CAMK_DAPK3 (Death-associated protein kinase 3)

Total number of chains: 16
Active chains: 8
Family: CAMK
Uniprot: DAPK3_HUMAN
Kinase Domain Residues: 13 - 275
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 16 100.0% AF-O43293-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-O43293-K1A 5 283 454.0 No_ligand No_ligand Active DFGin 6.748 14.044 BLAminus -123.35, 175.18 57.14, 85.1 -91.34, 18.19 285.15, 81.66 -60.32, -31.25 in-in in 9.234 Saltbr-in 2.745 HRD-in -73.32, -40.76 62.86, -13.13 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.45, -179.33 APE9-dihe-na 83.48, 171.43 APE8-dihe-in -83.74, 124.14 APE8-rot-in 298.87 APE67-dihe-in -61.76, -27.25 -48.42, -36.53 APE12-dist-in 8.761 APE11-dist-in 11.759 APE10-dist-in 6.301 APE9-dist-in 5.093 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[13, 275]] 1.0 AF-O43293-K1 CAMK_DAPK3_HUMAN CAMK 8.9e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
AF-O43293-K3A 5 283 454.0 No_ligand No_ligand Active DFGin 6.714 14.117 BLAminus -125.53, -178.47 52.36, 75.24 -81.75, 15.99 283.01, 81.08 -55.71, -32.68 in-in in 9.322 Saltbr-in 2.723 HRD-in -78.84, -39.96 62.42, -3.08 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.11, -174.39 APE9-dihe-na 82.83, 170.05 APE8-dihe-in -79.78, 124.91 APE8-rot-in 299.59 APE67-dihe-in -71.44, -29.01 -52.73, -26.14 APE12-dist-in 8.595 APE11-dist-in 11.809 APE10-dist-in 6.327 APE9-dist-in 4.712 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[13, 275]] 1.0 AF-O43293-K3 CAMK_DAPK3_HUMAN CAMK 8.9e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
1YRPA 2 277 454.0 No_ligand No_ligand Active DFGin 6.736 13.755 BLAminus -134.53, 168.02 67.46, 101.36 -121.14, 21.48 292.51, 79.87 -63.71, -8.91 in-in in 9.21 Saltbr-in 2.51 HRD-in -63.58, -46.12 71.02, -4.0 in-in-in SNCiii in-in ActLoopNT-in 2.903 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.45, 166.65 APE9-dihe-na 98.49, -177.72 APE8-dihe-in -92.21, 127.08 APE8-rot-in 307.54 APE67-dihe-in -53.2, -35.86 -39.66, -46.71 APE12-dist-in 9.541 APE11-dist-in 11.338 APE10-dist-in 5.81 APE9-dist-in 4.578 None TPO265 TPO265 XRAY 3.1 0.245 0.268 A 278 276 0 0 0 0 [[13, 275]] 1.0 1yrp CAMK_DAPK3_HUMAN CAMK 8.7e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
1YRPB 2 277 454.0 No_ligand No_ligand Active DFGin 6.74 13.77 BLAminus -134.26, 167.85 67.06, 101.54 -121.73, 22.3 292.45, 80.16 -64.33, -8.63 in-in in 9.222 Saltbr-in 2.53 HRD-in -63.83, -45.65 70.82, -3.89 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.85, 166.44 APE9-dihe-na 98.86, -176.99 APE8-dihe-in -92.88, 126.22 APE8-rot-in 307.9 APE67-dihe-in -54.47, -35.24 -39.85, -44.93 APE12-dist-in 9.543 APE11-dist-in 11.336 APE10-dist-in 5.806 APE9-dist-in 4.562 None TPO265 TPO265 XRAY 3.1 0.245 0.268 B 278 276 0 0 0 0 [[13, 275]] 1.0 1yrp CAMK_DAPK3_HUMAN CAMK 8.7e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5VJAA 9 277 454.0 DUK:61002 Type1 Active DFGin 6.921 14.411 BLAminus -124.21, 167.93 69.15, 85.7 -98.82, 31.64 285.89, 72.01 -66.28, -27.84 in-in in 9.184 Saltbr-in 2.753 HRD-in -75.5, -47.39 68.94, 0.3 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.18, 178.74 APE9-dihe-na 90.02, -176.89 APE8-dihe-in -101.23, 120.34 APE8-rot-in 301.7 APE67-dihe-in -45.29, -32.43 -40.42, -52.96 APE12-dist-in 8.543 APE11-dist-in 11.913 APE10-dist-in 6.514 APE9-dist-in 4.479 None None None XRAY 2.46 0.19 0.237 A 283 264 5 0 0 0 [[13, 275]] 1.0 5vja CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5VJAB 9 278 454.0 DUK:61002 Type1 Active DFGin 6.902 14.428 BLAminus -123.57, 168.82 69.53, 85.85 -99.43, 30.94 286.28, 72.91 -67.68, -26.05 in-in in 9.22 Saltbr-in 2.735 HRD-in -75.95, -47.94 69.17, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.914 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.45, 178.52 APE9-dihe-na 89.96, -176.86 APE8-dihe-in -102.13, 121.23 APE8-rot-in 300.73 APE67-dihe-in -45.57, -32.05 -40.27, -53.64 APE12-dist-in 8.541 APE11-dist-in 11.916 APE10-dist-in 6.514 APE9-dist-in 4.478 None None None XRAY 2.46 0.19 0.237 B 283 264 6 0 0 0 [[13, 275]] 1.0 5vja CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5VJAC 9 278 454.0 DUK:61002 Type1 Active DFGin 6.978 14.47 BLAminus -125.79, 169.08 71.44, 84.47 -99.06, 30.82 287.63, 73.32 -66.0, -28.44 in-in in 9.402 Saltbr-in 2.709 HRD-in -73.9, -47.63 70.4, -1.19 in-in-in SNCiii in-in ActLoopNT-in 2.914 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.83, 177.52 APE9-dihe-na 90.76, -176.28 APE8-dihe-in -101.02, 120.52 APE8-rot-in 301.36 APE67-dihe-in -45.99, -31.65 -41.76, -53.26 APE12-dist-in 8.552 APE11-dist-in 11.944 APE10-dist-in 6.513 APE9-dist-in 4.42 None None None XRAY 2.46 0.19 0.237 C 283 263 7 0 0 0 [[13, 275]] 1.0 5vja CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5VJAD 9 277 454.0 DUK:60303 Type1 Active DFGin 6.978 14.446 BLAminus -125.49, 168.91 71.14, 84.23 -98.06, 29.74 287.71, 73.43 -66.47, -27.82 in-in in 9.402 Saltbr-in 2.687 HRD-in -74.02, -47.37 69.6, -1.17 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.18, 177.87 APE9-dihe-na 90.89, -176.29 APE8-dihe-in -102.1, 120.9 APE8-rot-in 302.0 APE67-dihe-in -48.83, -30.37 -39.86, -53.06 APE12-dist-in 8.564 APE11-dist-in 11.96 APE10-dist-in 6.524 APE9-dist-in 4.457 None None None XRAY 2.46 0.19 0.237 D 283 259 10 0 0 0 [[13, 275]] 1.0 5vja CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5A6NB 9 278 454.0 No_ligand No_ligand Inactive DFGin 7.134 15.2 BLAminus -123.17, 173.47 71.07, 82.34 -96.31, 23.3 288.14, 80.72 -58.51, -28.15 out-out out 10.214 Saltbr-out 4.598 HRD-in -72.22, -46.82 72.39, -0.62 out-in-out SNCoio in-out ActLoopNT-in 2.938 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -87.08, -23.38 APE9-dihe-na -102.55, -156.89 APE8-dihe-in -67.58, 138.53 APE8-rot-out 177.76 APE67-dihe-in -60.71, -25.29 -87.59, 2.06 APE12-dist-out 20.882 APE11-dist-out 25.895 APE10-dist-out 26.982 APE9-dist-out 32.067 None None None XRAY 1.7 0.184 0.213 B 283 265 5 0 0 5 [[13, 275]] 1.0 5a6n CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5A6OA 9 278 454.0 No_ligand No_ligand Inactive DFGin 7.033 14.927 BLAminus -124.93, 169.84 70.35, 86.0 -95.56, 23.36 289.55, 80.64 -56.9, -30.81 out-out out 10.184 Saltbr-out 4.486 HRD-in -72.53, -47.56 71.73, -5.92 out-in-out SNCoio in-out ActLoopNT-in 2.882 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -86.63, -9.38 APE9-dihe-na 83.56, -65.93 APE8-dihe-in -142.01, 166.97 APE8-rot-out 82.26 APE67-dihe-in -55.96, -35.96 -89.93, 8.42 APE12-dist-out 24.469 APE11-dist-out 21.443 APE10-dist-out 25.117 APE9-dist-out 30.847 None None None XRAY 1.6 0.196 0.225 A 283 265 5 0 0 5 [[13, 275]] 1.0 5a6o CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5A6OB 9 277 454.0 No_ligand No_ligand Inactive DFGin 7.1 15.237 BLAminus -125.92, 173.3 69.72, 85.37 -98.13, 24.03 287.76, 77.63 -63.51, -22.51 out-out out 10.337 Saltbr-out 4.684 HRD-in -70.6, -46.97 70.56, -0.99 out-in-out SNCoio in-out ActLoopNT-in 2.994 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -89.08, -24.35 APE9-dihe-na -103.83, -154.95 APE8-dihe-in -69.39, 139.67 APE8-rot-out 177.29 APE67-dihe-in -59.63, -25.1 -89.19, 2.53 APE12-dist-out 20.751 APE11-dist-out 25.705 APE10-dist-out 26.766 APE9-dist-out 31.83 None None None XRAY 1.6 0.196 0.225 B 283 264 5 0 0 5 [[13, 275]] 1.0 5a6o CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
3BHYA 9 283 454.0 7CP:60600 Type1 Inactive DFGin 6.749 14.682 BLAminus -133.75, 175.73 62.51, 76.51 -93.42, 20.22 284.09, 75.33 -66.97, -19.01 in-in in 9.56 Saltbr-in 3.459 HRD-in -73.3, -44.99 71.01, 1.48 in-in-out SNCiio in-out ActLoopNT-in 2.882 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 114.13 APE9-dihe-na -83.03, -136.0 APE8-dihe-in -93.41, 124.29 APE8-rot-in 304.71 APE67-dihe-in -63.61, -21.19 -42.66, -48.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.554 APE9-dist-in 4.138 None None None XRAY 1.24 0.146 0.187 A 283 267 8 0 0 8 [[13, 275]] 1.0 3bhy CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
3BQRA 9 284 454.0 4RB:60401 Type1 Inactive DFGin 6.772 14.448 BLAminus -129.0, 177.13 61.77, 82.92 -94.67, 24.81 289.64, 85.69 -58.67, -30.81 in-in in 9.47 Saltbr-in 2.643 HRD-in -73.43, -42.99 68.62, 1.05 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -88.95, -36.75 APE9-dihe-na -71.08, 176.2 APE8-dihe-in -62.94, 140.1 APE8-rot-out 177.94 APE67-dihe-in -51.43, -30.04 -88.64, 0.64 APE12-dist-out 28.78 APE11-dist-out 27.902 APE10-dist-out 32.072 APE9-dist-out 33.749 None None None XRAY 1.75 0.181 0.215 A 283 273 3 0 0 3 [[13, 275]] 1.0 3bqr CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
5A6NA 9 278 454.0 U7E:60300 Type1 Inactive DFGin 7.048 14.602 BLAminus -123.51, 170.0 70.79, 84.49 -96.15, 23.93 288.05, 80.88 -59.62, -27.49 in-in in 9.697 Saltbr-in 2.767 HRD-in -72.65, -46.34 71.56, -2.71 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -86.91, -9.32 APE9-dihe-na 83.79, -64.49 APE8-dihe-in -146.28, 164.79 APE8-rot-out 81.48 APE67-dihe-in -52.6, -37.03 -86.36, 5.14 APE12-dist-out 24.682 APE11-dist-out 21.775 APE10-dist-out 25.41 APE9-dist-out 31.042 None None None XRAY 1.7 0.184 0.213 A 283 270 0 0 0 0 [[13, 275]] 1.0 5a6n CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
2J90A 5 278 454.0 IZA:60300 Type1 Inactive DFGin 6.842 14.055 BLAminus -125.3, 179.27 61.44, 82.34 -98.36, 26.77 287.5, 77.69 -60.38, -28.86 in-in in 9.482 Saltbr-in 2.724 HRD-in -74.15, -47.48 72.53, -6.38 in-in-out SNCiio in-out ActLoopNT-in 2.933 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -170.29 APE8-dihe-in -60.3, 135.25 APE8-rot-out 187.21 APE67-dihe-in -56.76, -23.02 -90.5, 3.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.546 None SEP50,TPO265 SEP50,TPO265 XRAY 2.0 0.187 0.222 A 304 265 9 0 0 9 [[13, 275]] 1.0 2j90 CAMK_DAPK3_HUMAN CAMK 1.2e-96 329.0 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
2J90B 12 280 454.0 IZA:60300 Type1 Inactive DFGin 6.972 14.048 BLAminus -120.27, 179.29 63.28, 79.45 -98.26, 31.78 290.61, 80.97 -66.96, -24.76 in-in in 9.277 Saltbr-in 2.522 HRD-in -71.79, -47.75 74.41, -3.27 in-in-out SNCiio in-out ActLoopNT-in 2.99 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -91.89, 0.08 APE9-dihe-na -126.75, -177.65 APE8-dihe-in -67.18, 141.61 APE8-rot-out 176.86 APE67-dihe-in -59.93, -28.41 -88.21, 6.8 APE12-dist-out 27.214 APE11-dist-out 26.973 APE10-dist-out 30.7 APE9-dist-out 33.666 None SEP50,TPO265 SEP50,TPO265 XRAY 2.0 0.187 0.222 B 304 264 5 0 0 0 [[13, 275]] 1.0 2j90 CAMK_DAPK3_HUMAN CAMK 1.2e-96 329.0 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3

CAMK_DAPK3 (Death-associated protein kinase 3)

Total number of chains: 16
Active chains: 8
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 16 100.0% AF-O43293-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
DAPK3_HUMAN AF-O43293-K1A O43293 5 283 454.0 No_ligand No_ligand Active DFGin 6.748 14.044 BLAminus -123.35, 175.18 57.14, 85.1 -91.34, 18.19 285.15, 81.66 -60.32, -31.25 in-in in 9.234 Saltbr-in 2.745 HRD-in -73.32, -40.76 62.86, -13.13 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.45, -179.33 APE9-dihe-na 83.48, 171.43 APE8-dihe-in -83.74, 124.14 APE8-rot-in 298.87 APE67-dihe-in -61.76, -27.25 -48.42, -36.53 APE12-dist-in 8.761 APE11-dist-in 11.759 APE10-dist-in 6.301 APE9-dist-in 5.093 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[13, 275]] 1.0 AF-O43293-K1 Homo sapiens CAMK_DAPK3_HUMAN CAMK 8.9e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN AF-O43293-K3A O43293 5 283 454.0 No_ligand No_ligand Active DFGin 6.714 14.117 BLAminus -125.53, -178.47 52.36, 75.24 -81.75, 15.99 283.01, 81.08 -55.71, -32.68 in-in in 9.322 Saltbr-in 2.723 HRD-in -78.84, -39.96 62.42, -3.08 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.11, -174.39 APE9-dihe-na 82.83, 170.05 APE8-dihe-in -79.78, 124.91 APE8-rot-in 299.59 APE67-dihe-in -71.44, -29.01 -52.73, -26.14 APE12-dist-in 8.595 APE11-dist-in 11.809 APE10-dist-in 6.327 APE9-dist-in 4.712 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[13, 275]] 1.0 AF-O43293-K3 Homo sapiens CAMK_DAPK3_HUMAN CAMK 8.9e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 1YRPA O43293 2 277 454.0 No_ligand No_ligand Active DFGin 6.736 13.755 BLAminus -134.53, 168.02 67.46, 101.36 -121.14, 21.48 292.51, 79.87 -63.71, -8.91 in-in in 9.21 Saltbr-in 2.51 HRD-in -63.58, -46.12 71.02, -4.0 in-in-in SNCiii in-in ActLoopNT-in 2.903 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.45, 166.65 APE9-dihe-na 98.49, -177.72 APE8-dihe-in -92.21, 127.08 APE8-rot-in 307.54 APE67-dihe-in -53.2, -35.86 -39.66, -46.71 APE12-dist-in 9.541 APE11-dist-in 11.338 APE10-dist-in 5.81 APE9-dist-in 4.578 None TPO265 TPO265 XRAY 3.1 0.245 0.268 A 278 276 0 0 0 0 [[13, 275]] 1.0 1yrp Homo sapiens CAMK_DAPK3_HUMAN CAMK 8.7e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 1YRPB O43293 2 277 454.0 No_ligand No_ligand Active DFGin 6.74 13.77 BLAminus -134.26, 167.85 67.06, 101.54 -121.73, 22.3 292.45, 80.16 -64.33, -8.63 in-in in 9.222 Saltbr-in 2.53 HRD-in -63.83, -45.65 70.82, -3.89 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.85, 166.44 APE9-dihe-na 98.86, -176.99 APE8-dihe-in -92.88, 126.22 APE8-rot-in 307.9 APE67-dihe-in -54.47, -35.24 -39.85, -44.93 APE12-dist-in 9.543 APE11-dist-in 11.336 APE10-dist-in 5.806 APE9-dist-in 4.562 None TPO265 TPO265 XRAY 3.1 0.245 0.268 B 278 276 0 0 0 0 [[13, 275]] 1.0 1yrp Homo sapiens CAMK_DAPK3_HUMAN CAMK 8.7e-97 329.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5VJAA O43293 9 277 454.0 DUK:61002 Type1 Active DFGin 6.921 14.411 BLAminus -124.21, 167.93 69.15, 85.7 -98.82, 31.64 285.89, 72.01 -66.28, -27.84 in-in in 9.184 Saltbr-in 2.753 HRD-in -75.5, -47.39 68.94, 0.3 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.18, 178.74 APE9-dihe-na 90.02, -176.89 APE8-dihe-in -101.23, 120.34 APE8-rot-in 301.7 APE67-dihe-in -45.29, -32.43 -40.42, -52.96 APE12-dist-in 8.543 APE11-dist-in 11.913 APE10-dist-in 6.514 APE9-dist-in 4.479 None None None XRAY 2.46 0.19 0.237 A 283 264 5 0 0 0 [[13, 275]] 1.0 5vja Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5VJAB O43293 9 278 454.0 DUK:61002 Type1 Active DFGin 6.902 14.428 BLAminus -123.57, 168.82 69.53, 85.85 -99.43, 30.94 286.28, 72.91 -67.68, -26.05 in-in in 9.22 Saltbr-in 2.735 HRD-in -75.95, -47.94 69.17, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.914 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.45, 178.52 APE9-dihe-na 89.96, -176.86 APE8-dihe-in -102.13, 121.23 APE8-rot-in 300.73 APE67-dihe-in -45.57, -32.05 -40.27, -53.64 APE12-dist-in 8.541 APE11-dist-in 11.916 APE10-dist-in 6.514 APE9-dist-in 4.478 None None None XRAY 2.46 0.19 0.237 B 283 264 6 0 0 0 [[13, 275]] 1.0 5vja Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5VJAC O43293 9 278 454.0 DUK:61002 Type1 Active DFGin 6.978 14.47 BLAminus -125.79, 169.08 71.44, 84.47 -99.06, 30.82 287.63, 73.32 -66.0, -28.44 in-in in 9.402 Saltbr-in 2.709 HRD-in -73.9, -47.63 70.4, -1.19 in-in-in SNCiii in-in ActLoopNT-in 2.914 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.83, 177.52 APE9-dihe-na 90.76, -176.28 APE8-dihe-in -101.02, 120.52 APE8-rot-in 301.36 APE67-dihe-in -45.99, -31.65 -41.76, -53.26 APE12-dist-in 8.552 APE11-dist-in 11.944 APE10-dist-in 6.513 APE9-dist-in 4.42 None None None XRAY 2.46 0.19 0.237 C 283 263 7 0 0 0 [[13, 275]] 1.0 5vja Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5VJAD O43293 9 277 454.0 DUK:60303 Type1 Active DFGin 6.978 14.446 BLAminus -125.49, 168.91 71.14, 84.23 -98.06, 29.74 287.71, 73.43 -66.47, -27.82 in-in in 9.402 Saltbr-in 2.687 HRD-in -74.02, -47.37 69.6, -1.17 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.18, 177.87 APE9-dihe-na 90.89, -176.29 APE8-dihe-in -102.1, 120.9 APE8-rot-in 302.0 APE67-dihe-in -48.83, -30.37 -39.86, -53.06 APE12-dist-in 8.564 APE11-dist-in 11.96 APE10-dist-in 6.524 APE9-dist-in 4.457 None None None XRAY 2.46 0.19 0.237 D 283 259 10 0 0 0 [[13, 275]] 1.0 5vja Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5A6NB O43293 9 278 454.0 No_ligand No_ligand Inactive DFGin 7.134 15.2 BLAminus -123.17, 173.47 71.07, 82.34 -96.31, 23.3 288.14, 80.72 -58.51, -28.15 out-out out 10.214 Saltbr-out 4.598 HRD-in -72.22, -46.82 72.39, -0.62 out-in-out SNCoio in-out ActLoopNT-in 2.938 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -87.08, -23.38 APE9-dihe-na -102.55, -156.89 APE8-dihe-in -67.58, 138.53 APE8-rot-out 177.76 APE67-dihe-in -60.71, -25.29 -87.59, 2.06 APE12-dist-out 20.882 APE11-dist-out 25.895 APE10-dist-out 26.982 APE9-dist-out 32.067 None None None XRAY 1.7 0.184 0.213 B 283 265 5 0 0 5 [[13, 275]] 1.0 5a6n Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5A6OA O43293 9 278 454.0 No_ligand No_ligand Inactive DFGin 7.033 14.927 BLAminus -124.93, 169.84 70.35, 86.0 -95.56, 23.36 289.55, 80.64 -56.9, -30.81 out-out out 10.184 Saltbr-out 4.486 HRD-in -72.53, -47.56 71.73, -5.92 out-in-out SNCoio in-out ActLoopNT-in 2.882 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -86.63, -9.38 APE9-dihe-na 83.56, -65.93 APE8-dihe-in -142.01, 166.97 APE8-rot-out 82.26 APE67-dihe-in -55.96, -35.96 -89.93, 8.42 APE12-dist-out 24.469 APE11-dist-out 21.443 APE10-dist-out 25.117 APE9-dist-out 30.847 None None None XRAY 1.6 0.196 0.225 A 283 265 5 0 0 5 [[13, 275]] 1.0 5a6o Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5A6OB O43293 9 277 454.0 No_ligand No_ligand Inactive DFGin 7.1 15.237 BLAminus -125.92, 173.3 69.72, 85.37 -98.13, 24.03 287.76, 77.63 -63.51, -22.51 out-out out 10.337 Saltbr-out 4.684 HRD-in -70.6, -46.97 70.56, -0.99 out-in-out SNCoio in-out ActLoopNT-in 2.994 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -89.08, -24.35 APE9-dihe-na -103.83, -154.95 APE8-dihe-in -69.39, 139.67 APE8-rot-out 177.29 APE67-dihe-in -59.63, -25.1 -89.19, 2.53 APE12-dist-out 20.751 APE11-dist-out 25.705 APE10-dist-out 26.766 APE9-dist-out 31.83 None None None XRAY 1.6 0.196 0.225 B 283 264 5 0 0 5 [[13, 275]] 1.0 5a6o Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 3BHYA O43293 9 283 454.0 7CP:60600 Type1 Inactive DFGin 6.749 14.682 BLAminus -133.75, 175.73 62.51, 76.51 -93.42, 20.22 284.09, 75.33 -66.97, -19.01 in-in in 9.56 Saltbr-in 3.459 HRD-in -73.3, -44.99 71.01, 1.48 in-in-out SNCiio in-out ActLoopNT-in 2.882 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 114.13 APE9-dihe-na -83.03, -136.0 APE8-dihe-in -93.41, 124.29 APE8-rot-in 304.71 APE67-dihe-in -63.61, -21.19 -42.66, -48.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.554 APE9-dist-in 4.138 None None None XRAY 1.24 0.146 0.187 A 283 267 8 0 0 8 [[13, 275]] 1.0 3bhy Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 3BQRA O43293 9 284 454.0 4RB:60401 Type1 Inactive DFGin 6.772 14.448 BLAminus -129.0, 177.13 61.77, 82.92 -94.67, 24.81 289.64, 85.69 -58.67, -30.81 in-in in 9.47 Saltbr-in 2.643 HRD-in -73.43, -42.99 68.62, 1.05 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -88.95, -36.75 APE9-dihe-na -71.08, 176.2 APE8-dihe-in -62.94, 140.1 APE8-rot-out 177.94 APE67-dihe-in -51.43, -30.04 -88.64, 0.64 APE12-dist-out 28.78 APE11-dist-out 27.902 APE10-dist-out 32.072 APE9-dist-out 33.749 None None None XRAY 1.75 0.181 0.215 A 283 273 3 0 0 3 [[13, 275]] 1.0 3bqr Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 5A6NA O43293 9 278 454.0 U7E:60300 Type1 Inactive DFGin 7.048 14.602 BLAminus -123.51, 170.0 70.79, 84.49 -96.15, 23.93 288.05, 80.88 -59.62, -27.49 in-in in 9.697 Saltbr-in 2.767 HRD-in -72.65, -46.34 71.56, -2.71 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -86.91, -9.32 APE9-dihe-na 83.79, -64.49 APE8-dihe-in -146.28, 164.79 APE8-rot-out 81.48 APE67-dihe-in -52.6, -37.03 -86.36, 5.14 APE12-dist-out 24.682 APE11-dist-out 21.775 APE10-dist-out 25.41 APE9-dist-out 31.042 None None None XRAY 1.7 0.184 0.213 A 283 270 0 0 0 0 [[13, 275]] 1.0 5a6n Homo sapiens CAMK_DAPK3_HUMAN CAMK 9.4e-97 329.2 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 2J90A O43293 5 278 454.0 IZA:60300 Type1 Inactive DFGin 6.842 14.055 BLAminus -125.3, 179.27 61.44, 82.34 -98.36, 26.77 287.5, 77.69 -60.38, -28.86 in-in in 9.482 Saltbr-in 2.724 HRD-in -74.15, -47.48 72.53, -6.38 in-in-out SNCiio in-out ActLoopNT-in 2.933 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -170.29 APE8-dihe-in -60.3, 135.25 APE8-rot-out 187.21 APE67-dihe-in -56.76, -23.02 -90.5, 3.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.546 None SEP50,TPO265 SEP50,TPO265 XRAY 2.0 0.187 0.222 A 304 265 9 0 0 9 [[13, 275]] 1.0 2j90 Homo sapiens CAMK_DAPK3_HUMAN CAMK 1.2e-96 329.0 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3
DAPK3_HUMAN 2J90B O43293 12 280 454.0 IZA:60300 Type1 Inactive DFGin 6.972 14.048 BLAminus -120.27, 179.29 63.28, 79.45 -98.26, 31.78 290.61, 80.97 -66.96, -24.76 in-in in 9.277 Saltbr-in 2.522 HRD-in -71.79, -47.75 74.41, -3.27 in-in-out SNCiio in-out ActLoopNT-in 2.99 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -91.89, 0.08 APE9-dihe-na -126.75, -177.65 APE8-dihe-in -67.18, 141.61 APE8-rot-out 176.86 APE67-dihe-in -59.93, -28.41 -88.21, 6.8 APE12-dist-out 27.214 APE11-dist-out 26.973 APE10-dist-out 30.7 APE9-dist-out 33.666 None SEP50,TPO265 SEP50,TPO265 XRAY 2.0 0.187 0.222 B 304 264 5 0 0 0 [[13, 275]] 1.0 2j90 Homo sapiens CAMK_DAPK3_HUMAN CAMK 1.2e-96 329.0 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 3

CAMK_DAPK3 (Death-associated protein kinase 3)

Total number of chains: 0
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name