TYR_FLT4 (Vascular endothelial growth factor receptor 3)

Total number of chains: 2
Active chains: 2
Uniprot: VGFR3_HUMAN
Kinase Domain Residues: 845 - 1171
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P35916-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FLT4 AF-P35916-K1A P35916 837 1179 1363.0 No_ligand No_ligand Active DFGin 6.7131 13.8178 BLAminus -136.34, -179.38 65.22, 58.87 -79.49, 13.28 290.61, 84.42 -59.14, -27.7 in-in in 7.2629 Saltbr-in 2.6467 HRD-in -81.51, -43.46 66.21, -14.74 in-in-in SNCiii in-in ActLoopNT-in 2.9647 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.98, 112.01 APE9-dihe-in -127.37, 151.85 APE8-dihe-in -77.73, 86.65 APE8-rot-na 35.34 APE67-dihe-in -65.15, -23.81 -51.86, -33.13 APE12-dist-na 14.3222 APE11-dist-na 8.1049 APE10-dist-na 10.5308 APE9-dist-in 6.341 None None None AF2 -1.0 1.0 1.0 A 343.0 343.0 0 30 30 0 [[845, 1171]] 1.0 AF-P35916-K1 TYR_FLT4_HUMAN TYR 3.8e-99 337.2 1.0 259.0 259.0 1054 1055 1056 1058 1060 879 896 900 1034 1036 1035 1037.0 1096 1084 1079 1078 1077 1076 1075 1074 1073 928 Vascular endothelial growth factor receptor 3
FLT4 AF-P35916-K3A P35916 837 1179 1363.0 No_ligand No_ligand Active DFGin 6.3959 13.5236 BLAminus -138.12, -176.85 59.46, 64.48 -76.84, 16.03 288.78, 86.39 -61.72, -28.52 in-in in 7.7582 Saltbr-in 2.7042 HRD-in -83.53, -43.69 63.1, -3.86 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.45, 127.37 APE9-dihe-in -111.81, 124.32 APE8-dihe-in -79.95, 61.54 APE8-rot-na 35.53 APE67-dihe-in -64.42, -22.76 -48.92, -36.28 APE12-dist-na 13.0425 APE11-dist-na 7.3778 APE10-dist-na 8.5237 APE9-dist-in 6.8801 None None None AF2 -1.0 1.0 1.0 A 343.0 343.0 0 30 30 0 [[845, 1171]] 1.0 AF-P35916-K3 TYR_FLT4_HUMAN TYR 3.8e-99 337.2 1.0 259.0 259.0 1054 1055 1056 1058 1060 879 896 900 1034 1036 1035 1037.0 1096 1084 1079 1078 1077 1076 1075 1074 1073 928 Vascular endothelial growth factor receptor 3

TYR_FLT4 (Vascular endothelial growth factor receptor 3)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P35916-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FLT4 VGFR3_HUMAN AF-P35916-K1A P35916 837 1179 1363.0 No_ligand No_ligand Active DFGin 6.7131 13.8178 BLAminus -136.34, -179.38 65.22, 58.87 -79.49, 13.28 290.61, 84.42 -59.14, -27.7 in-in in 7.2629 Saltbr-in 2.6467 HRD-in -81.51, -43.46 66.21, -14.74 in-in-in SNCiii in-in ActLoopNT-in 2.9647 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.98, 112.01 APE9-dihe-in -127.37, 151.85 APE8-dihe-in -77.73, 86.65 APE8-rot-na 35.34 APE67-dihe-in -65.15, -23.81 -51.86, -33.13 APE12-dist-na 14.3222 APE11-dist-na 8.1049 APE10-dist-na 10.5308 APE9-dist-in 6.341 None None None AF2 -1.0 1.0 1.0 A 343.0 343.0 0 30 30 0 [[845, 1171]] 1.0 AF-P35916-K1 Homo sapiens TYR_FLT4_HUMAN TYR 3.8e-99 337.2 1.0 259.0 259.0 1054 1055 1056 1058 1060 879 896 900 1034 1036 1035 1037.0 1096 1084 1079 1078 1077 1076 1075 1074 1073 928 Vascular endothelial growth factor receptor 3
FLT4 VGFR3_HUMAN AF-P35916-K3A P35916 837 1179 1363.0 No_ligand No_ligand Active DFGin 6.3959 13.5236 BLAminus -138.12, -176.85 59.46, 64.48 -76.84, 16.03 288.78, 86.39 -61.72, -28.52 in-in in 7.7582 Saltbr-in 2.7042 HRD-in -83.53, -43.69 63.1, -3.86 in-in-in SNCiii in-in ActLoopNT-in 2.919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.45, 127.37 APE9-dihe-in -111.81, 124.32 APE8-dihe-in -79.95, 61.54 APE8-rot-na 35.53 APE67-dihe-in -64.42, -22.76 -48.92, -36.28 APE12-dist-na 13.0425 APE11-dist-na 7.3778 APE10-dist-na 8.5237 APE9-dist-in 6.8801 None None None AF2 -1.0 1.0 1.0 A 343.0 343.0 0 30 30 0 [[845, 1171]] 1.0 AF-P35916-K3 Homo sapiens TYR_FLT4_HUMAN TYR 3.8e-99 337.2 1.0 259.0 259.0 1054 1055 1056 1058 1060 879 896 900 1034 1036 1035 1037.0 1096 1084 1079 1078 1077 1076 1075 1074 1073 928 Vascular endothelial growth factor receptor 3

TYR_FLT4 (Vascular endothelial growth factor receptor 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name