE9-dist-in 6.5225 None None None AF2 -1.0 1.0 1.0 A 272.0 272.0 0 32 32 0 [[234, 489]] 1.0 AF-P42685-K3 Homo sapiens TYR_FRK_HUMAN TYR 5.5e-99 336.6 1.0 260.0 260.0 371 372 373 375 377 262 277 281 351 353 352 354.0 415 403 398 397 396 395 394 393 392 307 Tyrosine-protein kinase FRK

TYR_FRK (Tyrosine-protein kinase FRK)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name