TYR_EPHA5 (Ephrin type-A receptor 5)

Total number of chains: 3
Active chains: 2
Uniprot: EPHA5_HUMAN
Kinase Domain Residues: 675 - 934
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P54756-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EPHA5 AF-P54756-K1A P54756 667 942 1037.0 No_ligand No_ligand Active DFGin 5.8654 14.0822 BLAminus -139.46, 177.54 60.83, 70.04 -85.91, 14.31 302.6, 97.46 -58.94, -35.49 in-in in 8.1487 Saltbr-in 2.686 HRD-in -76.28, -45.84 68.81, -12.11 in-in-in SNCiii in-in ActLoopNT-in 2.8898 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.59, 134.7 APE9-dihe-in -116.66, 124.09 APE8-dihe-in -77.25, 81.47 APE8-rot-na 34.57 APE67-dihe-in -65.69, -15.3 -40.43, -55.09 APE12-dist-na 11.0593 APE11-dist-na 8.8493 APE10-dist-na 9.3691 APE9-dist-in 6.1318 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 31 31 0 [[675, 934]] 1.0 AF-P54756-K1 TYR_EPHA5_HUMAN TYR 7.7e-110 372.2 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5
EPHA5 AF-P54756-K3A P54756 667 942 1037.0 No_ligand No_ligand Active DFGin 5.9915 14.3582 BLAminus -143.15, -179.36 62.92, 63.72 -78.17, 9.48 293.68, 97.63 -59.57, -30.72 in-in in 8.0575 Saltbr-in 2.6855 HRD-in -79.29, -47.05 71.54, -10.04 in-in-in SNCiii in-in ActLoopNT-in 2.9231 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.15, 144.95 APE9-dihe-in -123.44, 128.93 APE8-dihe-in -77.89, 72.38 APE8-rot-na 35.13 APE67-dihe-in -66.69, -16.98 -36.69, -46.58 APE12-dist-na 11.448 APE11-dist-na 9.0678 APE10-dist-na 9.713 APE9-dist-in 6.2837 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 31 31 0 [[675, 934]] 1.0 AF-P54756-K3 TYR_EPHA5_HUMAN TYR 7.7e-110 372.2 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5
EPHA5 2R2PA P54756 662 939 1037.0 No_ligand No_ligand Inactive DFGin 5.9293 14.4485 BLAminus -137.18, -176.54 51.54, 82.79 -103.68, 29.05 308.02, 91.86 -58.78, -41.83 in-in in 8.3397 Saltbr-in 2.5976 HRD-in -76.26, -51.45 82.01, -15.97 in-in-out SNCiio in-out ActLoopNT-in 2.9487 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.92, 48.78 APE9-dihe-in -65.18, 120.88 APE8-dihe-in -84.07, 98.8 APE8-rot-na 26.64 APE67-dihe-in -74.82, -9.7 -61.15, -47.95 APE12-dist-na 999.0 APE11-dist-na 9.6687 APE10-dist-na 7.5751 APE9-dist-in 6.2565 None None None XRAY 2.4 0.203 0.283 A 295.0 276.0 2 31 29 2 [[675, 934]] 1.0 2r2p TYR_EPHA5_HUMAN TYR 9.9e-110 371.8 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5

TYR_EPHA5 (Ephrin type-A receptor 5)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-P54756-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EPHA5 EPHA5_HUMAN AF-P54756-K1A P54756 667 942 1037.0 No_ligand No_ligand Active DFGin 5.8654 14.0822 BLAminus -139.46, 177.54 60.83, 70.04 -85.91, 14.31 302.6, 97.46 -58.94, -35.49 in-in in 8.1487 Saltbr-in 2.686 HRD-in -76.28, -45.84 68.81, -12.11 in-in-in SNCiii in-in ActLoopNT-in 2.8898 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.59, 134.7 APE9-dihe-in -116.66, 124.09 APE8-dihe-in -77.25, 81.47 APE8-rot-na 34.57 APE67-dihe-in -65.69, -15.3 -40.43, -55.09 APE12-dist-na 11.0593 APE11-dist-na 8.8493 APE10-dist-na 9.3691 APE9-dist-in 6.1318 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 31 31 0 [[675, 934]] 1.0 AF-P54756-K1 Homo sapiens TYR_EPHA5_HUMAN TYR 7.7e-110 372.2 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5
EPHA5 EPHA5_HUMAN AF-P54756-K3A P54756 667 942 1037.0 No_ligand No_ligand Active DFGin 5.9915 14.3582 BLAminus -143.15, -179.36 62.92, 63.72 -78.17, 9.48 293.68, 97.63 -59.57, -30.72 in-in in 8.0575 Saltbr-in 2.6855 HRD-in -79.29, -47.05 71.54, -10.04 in-in-in SNCiii in-in ActLoopNT-in 2.9231 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.15, 144.95 APE9-dihe-in -123.44, 128.93 APE8-dihe-in -77.89, 72.38 APE8-rot-na 35.13 APE67-dihe-in -66.69, -16.98 -36.69, -46.58 APE12-dist-na 11.448 APE11-dist-na 9.0678 APE10-dist-na 9.713 APE9-dist-in 6.2837 None None None AF2 -1.0 1.0 1.0 A 276.0 276.0 0 31 31 0 [[675, 934]] 1.0 AF-P54756-K3 Homo sapiens TYR_EPHA5_HUMAN TYR 7.7e-110 372.2 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5
EPHA5 EPHA5_HUMAN 2R2PA P54756 662 939 1037.0 No_ligand No_ligand Inactive DFGin 5.9293 14.4485 BLAminus -137.18, -176.54 51.54, 82.79 -103.68, 29.05 308.02, 91.86 -58.78, -41.83 in-in in 8.3397 Saltbr-in 2.5976 HRD-in -76.26, -51.45 82.01, -15.97 in-in-out SNCiio in-out ActLoopNT-in 2.9487 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.92, 48.78 APE9-dihe-in -65.18, 120.88 APE8-dihe-in -84.07, 98.8 APE8-rot-na 26.64 APE67-dihe-in -74.82, -9.7 -61.15, -47.95 APE12-dist-na 999.0 APE11-dist-na 9.6687 APE10-dist-na 7.5751 APE9-dist-in 6.2565 None None None XRAY 2.4 0.203 0.283 A 295.0 276.0 2 31 29 2 [[675, 934]] 1.0 2r2p Homo sapiens TYR_EPHA5_HUMAN TYR 9.9e-110 371.8 1.0 261.0 261.0 817 818 819 821 823 707 724 728 797 799 798 800.0 860 848 843 842 841 840 839 838 837 754 Ephrin type-A receptor 5

TYR_EPHA5 (Ephrin type-A receptor 5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name