TYR_EPHA6 (Ephrin type-A receptor 6)

Total number of chains: 2
Active chains: 2
Uniprot: EPHA6_HUMAN
Kinase Domain Residues: 631 - 932
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9UF33-K1A

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Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EPHA6 AF-Q9UF33-K1A Q9UF33 623 940 1036.0 No_ligand No_ligand Active DFGin 6.0106 14.2686 BLAminus -138.34, 177.11 64.65, 64.92 -83.88, 13.14 296.24, 94.85 -61.05, -34.51 in-in in 8.0792 Saltbr-in 2.7099 HRD-in -77.37, -46.9 70.01, -10.13 in-in-in SNCiii in-in ActLoopNT-in 2.9047 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.85, 134.93 APE9-dihe-in -106.92, 128.95 APE8-dihe-in -75.48, 82.39 APE8-rot-na 32.93 APE67-dihe-in -65.1, -16.98 -41.98, -51.3 APE12-dist-na 10.9174 APE11-dist-na 8.7881 APE10-dist-na 10.4022 APE9-dist-in 6.3946 None None None AF2 -1.0 1.0 1.0 A 318.0 318.0 0 31 31 0 [[631, 932]] 1.0 AF-Q9UF33-K1 TYR_EPHA6_HUMAN TYR 9.7e-110 371.9 1.0 261.0 261.0 815 816 817 819 821 663 680 684 795 797 796 798.0 858 846 841 840 839 838 837 836 835 752 Ephrin type-A receptor 6
EPHA6 AF-Q9UF33-K3A Q9UF33 623 940 1036.0 No_ligand No_ligand Active DFGin 6.1882 13.6014 BLAminus -143.29, 178.04 62.4, 65.37 -81.45, 12.2 301.8, 101.15 -59.04, -33.64 in-in in 8.0885 Saltbr-in 2.9106 HRD-in -77.13, -48.75 70.87, -9.47 in-in-in SNCiii in-in ActLoopNT-in 2.9312 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.31, 135.9 APE9-dihe-in -110.57, 132.82 APE8-dihe-in -74.83, 82.37 APE8-rot-na 35.01 APE67-dihe-in -63.64, -18.86 -43.38, -49.21 APE12-dist-na 11.4139 APE11-dist-na 9.1947 APE10-dist-na 10.7938 APE9-dist-in 6.4953 None None None AF2 -1.0 1.0 1.0 A 318.0 318.0 0 31 31 0 [[631, 932]] 1.0 AF-Q9UF33-K3 TYR_EPHA6_HUMAN TYR 9.7e-110 371.9 1.0 261.0 261.0 815 816 817 819 821 663 680 684 795 797 796 798.0 858 846 841 840 839 838 837 836 835 752 Ephrin type-A receptor 6

TYR_EPHA6 (Ephrin type-A receptor 6)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9UF33-K1A

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EPHA6 EPHA6_HUMAN AF-Q9UF33-K1A Q9UF33 623 940 1036.0 No_ligand No_ligand Active DFGin 6.0106 14.2686 BLAminus -138.34, 177.11 64.65, 64.92 -83.88, 13.14 296.24, 94.85 -61.05, -34.51 in-in in 8.0792 Saltbr-in 2.7099 HRD-in -77.37, -46.9 70.01, -10.13 in-in-in SNCiii in-in ActLoopNT-in 2.9047 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.85, 134.93 APE9-dihe-in -106.92, 128.95 APE8-dihe-in -75.48, 82.39 APE8-rot-na 32.93 APE67-dihe-in -65.1, -16.98 -41.98, -51.3 APE12-dist-na 10.9174 APE11-dist-na 8.7881 APE10-dist-na 10.4022 APE9-dist-in 6.3946 None None None AF2 -1.0 1.0 1.0 A 318.0 318.0 0 31 31 0 [[631, 932]] 1.0 AF-Q9UF33-K1 Homo sapiens TYR_EPHA6_HUMAN TYR 9.7e-110 371.9 1.0 261.0 261.0 815 816 817 819 821 663 680 684 795 797 796 798.0 858 846 841 840 839 838 837 836 835 752 Ephrin type-A receptor 6
EPHA6 EPHA6_HUMAN AF-Q9UF33-K3A Q9UF33 623 940 1036.0 No_ligand No_ligand Active DFGin 6.1882 13.6014 BLAminus -143.29, 178.04 62.4, 65.37 -81.45, 12.2 301.8, 101.15 -59.04, -33.64 in-in in 8.0885 Saltbr-in 2.9106 HRD-in -77.13, -48.75 70.87, -9.47 in-in-in SNCiii in-in ActLoopNT-in 2.9312 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.31, 135.9 APE9-dihe-in -110.57, 132.82 APE8-dihe-in -74.83, 82.37 APE8-rot-na 35.01 APE67-dihe-in -63.64, -18.86 -43.38, -49.21 APE12-dist-na 11.4139 APE11-dist-na 9.1947 APE10-dist-na 10.7938 APE9-dist-in 6.4953 None None None AF2 -1.0 1.0 1.0 A 318.0 318.0 0 31 31 0 [[631, 932]] 1.0 AF-Q9UF33-K3 Homo sapiens TYR_EPHA6_HUMAN TYR 9.7e-110 371.9 1.0 261.0 261.0 815 816 817 819 821 663 680 684 795 797 796 798.0 858 846 841 840 839 838 837 836 835 752 Ephrin type-A receptor 6

TYR_EPHA6 (Ephrin type-A receptor 6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name