CK1_CSNK1D (Casein kinase I isoform delta)

Total number of chains: 120
Active chains: 84
Family: CK1
Uniprot: KC1D_HUMAN
Kinase Domain Residues: 9 - 275
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 120 100.0% AF-P48730-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
6RU6A 3 294 415.0 ACP:60301 ATPlike Active DFGin 6.436 15.264 BLAminus -136.56, 176.84 69.53, 73.53 -93.66, 24.95 289.84, 81.36 -61.77, -30.96 in-in in 7.923 Saltbr-in 2.789 HRD-in -77.83, -55.12 76.08, 12.52 in-in-in SNCiii in-in ActLoopNT-in 2.85 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.64, 119.59 APE9-dihe-na 102.6, -136.74 APE8-dihe-in -117.46, 127.27 APE8-rot-in 311.09 APE67-dihe-in -57.82, -37.85 -53.66, -47.41 APE12-dist-in 12.315 APE11-dist-in 11.908 APE10-dist-in 6.481 APE9-dist-in 3.505 None None None XRAY 2.05 0.213 0.257 A 296 288 4 0 0 0 [[9, 275]] 1.0 6ru6 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7FA 3 294 415.0 AMP:305 ATPlike Active DFGin 6.386 14.989 BLAminus -135.41, 179.24 65.29, 82.6 -99.51, 20.86 287.48, 77.77 -56.63, -36.85 in-in in 8.099 Saltbr-in 2.591 HRD-in -82.17, -51.93 74.76, 11.47 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.01, 118.96 APE9-dihe-na 109.81, -163.5 APE8-dihe-in -91.97, 119.49 APE8-rot-in 320.94 APE67-dihe-in -55.9, -38.32 -51.55, -37.41 APE12-dist-in 13.114 APE11-dist-in 12.585 APE10-dist-in 6.845 APE9-dist-in 3.948 None TPO220 TPO220 XRAY 1.96 0.19 0.221 A 296 292 0 0 0 0 [[9, 275]] 1.0 7p7f CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7FB 3 294 415.0 AMP:310 ATPlike Active DFGin 6.389 15.041 BLAminus -134.9, -178.65 62.6, 84.78 -99.93, 21.19 288.23, 78.97 -57.89, -34.16 in-in in 8.117 Saltbr-in 2.593 HRD-in -86.23, -54.05 76.65, 11.34 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.84, 118.88 APE9-dihe-na 108.83, -162.51 APE8-dihe-in -93.95, 118.29 APE8-rot-in 320.41 APE67-dihe-in -55.93, -38.53 -50.49, -37.42 APE12-dist-in 13.14 APE11-dist-in 12.546 APE10-dist-in 6.804 APE9-dist-in 4.014 None TPO220 TPO220 XRAY 1.96 0.19 0.221 B 296 292 0 0 0 0 [[9, 275]] 1.0 7p7f CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7HA 3 294 415.0 AMP:301 ATPlike Active DFGin 5.85 14.904 BLAminus -131.69, 175.32 69.71, 86.46 -98.17, 29.2 291.07, 84.43 -61.3, -36.51 in-in in 8.328 Saltbr-in 2.869 HRD-in -85.02, -56.99 74.97, 14.35 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.26, -19.24 APE9-dihe-na -88.34, -159.24 APE8-dihe-in -92.63, 127.36 APE8-rot-in 313.8 APE67-dihe-in -57.88, -32.21 -74.29, -29.96 APE12-dist-in 10.816 APE11-dist-in 12.399 APE10-dist-in 6.988 APE9-dist-in 4.101 None None None XRAY 2.4 0.225 0.268 A 296 292 0 0 0 0 [[9, 275]] 1.0 7p7h CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7HB 3 294 415.0 AMP:301 ATPlike Active DFGin 5.843 14.916 BLAminus -130.5, 174.9 69.57, 86.72 -100.58, 28.91 292.34, 82.14 -57.01, -35.01 in-in in 8.325 Saltbr-in 2.918 HRD-in -84.55, -57.9 81.6, 9.08 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.93, 49.41 APE9-dihe-na 140.08, -131.01 APE8-dihe-in -99.84, 119.2 APE8-rot-in 321.52 APE67-dihe-in -56.55, -33.9 -75.78, -27.7 APE12-dist-in 12.421 APE11-dist-in 12.165 APE10-dist-in 7.215 APE9-dist-in 4.736 None None None XRAY 2.4 0.225 0.268 B 296 292 0 0 0 0 [[9, 275]] 1.0 7p7h CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
AF-P48730-K1A 1 283 415.0 No_ligand No_ligand Active DFGin 6.014 14.738 BLAminus -133.52, 176.85 64.1, 66.27 -77.63, 11.73 293.67, 97.86 -60.56, -26.09 in-in in 8.117 Saltbr-in 2.685 HRD-in -76.86, -43.78 66.27, -7.2 in-in-in SNCiii in-in ActLoopNT-in 2.829 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.58, 134.54 APE9-dihe-na 97.48, -176.89 APE8-dihe-in -80.26, 109.12 APE8-rot-in 301.44 APE67-dihe-in -58.05, -41.24 -50.16, -30.35 APE12-dist-in 12.286 APE11-dist-in 12.4 APE10-dist-in 6.762 APE9-dist-in 3.559 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[9, 275]] 1.0 AF-P48730-K1 CK1_CSNK1D_HUMAN CK1 1.3e-122 414.1 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
AF-P48730-K3A 1 283 415.0 No_ligand No_ligand Active DFGin 6.036 14.99 BLAminus -135.79, -179.69 65.66, 57.84 -74.43, 9.28 295.07, 110.08 -61.57, -21.47 in-in in 8.244 Saltbr-in 2.688 HRD-in -75.16, -44.32 68.95, -5.99 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.24, 137.17 APE9-dihe-na 87.75, -172.14 APE8-dihe-in -81.8, 106.79 APE8-rot-in 298.65 APE67-dihe-in -57.57, -40.66 -46.21, -33.58 APE12-dist-in 12.33 APE11-dist-in 12.46 APE10-dist-in 6.972 APE9-dist-in 3.344 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[9, 275]] 1.0 AF-P48730-K3 CK1_CSNK1D_HUMAN CK1 1.3e-122 414.1 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RCHB 1 293 415.0 No_ligand No_ligand Active DFGin 5.843 14.557 BLAminus -131.65, 170.96 76.64, 96.11 -104.66, 20.03 292.76, 102.3 -66.03, -25.81 in-in in 7.929 Saltbr-in 2.638 HRD-in -82.16, -49.05 70.48, 10.61 in-in-in SNCiii in-in ActLoopNT-in 2.87 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -103.36, -16.93 APE9-dihe-na -91.24, -146.45 APE8-dihe-in -101.75, 113.83 APE8-rot-in 306.19 APE67-dihe-in -56.37, -33.25 -58.53, -38.11 APE12-dist-in 12.316 APE11-dist-in 12.015 APE10-dist-in 7.0 APE9-dist-in 4.335 None None None XRAY 1.45 0.157 0.178 B 296 293 0 0 0 0 [[9, 275]] 1.0 6rch CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYSA 4 294 415.0 No_ligand No_ligand Active DFGin 6.102 15.072 BLAminus -135.99, -172.72 54.24, 84.3 -98.01, 23.68 285.73, 116.84 -62.69, -28.36 in-in in 8.356 Saltbr-in 2.611 HRD-in -83.32, -46.5 68.28, 7.86 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.95, 102.73 APE9-dihe-na 151.96, -149.32 APE8-dihe-in -118.11, 114.68 APE8-rot-in 297.33 APE67-dihe-in -67.47, -40.27 -52.12, -24.47 APE12-dist-in 13.143 APE11-dist-in 12.267 APE10-dist-in 6.813 APE9-dist-in 4.11 None None None XRAY 2.3 0.238 0.276 A 296 281 10 0 0 0 [[9, 275]] 1.0 3uys CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYSB 4 294 415.0 No_ligand No_ligand Active DFGin 6.122 15.305 BLAminus -123.48, -176.29 49.64, 104.5 -109.98, 26.53 290.32, 65.97 -66.14, -7.64 in-in in 8.686 Saltbr-in 2.902 HRD-in -63.12, -39.01 58.16, 15.19 in-in-in SNCiii in-in ActLoopNT-in 3.005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.51, 106.93 APE9-dihe-na 146.4, -128.36 APE8-dihe-in -129.25, 128.0 APE8-rot-in 311.95 APE67-dihe-in -54.57, -43.47 -56.45, -39.42 APE12-dist-in 12.939 APE11-dist-in 11.871 APE10-dist-in 6.445 APE9-dist-in 4.15 None None None XRAY 2.3 0.238 0.276 B 296 279 12 0 0 0 [[9, 275]] 1.0 3uys CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYSC 4 294 415.0 No_ligand No_ligand Active DFGin 6.17 14.989 BLAminus -134.31, -179.28 58.1, 91.57 -102.86, 27.33 288.56, 103.71 -68.45, -23.02 in-in in 8.167 Saltbr-in 3.006 HRD-in -74.66, -53.28 79.91, 5.21 in-in-in SNCiii in-in ActLoopNT-in 3.101 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.65, 112.01 APE9-dihe-na 135.42, -174.74 APE8-dihe-in -92.63, 117.69 APE8-rot-in 318.84 APE67-dihe-in -76.69, -30.13 -57.91, -14.76 APE12-dist-in 12.529 APE11-dist-in 12.063 APE10-dist-in 6.4 APE9-dist-in 3.903 None None None XRAY 2.3 0.238 0.276 C 296 286 5 0 0 4 [[9, 275]] 1.0 3uys CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYSD 4 294 415.0 No_ligand No_ligand Active DFGin 5.978 14.973 BLAminus -135.58, 176.18 66.3, 85.15 -100.12, 27.44 287.44, 108.47 -71.4, -34.89 in-in in 8.26 Saltbr-in 2.909 HRD-in -74.17, -45.77 69.63, -6.25 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.44, 116.33 APE9-dihe-na 132.39, -162.25 APE8-dihe-in -97.61, 129.12 APE8-rot-in 319.85 APE67-dihe-in -65.73, -32.75 -68.54, -21.24 APE12-dist-in 12.774 APE11-dist-in 12.098 APE10-dist-in 6.503 APE9-dist-in 4.271 None None None XRAY 2.3 0.238 0.276 D 296 284 7 0 0 0 [[9, 275]] 1.0 3uys CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7MB 2 290 415.0 No_ligand No_ligand Active DFGin 6.366 15.054 BLAminus -133.02, 176.99 67.05, 83.52 -99.86, 23.87 288.55, 76.27 -66.65, -21.08 in-in in 7.994 Saltbr-in 2.747 HRD-in -83.86, -50.81 73.21, 7.48 in-in-in SNCiii in-in ActLoopNT-in 2.918 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.04, 138.78 APE9-dihe-na 100.9, -144.49 APE8-dihe-in -113.42, 133.79 APE8-rot-in 286.18 APE67-dihe-in -68.47, -33.95 -60.62, -36.47 APE12-dist-in 12.874 APE11-dist-in 12.443 APE10-dist-in 7.065 APE9-dist-in 3.614 None None None XRAY 2.25 0.183 0.233 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7m CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7OB 2 290 415.0 No_ligand No_ligand Active DFGin 6.707 14.954 BLAminus -129.86, -179.93 67.27, 80.46 -100.25, 21.82 286.61, 77.74 -67.58, -21.13 in-in in 8.052 Saltbr-in 2.827 HRD-in -85.94, -49.67 73.0, 5.76 in-in-in SNCiii in-in ActLoopNT-in 2.848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.84, 136.91 APE9-dihe-na 109.35, -145.96 APE8-dihe-in -119.11, 136.0 APE8-rot-in 295.77 APE67-dihe-in -64.5, -36.47 -59.05, -40.84 APE12-dist-in 13.253 APE11-dist-in 12.2 APE10-dist-in 6.908 APE9-dist-in 3.455 None None None XRAY 1.65 0.174 0.209 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7o CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7PB 2 290 415.0 No_ligand No_ligand Active DFGin 5.859 14.67 BLAminus -130.49, 172.66 68.65, 91.76 -101.03, 25.87 297.23, 90.22 -72.86, -19.19 in-in in 8.015 Saltbr-in 2.456 HRD-in -85.55, -52.52 74.69, 6.14 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.07, 117.73 APE9-dihe-na -149.93, -159.97 APE8-dihe-in -104.9, 114.63 APE8-rot-in 293.84 APE67-dihe-in -64.02, -31.31 -56.89, -40.01 APE12-dist-in 13.303 APE11-dist-in 10.243 APE10-dist-in 7.565 APE9-dist-in 4.675 None None None XRAY 2.25 0.199 0.251 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7p CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TN6B 2 292 415.0 No_ligand No_ligand Active DFGin 6.047 14.793 BLAminus -131.93, 175.74 67.68, 89.2 -98.57, 20.63 293.04, 101.16 -63.36, -31.28 in-in in 8.009 Saltbr-in 2.892 HRD-in -77.62, -48.19 67.28, 6.53 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.84, 98.76 APE9-dihe-na 123.78, -164.81 APE8-dihe-in -90.48, 131.01 APE8-rot-in 310.94 APE67-dihe-in -53.03, -41.99 -58.19, -43.36 APE12-dist-in 11.393 APE11-dist-in 11.652 APE10-dist-in 6.054 APE9-dist-in 3.92 None None None XRAY 2.41 0.19 0.239 B 318 285 3 0 0 0 [[9, 275]] 1.0 4tn6 CK1_CSNK1D_HUMAN CK1 2e-122 413.5 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXPA 2 293 415.0 No_ligand No_ligand Active DFGin 5.983 14.851 BLAminus -137.52, 172.85 65.52, 95.22 -107.76, 25.56 291.17, 109.72 -73.49, -24.5 in-in in 8.254 Saltbr-in 2.912 HRD-in -81.44, -47.41 77.01, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.57, 122.69 APE9-dihe-na 111.56, 179.84 APE8-dihe-in -78.24, 136.92 APE8-rot-in 308.99 APE67-dihe-in -60.53, -35.81 -68.97, -29.32 APE12-dist-in 10.48 APE11-dist-in 11.788 APE10-dist-in 6.065 APE9-dist-in 3.705 K171E None None XRAY 2.35 0.201 0.243 A 294 288 4 0 0 0 [[9, 275]] 1.0 6pxp CK1_CSNK1D_HUMAN CK1 4.4e-122 412.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8IZCB 5 294 415.0 S93:60303 Type1 Active DFGin 5.795 15.13 BLAminus -127.75, 168.53 74.17, 99.03 -107.93, 19.19 290.65, 101.85 -62.94, -27.99 in-in in 8.485 Saltbr-in 3.369 HRD-in -80.22, -50.17 74.11, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -104.14, 152.75 APE9-dihe-na 103.35, -169.22 APE8-dihe-in -99.98, 119.89 APE8-rot-in 309.34 APE67-dihe-in -53.04, -39.2 -57.61, -35.96 APE12-dist-in 11.953 APE11-dist-in 12.011 APE10-dist-in 6.408 APE9-dist-in 3.978 None None None XRAY 1.45 0.192 0.207 B 291 290 0 0 0 0 [[9, 275]] 1.0 8izc CK1_CSNK1D_HUMAN CK1 1.5e-122 414.0 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5IH6A 2 293 415.0 AUG:305 Type1 Active DFGin 5.9 15.482 BLAminus -128.7, 171.19 73.47, 91.55 -103.56, 28.82 292.29, 98.11 -73.23, -29.86 in-in in 8.572 Saltbr-in 3.419 HRD-in -87.62, -49.57 76.35, -3.83 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.33, 137.88 APE9-dihe-na 98.97, -178.76 APE8-dihe-in -78.42, 134.27 APE8-rot-in 320.15 APE67-dihe-in -51.8, -40.15 -63.26, -37.67 APE12-dist-in 12.526 APE11-dist-in 11.843 APE10-dist-in 6.114 APE9-dist-in 3.84 None None None XRAY 2.3 0.234 0.26 A 294 286 6 0 0 0 [[9, 275]] 1.0 5ih6 CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7FC 4 294 415.0 ADN:307 Type1 Active DFGin 6.287 14.774 BLAminus -127.27, 170.02 72.27, 90.59 -100.52, 22.08 289.81, 85.32 -63.29, -31.3 in-in in 7.933 Saltbr-in 2.63 HRD-in -80.78, -51.31 76.2, 11.32 in-in-in SNCiii in-in ActLoopNT-in 2.918 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.83, -40.42 APE9-dihe-na -88.08, -154.15 APE8-dihe-in -92.07, 119.61 APE8-rot-in 316.8 APE67-dihe-in -56.43, -36.06 -56.0, -37.52 APE12-dist-in 12.693 APE11-dist-in 12.117 APE10-dist-in 6.391 APE9-dist-in 4.324 None TPO220 TPO220 XRAY 1.96 0.19 0.221 C 296 285 6 0 0 6 [[9, 275]] 1.0 7p7f CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7FD 4 294 415.0 ADN:309 Type1 Active DFGin 6.224 14.767 BLAminus -126.64, 169.11 73.89, 91.36 -99.69, 21.56 289.8, 84.96 -66.02, -29.96 in-in in 7.952 Saltbr-in 2.667 HRD-in -81.57, -51.69 78.22, 8.75 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.24, -37.1 APE9-dihe-na -85.95, -158.82 APE8-dihe-in -90.13, 119.34 APE8-rot-in 319.47 APE67-dihe-in -54.92, -36.79 -58.02, -35.64 APE12-dist-in 13.37 APE11-dist-in 12.222 APE10-dist-in 6.519 APE9-dist-in 4.362 None TPO220 TPO220 XRAY 1.96 0.19 0.221 D 296 285 6 0 0 6 [[9, 275]] 1.0 7p7f CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QR9B 2 294 415.0 EZQ:304 Type1 Active DFGin 5.736 15.259 BLAminus -137.93, 175.93 70.34, 95.42 -112.76, 22.31 285.98, 104.42 -71.79, -20.33 in-in in 8.494 Saltbr-in 3.033 HRD-in -85.88, -57.56 74.9, 13.35 in-in-in SNCiii in-in ActLoopNT-in 3.121 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.3, 111.05 APE9-dihe-na 138.52, -161.09 APE8-dihe-in -99.08, 116.92 APE8-rot-in 313.8 APE67-dihe-in -61.25, -36.96 -59.19, -34.06 APE12-dist-in 12.385 APE11-dist-in 12.095 APE10-dist-in 6.629 APE9-dist-in 4.19 None None None XRAY 2.3 0.254 0.305 B 296 291 2 0 0 0 [[9, 275]] 1.0 7qr9 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRAA 3 294 415.0 EYI:307 Type1 Active DFGin 5.739 15.212 BLAminus -129.63, 174.95 73.0, 97.71 -116.41, 24.77 288.45, 102.87 -71.56, -22.75 in-in in 8.527 Saltbr-in 2.784 HRD-in -85.23, -60.7 76.19, 18.85 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -82.29, -40.65 APE9-dihe-na -87.45, -140.73 APE8-dihe-in -96.68, 126.6 APE8-rot-in 315.63 APE67-dihe-in -60.1, -39.91 -69.45, -28.12 APE12-dist-in 12.097 APE11-dist-in 12.053 APE10-dist-in 6.433 APE9-dist-in 3.891 None None None XRAY 2.4 0.241 0.282 A 296 289 3 0 0 0 [[9, 275]] 1.0 7qra CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRAB 3 294 415.0 EYI:308 Type1 Active DFGin 5.764 15.183 BLAminus -130.87, 174.1 72.72, 98.11 -115.7, 24.4 288.11, 100.43 -70.38, -23.64 in-in in 8.561 Saltbr-in 2.768 HRD-in -84.79, -60.13 77.89, 15.35 in-in-in SNCiii in-in ActLoopNT-in 2.965 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.51, -41.22 APE9-dihe-na -87.16, -142.78 APE8-dihe-in -95.48, 126.32 APE8-rot-in 317.4 APE67-dihe-in -62.31, -40.0 -66.85, -28.92 APE12-dist-in 12.377 APE11-dist-in 12.072 APE10-dist-in 6.452 APE9-dist-in 3.944 None None None XRAY 2.4 0.241 0.282 B 296 289 3 0 0 0 [[9, 275]] 1.0 7qra CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRAC 3 294 415.0 EYI:305 Type1 Active DFGin 5.844 15.171 BLAminus -126.88, 173.42 75.27, 97.85 -115.56, 23.0 289.2, 100.23 -73.01, -21.24 in-in in 8.536 Saltbr-in 2.851 HRD-in -84.69, -59.53 80.0, 13.31 in-in-in SNCiii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.55, 110.63 APE9-dihe-na 137.63, -156.44 APE8-dihe-in -96.52, 125.23 APE8-rot-in 317.11 APE67-dihe-in -61.28, -38.81 -74.42, -24.35 APE12-dist-in 13.448 APE11-dist-in 12.036 APE10-dist-in 6.428 APE9-dist-in 4.257 None None None XRAY 2.4 0.241 0.282 C 296 280 12 0 0 9 [[9, 275]] 1.0 7qra CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRAD 3 294 415.0 EYI:304 Type1 Active DFGin 5.888 15.199 BLAminus -125.88, 173.32 76.1, 97.96 -116.31, 23.64 289.96, 100.23 -73.22, -20.1 in-in in 8.622 Saltbr-in 2.839 HRD-in -83.39, -59.49 80.05, 13.06 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.71, 111.44 APE9-dihe-na 139.23, -155.32 APE8-dihe-in -97.46, 125.75 APE8-rot-in 316.99 APE67-dihe-in -61.28, -37.47 -73.02, -28.07 APE12-dist-in 13.411 APE11-dist-in 11.996 APE10-dist-in 6.435 APE9-dist-in 4.231 None None None XRAY 2.4 0.241 0.282 D 296 280 12 0 0 9 [[9, 275]] 1.0 7qra CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRBA 3 294 415.0 EX9:303 Type1 Active DFGin 5.786 14.749 BLAminus -138.57, 173.71 74.23, 97.05 -111.52, 23.54 292.13, 96.9 -64.17, -33.44 in-in in 8.054 Saltbr-in 3.32 HRD-in -80.6, -62.98 85.02, 10.42 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.53, -38.97 APE9-dihe-na -79.34, -143.1 APE8-dihe-in -104.26, 120.14 APE8-rot-in 303.67 APE67-dihe-in -58.5, -38.92 -56.29, -38.68 APE12-dist-in 11.569 APE11-dist-in 12.023 APE10-dist-in 6.479 APE9-dist-in 3.619 None None None XRAY 2.6 0.231 0.273 A 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRBB 3 294 415.0 EX9:304 Type1 Active DFGin 5.864 14.858 BLAminus -136.87, 171.91 74.6, 98.93 -112.49, 24.79 293.01, 96.72 -66.73, -32.74 in-in in 8.061 Saltbr-in 3.313 HRD-in -79.65, -62.36 86.77, 5.68 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.7, -39.26 APE9-dihe-na -82.5, -142.47 APE8-dihe-in -103.22, 119.83 APE8-rot-in 303.38 APE67-dihe-in -57.15, -38.6 -56.04, -38.93 APE12-dist-in 11.587 APE11-dist-in 11.936 APE10-dist-in 6.251 APE9-dist-in 3.66 None None None XRAY 2.6 0.231 0.273 B 296 286 6 0 0 6 [[9, 275]] 1.0 7qrb CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRBC 3 294 415.0 EX9:304 Type1 Active DFGin 5.83 14.833 BLAminus -136.6, 172.53 75.75, 98.41 -112.93, 24.4 292.54, 96.74 -63.85, -34.66 in-in in 8.075 Saltbr-in 3.337 HRD-in -77.66, -63.11 86.68, 6.65 in-in-in SNCiii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.13, -39.43 APE9-dihe-na -82.01, -141.99 APE8-dihe-in -104.01, 120.43 APE8-rot-in 304.37 APE67-dihe-in -57.15, -38.63 -55.0, -40.36 APE12-dist-in 11.611 APE11-dist-in 11.922 APE10-dist-in 6.301 APE9-dist-in 3.646 None None None XRAY 2.6 0.231 0.273 C 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QRBD 3 294 415.0 EX9:304 Type1 Active DFGin 5.848 14.758 BLAminus -138.94, 173.09 73.42, 97.56 -112.5, 24.45 292.46, 98.28 -63.82, -34.18 in-in in 8.054 Saltbr-in 3.317 HRD-in -78.8, -62.72 85.13, 9.67 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.2, -41.31 APE9-dihe-na -85.0, -140.82 APE8-dihe-in -103.74, 120.37 APE8-rot-in 302.04 APE67-dihe-in -59.1, -39.29 -54.22, -40.17 APE12-dist-in 11.758 APE11-dist-in 12.03 APE10-dist-in 6.411 APE9-dist-in 3.551 None None None XRAY 2.6 0.231 0.273 D 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYTA 5 294 415.0 0CK:295 Type1 Active DFGin 5.914 14.938 BLAminus -141.08, 175.99 67.87, 107.54 -117.55, 28.27 290.71, 107.29 -70.97, -30.55 in-in in 8.507 Saltbr-in 2.578 HRD-in -69.52, -53.91 74.76, 11.3 in-in-in SNCiii in-in ActLoopNT-in 2.99 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.54, 92.6 APE9-dihe-na 157.25, -156.27 APE8-dihe-in -105.18, 125.66 APE8-rot-in 309.98 APE67-dihe-in -52.24, -36.38 -55.43, -45.0 APE12-dist-in 12.286 APE11-dist-in 11.403 APE10-dist-in 5.737 APE9-dist-in 3.605 None None None XRAY 2.0 0.244 0.264 A 296 287 3 0 0 0 [[9, 275]] 1.0 3uyt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYTB 5 293 415.0 0CK:295 Type1 Active DFGin 5.42 14.466 BLAminus -143.78, 172.36 63.44, 117.05 -123.51, 20.44 290.83, 101.94 -64.96, -18.67 in-in in 8.367 Saltbr-in 2.945 HRD-in -78.34, -51.59 77.34, 0.24 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.63, 92.97 APE9-dihe-na 149.06, -156.59 APE8-dihe-in -100.96, 114.13 APE8-rot-in 309.57 APE67-dihe-in -57.69, -42.62 -43.66, -38.84 APE12-dist-in 12.886 APE11-dist-in 11.92 APE10-dist-in 6.378 APE9-dist-in 4.155 None None None XRAY 2.0 0.244 0.264 B 296 286 3 0 0 0 [[9, 275]] 1.0 3uyt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYTC 4 294 415.0 0CK:295 Type1 Active DFGin 5.532 15.483 BLAminus -138.61, 175.24 64.91, 102.33 -113.46, 24.22 289.92, 94.05 -63.01, -34.95 in-in in 8.62 Saltbr-in 3.217 HRD-in -72.73, -40.93 68.45, -2.11 in-in-in SNCiii in-in ActLoopNT-in 3.078 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.52, 137.99 APE9-dihe-na 115.79, -168.26 APE8-dihe-in -90.1, 119.0 APE8-rot-in 305.56 APE67-dihe-in -66.15, -27.91 -51.09, -29.22 APE12-dist-in 11.702 APE11-dist-in 11.708 APE10-dist-in 5.903 APE9-dist-in 3.838 None None None XRAY 2.0 0.244 0.264 C 296 286 5 0 0 5 [[9, 275]] 1.0 3uyt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UZPA 3 294 415.0 0CK:295 Type1 Active DFGin 5.661 14.832 BLAminus -134.7, 173.74 69.19, 94.06 -102.81, 19.82 288.11, 111.94 -54.7, -37.81 in-in in 8.555 Saltbr-in 2.607 HRD-in -74.71, -48.25 74.53, -1.72 in-in-in SNCiii in-in ActLoopNT-in 2.938 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.7, 101.99 APE9-dihe-na 139.12, -156.68 APE8-dihe-in -102.2, 123.58 APE8-rot-in 298.11 APE67-dihe-in -52.36, -37.32 -50.21, -43.05 APE12-dist-in 12.672 APE11-dist-in 11.791 APE10-dist-in 6.402 APE9-dist-in 3.527 None None None XRAY 1.94 0.222 0.237 A 296 292 0 0 0 0 [[9, 275]] 1.0 3uzp CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UZPB 3 294 415.0 0CK:295 Type1 Active DFGin 5.908 15.464 BLAminus -139.62, -179.78 62.23, 101.11 -114.8, 18.24 283.45, 104.48 -58.48, -26.44 in-in in 9.492 Saltbr-in 3.594 HRD-in -70.0, -50.75 77.55, -9.13 in-in-in SNCiii in-in ActLoopNT-in 2.867 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.19, 122.16 APE9-dihe-na 123.24, -159.55 APE8-dihe-in -115.76, 127.13 APE8-rot-in 299.41 APE67-dihe-in -56.38, -38.46 -53.95, -40.13 APE12-dist-in 11.194 APE11-dist-in 11.725 APE10-dist-in 6.221 APE9-dist-in 3.676 None None None XRAY 1.94 0.222 0.237 B 296 284 8 0 0 0 [[9, 275]] 1.0 3uzp CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4HGTB 2 292 415.0 15G:301 Type1 Active DFGin 5.952 14.705 BLAminus -132.84, 173.91 65.29, 88.38 -100.07, 21.04 283.75, 100.66 -60.36, -23.77 in-in in 7.949 Saltbr-in 2.937 HRD-in -80.87, -49.33 71.68, 6.17 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.78, 107.2 APE9-dihe-na 146.92, -145.17 APE8-dihe-in -124.2, 122.26 APE8-rot-in 267.86 APE67-dihe-in -56.15, -40.08 -47.18, -38.14 APE12-dist-in 11.727 APE11-dist-in 12.247 APE10-dist-in 6.687 APE9-dist-in 3.634 None None None XRAY 1.8 0.24 999.0 B 296 280 11 0 0 0 [[9, 275]] 1.0 4hgt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4HNFA 3 294 415.0 16W:301 Type1 Active DFGin 6.575 15.804 BLAminus -129.62, -172.35 54.61, 82.41 -100.04, 26.99 293.51, 69.72 -59.68, -32.76 in-in in 8.617 Saltbr-in 3.254 HRD-in -66.07, -51.92 76.62, -0.09 in-in-in SNCiii in-in ActLoopNT-in 3.142 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 21.82 APE9-dihe-na -154.45, -143.25 APE8-dihe-in -85.78, 141.82 APE8-rot-in 301.59 APE67-dihe-in -65.11, -35.21 -83.43, -20.7 APE12-dist-in 13.022 APE11-dist-in 12.366 APE10-dist-in 7.147 APE9-dist-in 4.202 None None None XRAY 2.07 0.241 0.274 A 296 289 3 0 0 0 [[9, 275]] 1.0 4hnf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8VXFA 4 298 415.0 A1AD8:301 Type1 Active DFGin 5.913 14.514 BLAminus -129.71, -178.22 61.03, 74.13 -90.6, 25.58 297.09, 127.44 -66.39, -39.14 in-in in 8.04 Saltbr-in 2.628 HRD-in -70.13, -47.31 64.93, 7.47 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.9, 115.78 APE9-dihe-na 125.37, 178.72 APE8-dihe-in -73.6, 131.81 APE8-rot-in 292.64 APE67-dihe-in -59.57, -36.01 -65.35, -39.56 APE12-dist-in 10.879 APE11-dist-in 11.888 APE10-dist-in 6.111 APE9-dist-in 3.896 None None CSO71 XRAY 2.28 0.228 0.271 A 300 290 5 0 0 0 [[9, 275]] 1.0 8vxf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8VXFB 1 293 415.0 A1AD8:301 Type1 Active DFGin 6.1 14.996 BLAminus -135.43, 179.54 60.46, 71.85 -84.36, 20.57 294.99, 103.53 -64.07, -35.46 in-in in 7.944 Saltbr-in 2.702 HRD-in -73.22, -53.58 69.54, 9.3 in-in-in SNCiii in-in ActLoopNT-in 2.736 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -87.76, 115.91 APE9-dihe-na 129.1, -158.3 APE8-dihe-in -97.01, 130.38 APE8-rot-in 323.35 APE67-dihe-in -60.35, -42.07 -72.75, -30.86 APE12-dist-in 11.43 APE11-dist-in 12.092 APE10-dist-in 6.268 APE9-dist-in 4.473 None None None XRAY 2.28 0.228 0.271 B 300 288 5 0 0 0 [[9, 275]] 1.0 8vxf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVB 8 294 415.0 D5Q:301 Type1 Active DFGin 5.737 14.961 BLAminus -131.59, 168.24 73.3, 96.74 -107.44, 22.04 293.08, 97.39 -64.43, -25.64 in-in in 8.317 Saltbr-in 2.794 HRD-in -81.79, -49.07 72.49, 10.59 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.51, 119.45 APE9-dihe-na 118.74, -165.96 APE8-dihe-in -84.66, 139.43 APE8-rot-in 317.86 APE67-dihe-in -59.35, -40.52 -71.07, -35.78 APE12-dist-in 12.332 APE11-dist-in 11.984 APE10-dist-in 6.359 APE9-dist-in 4.004 None None None XRAY 2.154 0.173 0.192 B 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVD 8 294 415.0 D5Q:301 Type1 Active DFGin 5.649 14.92 BLAminus -130.27, 169.09 73.19, 96.34 -107.09, 21.82 293.69, 97.37 -65.13, -25.84 in-in in 8.321 Saltbr-in 2.828 HRD-in -81.65, -48.96 71.89, 10.75 in-in-in SNCiii in-in ActLoopNT-in 2.898 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.39, -36.96 APE9-dihe-na -78.91, -162.23 APE8-dihe-in -81.37, 139.78 APE8-rot-in 305.31 APE67-dihe-in -59.04, -40.2 -68.84, -34.55 APE12-dist-in 11.976 APE11-dist-in 11.838 APE10-dist-in 6.137 APE9-dist-in 3.591 None None None XRAY 2.154 0.173 0.192 D 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVE 8 294 415.0 D5Q:301 Type1 Active DFGin 5.791 14.918 BLAminus -131.33, 167.82 73.19, 96.43 -108.05, 21.28 293.17, 96.99 -65.15, -25.25 in-in in 8.304 Saltbr-in 2.81 HRD-in -81.43, -48.77 72.2, 11.06 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.94, 80.73 APE9-dihe-na 158.19, -165.3 APE8-dihe-in -84.27, 138.68 APE8-rot-in 301.84 APE67-dihe-in -58.32, -40.17 -70.07, -35.1 APE12-dist-in 12.322 APE11-dist-in 11.724 APE10-dist-in 6.16 APE9-dist-in 3.977 None None None XRAY 2.154 0.173 0.192 E 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5OKTA 4 294 415.0 9XK:301 Type1 Active DFGin 6.162 14.659 BLAminus -133.28, 170.74 70.01, 89.31 -99.0, 19.37 294.41, 97.23 -61.59, -31.32 in-in in 8.04 Saltbr-in 2.927 HRD-in -77.86, -49.22 74.22, 0.79 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.17, 82.01 APE9-dihe-na 156.53, -168.77 APE8-dihe-in -81.75, 134.56 APE8-rot-in 311.88 APE67-dihe-in -58.69, -40.95 -68.59, -35.26 APE12-dist-in 12.888 APE11-dist-in 12.07 APE10-dist-in 6.617 APE9-dist-in 3.899 None TPO220 TPO220 XRAY 2.13 0.194 0.221 A 314 286 5 0 0 5 [[9, 275]] 1.0 5okt CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5OKTC 4 294 415.0 9XK:301 Type1 Active DFGin 6.083 14.872 BLAminus -137.28, 172.91 70.72, 87.04 -99.3, 19.0 294.7, 94.59 -62.74, -31.92 in-in in 8.117 Saltbr-in 2.573 HRD-in -77.69, -49.38 74.02, -0.1 in-in-in SNCiii in-in ActLoopNT-in 2.849 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.15, 136.58 APE9-dihe-na 93.44, -169.87 APE8-dihe-in -82.53, 136.41 APE8-rot-in 312.32 APE67-dihe-in -57.5, -41.07 -68.78, -35.33 APE12-dist-in 12.445 APE11-dist-in 12.119 APE10-dist-in 6.693 APE9-dist-in 3.421 None None None XRAY 2.13 0.194 0.221 C 314 285 6 0 0 0 [[9, 275]] 1.0 5okt CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5OKTD 3 294 415.0 9XK:301 Type1 Active DFGin 6.062 14.744 BLAminus -137.52, 172.23 70.39, 87.93 -98.16, 19.61 294.71, 94.98 -62.25, -31.9 in-in in 8.107 Saltbr-in 2.861 HRD-in -77.53, -49.31 73.84, 0.69 in-in-in SNCiii in-in ActLoopNT-in 2.822 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.67, 126.53 APE9-dihe-na 102.05, -168.99 APE8-dihe-in -81.94, 134.78 APE8-rot-in 312.39 APE67-dihe-in -57.6, -41.02 -69.15, -35.23 APE12-dist-in 12.39 APE11-dist-in 12.149 APE10-dist-in 6.705 APE9-dist-in 3.71 None None None XRAY 2.13 0.194 0.221 D 314 282 10 0 0 0 [[9, 275]] 1.0 5okt CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6F1WA 3 292 415.0 CG5:308 Type1 Active DFGin 5.617 15.345 BLAminus -131.72, 170.95 75.82, 94.85 -108.5, 22.63 294.72, 95.1 -64.52, -24.91 in-in in 9.034 Saltbr-in 3.495 HRD-in -79.29, -50.31 74.39, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -107.6, 102.07 APE9-dihe-na 145.81, -161.66 APE8-dihe-in -102.55, 122.91 APE8-rot-in 308.33 APE67-dihe-in -56.46, -36.56 -57.9, -38.78 APE12-dist-in 11.928 APE11-dist-in 11.655 APE10-dist-in 6.007 APE9-dist-in 3.737 None TPO220 TPO220 XRAY 1.864 0.182 0.206 A 314 285 5 0 0 0 [[9, 275]] 1.0 6f1w CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6F1WB 1 291 415.0 CG5:309 Type1 Active DFGin 5.64 15.419 BLAminus -133.14, 170.48 75.33, 95.98 -108.41, 23.26 294.11, 96.58 -64.58, -24.61 in-in in 9.202 Saltbr-in 3.422 HRD-in -79.25, -49.88 75.06, 6.23 in-in-in SNCiii in-in ActLoopNT-in 2.85 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.07, 103.05 APE9-dihe-na 146.18, -161.66 APE8-dihe-in -103.19, 123.14 APE8-rot-in 307.68 APE67-dihe-in -56.96, -36.58 -57.24, -38.6 APE12-dist-in 12.077 APE11-dist-in 11.827 APE10-dist-in 6.192 APE9-dist-in 3.705 None None None XRAY 1.864 0.182 0.206 B 314 280 11 0 0 0 [[9, 275]] 1.0 6f1w CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6F26A 3 293 415.0 C9Z:314 Type1 Active DFGin 5.759 15.483 BLAminus -132.42, 172.37 74.42, 91.28 -106.08, 19.87 292.81, 96.43 -64.71, -22.22 in-in in 9.087 Saltbr-in 3.426 HRD-in -79.24, -49.47 75.74, 5.24 in-in-in SNCiii in-in ActLoopNT-in 2.843 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.38, 102.1 APE9-dihe-na 153.19, -157.67 APE8-dihe-in -110.24, 124.98 APE8-rot-in 305.28 APE67-dihe-in -58.18, -34.02 -57.89, -38.29 APE12-dist-in 11.56 APE11-dist-in 11.694 APE10-dist-in 5.991 APE9-dist-in 3.545 None None None XRAY 1.83 0.19 0.209 A 314 280 11 0 0 0 [[9, 275]] 1.0 6f26 CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6F26B 3 293 415.0 C9Z:307 Type1 Active DFGin 5.658 15.526 BLAminus -131.85, 172.58 74.83, 92.21 -105.55, 19.73 292.1, 96.5 -64.53, -21.81 in-in in 9.286 Saltbr-in 3.199 HRD-in -79.15, -49.63 75.68, 5.29 in-in-in SNCiii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.91, 102.25 APE9-dihe-na 153.59, -157.23 APE8-dihe-in -110.24, 124.2 APE8-rot-in 305.62 APE67-dihe-in -58.5, -35.79 -58.44, -37.5 APE12-dist-in 11.609 APE11-dist-in 11.683 APE10-dist-in 6.003 APE9-dist-in 3.574 None None None XRAY 1.83 0.19 0.209 B 314 281 10 0 0 0 [[9, 275]] 1.0 6f26 CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6HMPA 8 294 415.0 GEW:301 Type1 Active DFGin 5.852 14.825 BLAminus -132.93, 168.87 75.84, 99.76 -110.81, 21.42 294.49, 101.21 -61.62, -29.55 in-in in 8.336 Saltbr-in 2.749 HRD-in -83.25, -49.35 75.12, 6.17 in-in-in SNCiii in-in ActLoopNT-in 2.812 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.37, 137.14 APE9-dihe-na 102.67, -169.04 APE8-dihe-in -88.64, 128.2 APE8-rot-in 309.71 APE67-dihe-in -55.63, -40.75 -60.69, -38.48 APE12-dist-in 12.788 APE11-dist-in 12.341 APE10-dist-in 6.674 APE9-dist-in 3.818 None None None XRAY 2.039 0.187 0.219 A 314 286 1 0 0 0 [[9, 275]] 1.0 6hmp CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6HMPB 1 293 415.0 GEW:301 Type1 Active DFGin 5.703 14.778 BLAminus -133.94, 168.26 76.06, 99.73 -110.46, 21.48 293.68, 101.03 -62.95, -28.85 in-in in 8.204 Saltbr-in 2.664 HRD-in -81.34, -48.98 74.24, 7.39 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.0, 132.29 APE9-dihe-na 101.61, -168.87 APE8-dihe-in -87.9, 130.96 APE8-rot-in 309.49 APE67-dihe-in -55.04, -40.56 -59.88, -37.12 APE12-dist-in 11.739 APE11-dist-in 11.823 APE10-dist-in 6.199 APE9-dist-in 3.617 None None None XRAY 2.039 0.187 0.219 B 314 278 15 0 0 0 [[9, 275]] 1.0 6hmp CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6HMRA 7 294 415.0 GE5:60301 Type1 Active DFGin 5.902 14.826 BLAminus -129.77, 165.39 78.39, 101.15 -107.5, 20.0 293.32, 102.36 -64.81, -25.32 in-in in 8.284 Saltbr-in 2.749 HRD-in -83.07, -49.96 76.13, 7.49 in-in-in SNCiii in-in ActLoopNT-in 2.825 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -105.61, 123.18 APE9-dihe-na 112.73, -152.95 APE8-dihe-in -99.78, 125.38 APE8-rot-in 305.84 APE67-dihe-in -55.81, -38.54 -61.27, -36.97 APE12-dist-in 12.625 APE11-dist-in 12.31 APE10-dist-in 6.77 APE9-dist-in 3.973 None None None XRAY 1.782 0.176 0.199 A 314 287 1 0 0 0 [[9, 275]] 1.0 6hmr CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6HMRB 1 293 415.0 GE5:60301 Type1 Active DFGin 5.728 14.821 BLAminus -132.18, 166.65 79.25, 99.25 -107.58, 20.5 292.42, 101.79 -65.16, -22.71 in-in in 8.173 Saltbr-in 2.632 HRD-in -83.94, -50.09 75.09, 8.55 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.7, -50.27 APE9-dihe-na -84.81, -142.78 APE8-dihe-in -93.52, 127.66 APE8-rot-in 306.5 APE67-dihe-in -55.61, -39.37 -59.1, -37.12 APE12-dist-in 12.085 APE11-dist-in 11.829 APE10-dist-in 6.028 APE9-dist-in 3.927 None None None XRAY 1.782 0.176 0.199 B 314 279 14 0 0 0 [[9, 275]] 1.0 6hmr CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7NZYA 4 294 415.0 UX2:301 Type1 Active DFGin 6.559 14.886 BLAminus -133.96, 167.79 70.83, 96.95 -106.29, 25.68 291.55, 83.04 -66.18, -24.86 in-in in 8.075 Saltbr-in 3.016 HRD-in -78.9, -49.6 75.24, 4.27 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.05, -40.09 APE9-dihe-na -82.1, -153.64 APE8-dihe-in -93.91, 137.61 APE8-rot-in 310.79 APE67-dihe-in -56.87, -39.19 -67.48, -35.89 APE12-dist-in 12.805 APE11-dist-in 11.473 APE10-dist-in 5.963 APE9-dist-in 3.855 None TPO220 TPO220 XRAY 1.85 0.205 0.229 A 314 286 5 0 0 5 [[9, 275]] 1.0 7nzy CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7NZYC 3 294 415.0 UX2:301 Type1 Active DFGin 6.218 14.791 BLAminus -136.64, 167.98 72.37, 97.2 -107.4, 23.39 293.87, 95.12 -65.21, -24.66 in-in in 8.1 Saltbr-in 2.77 HRD-in -79.48, -51.87 75.69, 7.23 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -107.57, 101.78 APE9-dihe-na 127.22, -154.68 APE8-dihe-in -96.66, 135.72 APE8-rot-in 310.5 APE67-dihe-in -59.23, -39.9 -66.83, -34.06 APE12-dist-in 12.38 APE11-dist-in 11.857 APE10-dist-in 6.483 APE9-dist-in 3.779 None TPO220 TPO220 XRAY 1.85 0.205 0.229 C 314 283 9 0 0 0 [[9, 275]] 1.0 7nzy CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7NZYD 3 294 415.0 UX2:301 Type1 Active DFGin 6.464 14.937 BLAminus -138.25, 167.9 72.5, 98.99 -108.83, 24.01 292.41, 92.73 -66.77, -25.48 in-in in 8.132 Saltbr-in 2.824 HRD-in -79.6, -51.19 75.63, 6.47 in-in-in SNCiii in-in ActLoopNT-in 2.817 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.03, 112.87 APE9-dihe-na 117.74, -155.19 APE8-dihe-in -96.88, 133.52 APE8-rot-in 309.51 APE67-dihe-in -57.81, -40.27 -67.41, -34.56 APE12-dist-in 12.598 APE11-dist-in 12.323 APE10-dist-in 6.762 APE9-dist-in 3.921 None TPO220 TPO220 XRAY 1.85 0.205 0.229 D 314 285 7 0 0 0 [[9, 275]] 1.0 7nzy CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBCA 2 293 415.0 1QJ:401 Type1 Active DFGin 6.144 15.135 BLAminus -135.05, 177.16 64.97, 92.79 -104.57, 19.94 289.19, 98.91 -62.1, -27.64 in-in in 8.602 Saltbr-in 3.125 HRD-in -76.21, -47.92 72.55, 1.87 in-in-in SNCiii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.96, 99.19 APE9-dihe-na 142.25, -165.38 APE8-dihe-in -94.12, 126.6 APE8-rot-in 308.27 APE67-dihe-in -52.38, -38.16 -56.17, -42.26 APE12-dist-in 11.369 APE11-dist-in 11.684 APE10-dist-in 5.988 APE9-dist-in 3.794 None None None XRAY 1.98 0.186 0.215 A 317 288 4 0 0 0 [[9, 275]] 1.0 4kbc CK1_CSNK1D_HUMAN CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBCB 1 291 415.0 1QJ:401 Type1 Active DFGin 6.234 14.815 BLAminus -134.33, 176.57 61.14, 97.98 -105.5, 17.63 290.56, 99.02 -63.05, -28.6 in-in in 8.028 Saltbr-in 2.783 HRD-in -76.33, -48.22 73.21, 2.14 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.52, 104.52 APE9-dihe-na 134.47, -165.32 APE8-dihe-in -95.88, 127.1 APE8-rot-in 306.97 APE67-dihe-in -51.8, -38.48 -58.36, -41.31 APE12-dist-in 11.805 APE11-dist-in 11.967 APE10-dist-in 6.401 APE9-dist-in 3.807 None None None XRAY 1.98 0.186 0.215 B 317 277 11 0 0 0 [[9, 275]] 1.0 4kbc CK1_CSNK1D_HUMAN CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TN6A 2 293 415.0 PFO:401 Type1 Active DFGin 5.994 14.999 BLAminus -131.86, 176.23 68.13, 89.84 -98.73, 20.71 292.85, 102.42 -60.06, -32.67 in-in in 8.564 Saltbr-in 3.478 HRD-in -77.93, -48.08 67.27, 5.51 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.37, 100.66 APE9-dihe-na 124.79, -165.82 APE8-dihe-in -87.49, 129.31 APE8-rot-in 310.24 APE67-dihe-in -53.32, -42.74 -57.19, -41.79 APE12-dist-in 11.521 APE11-dist-in 11.595 APE10-dist-in 6.051 APE9-dist-in 3.859 None None None XRAY 2.41 0.19 0.239 A 318 292 0 0 0 0 [[9, 275]] 1.0 4tn6 CK1_CSNK1D_HUMAN CK1 2e-122 413.5 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TW9A 2 295 415.0 386:1010 Type1 Active DFGin 6.697 14.583 BLAminus -136.97, 175.66 62.22, 78.84 -97.46, 44.93 290.89, 111.01 -92.15, -19.29 in-in in 7.996 Saltbr-in 2.389 HRD-in -80.17, -50.66 73.37, -1.23 in-in-in SNCiii in-in ActLoopNT-in 2.784 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.1, 128.87 APE9-dihe-na 98.06, 169.96 APE8-dihe-in -77.13, 124.79 APE8-rot-in 325.52 APE67-dihe-in -48.58, -35.63 -42.76, -54.19 APE12-dist-in 11.915 APE11-dist-in 11.774 APE10-dist-in 6.514 APE9-dist-in 3.619 R13N None None XRAY 2.4 0.21 0.298 A 295 290 4 0 0 0 [[9, 275]] 1.0 4tw9 CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TW9B 1 295 415.0 386:1007 Type1 Active DFGin 6.721 14.492 BLAminus -131.65, 171.29 75.31, 83.03 -107.11, 28.16 296.33, 79.52 -70.97, -25.3 in-in in 7.827 Saltbr-in 2.545 HRD-in -75.47, -49.16 73.76, 6.22 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.99, 118.4 APE9-dihe-na 97.98, 177.61 APE8-dihe-in -69.71, 139.17 APE8-rot-in 303.41 APE67-dihe-in -54.9, -35.25 -78.5, -33.85 APE12-dist-in 12.475 APE11-dist-in 11.674 APE10-dist-in 6.451 APE9-dist-in 3.592 R13N None None XRAY 2.4 0.21 0.298 B 295 289 6 0 0 0 [[9, 275]] 1.0 4tw9 CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TWCA 2 295 415.0 37J:1007 Type1 Active DFGin 5.789 14.614 BLAminus -135.4, 171.43 74.73, 98.94 -108.48, 20.23 290.12, 99.35 -60.18, -25.97 in-in in 8.185 Saltbr-in 2.802 HRD-in -80.26, -49.62 74.67, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.85, 127.15 APE9-dihe-na 100.6, 178.11 APE8-dihe-in -77.16, 129.65 APE8-rot-in 307.18 APE67-dihe-in -54.54, -41.21 -56.81, -38.63 APE12-dist-in 12.174 APE11-dist-in 11.858 APE10-dist-in 6.354 APE9-dist-in 3.502 R13N None None XRAY 1.7 0.165 0.205 A 295 293 1 0 0 0 [[9, 275]] 1.0 4twc CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4TWCB 1 295 415.0 37J:1008 Type1 Active DFGin 6.186 14.647 BLAminus -137.25, 168.94 78.2, 99.05 -108.33, 17.1 288.71, 108.96 -59.97, -32.8 in-in in 8.033 Saltbr-in 2.803 HRD-in -77.54, -49.39 71.05, 0.74 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.24, 128.18 APE9-dihe-na 92.69, -176.23 APE8-dihe-in -79.0, 129.98 APE8-rot-in 306.66 APE67-dihe-in -54.91, -40.74 -63.37, -37.19 APE12-dist-in 12.252 APE11-dist-in 11.648 APE10-dist-in 6.316 APE9-dist-in 3.571 R13N None None XRAY 1.7 0.165 0.205 B 295 292 3 0 0 0 [[9, 275]] 1.0 4twc CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6GZMB 1 295 415.0 LCI:1003 Type1 Active DFGin 6.029 14.94 BLAminus -133.71, 166.42 75.71, 96.43 -105.56, 19.57 289.87, 100.18 -66.61, -26.34 in-in in 8.2 Saltbr-in 2.978 HRD-in -81.5, -50.17 76.38, 3.88 in-in-in SNCiii in-in ActLoopNT-in 2.885 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.67, 144.06 APE9-dihe-na 111.45, -147.04 APE8-dihe-in -123.08, 119.05 APE8-rot-in 301.33 APE67-dihe-in -54.27, -40.27 -57.58, -37.53 APE12-dist-in 11.578 APE11-dist-in 12.532 APE10-dist-in 6.467 APE9-dist-in 3.981 R13N None None XRAY 1.59 0.192 0.25 B 295 295 0 0 0 0 [[9, 275]] 1.0 6gzm CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KB8B 3 293 415.0 1QO:401 Type1 Active DFGin 5.967 14.913 BLAminus -134.33, 177.52 61.96, 98.8 -107.18, 20.23 290.65, 100.47 -61.53, -33.77 in-in in 8.219 Saltbr-in 2.844 HRD-in -73.63, -48.77 75.48, -5.09 in-in-in SNCiii in-in ActLoopNT-in 2.927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.58, 107.53 APE9-dihe-na 136.09, -158.34 APE8-dihe-in -103.95, 128.43 APE8-rot-in 304.04 APE67-dihe-in -53.87, -40.76 -52.99, -42.94 APE12-dist-in 11.513 APE11-dist-in 11.86 APE10-dist-in 6.123 APE9-dist-in 3.572 None None None XRAY 1.95 0.207 0.232 B 331 285 6 0 0 0 [[9, 275]] 1.0 4kb8 CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KB8C 7 293 415.0 1QN:401 Type1 Active DFGin 5.968 14.825 BLAminus -127.94, 175.57 64.97, 98.7 -108.35, 19.36 290.2, 100.79 -61.94, -33.27 in-in in 8.245 Saltbr-in 2.856 HRD-in -75.11, -48.96 76.7, -5.84 in-in-in SNCiii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.1, 109.67 APE9-dihe-na 130.48, -159.04 APE8-dihe-in -102.61, 128.45 APE8-rot-in 304.06 APE67-dihe-in -54.95, -40.0 -54.23, -41.49 APE12-dist-in 11.374 APE11-dist-in 11.832 APE10-dist-in 6.157 APE9-dist-in 3.556 None None None XRAY 1.95 0.207 0.232 C 331 277 10 0 0 10 [[9, 275]] 1.0 4kb8 CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KB8D 3 293 415.0 1QO:401 Type1 Active DFGin 5.976 14.883 BLAminus -137.08, 175.26 62.92, 98.03 -106.78, 19.33 290.69, 100.97 -61.01, -34.47 in-in in 8.219 Saltbr-in 2.83 HRD-in -73.79, -47.9 74.68, -5.6 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.75, 105.76 APE9-dihe-na 137.74, -159.08 APE8-dihe-in -102.58, 128.72 APE8-rot-in 303.15 APE67-dihe-in -54.52, -40.24 -53.18, -41.69 APE12-dist-in 11.982 APE11-dist-in 11.913 APE10-dist-in 6.189 APE9-dist-in 3.587 None None None XRAY 1.95 0.207 0.232 D 331 278 13 0 0 3 [[9, 275]] 1.0 4kb8 CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBAB 3 293 415.0 1QM:401 Type1 Active DFGin 5.881 14.872 BLAminus -129.74, 173.49 62.39, 106.5 -115.95, 19.82 290.11, 105.76 -62.08, -34.97 in-in in 8.231 Saltbr-in 2.765 HRD-in -71.85, -51.41 76.93, -3.35 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.73, 105.33 APE9-dihe-na 138.05, -162.68 APE8-dihe-in -99.65, 127.15 APE8-rot-in 303.86 APE67-dihe-in -59.88, -40.85 -56.13, -36.41 APE12-dist-in 11.4 APE11-dist-in 11.655 APE10-dist-in 6.019 APE9-dist-in 3.523 None None None XRAY 1.98 0.21 0.237 B 331 285 6 0 0 0 [[9, 275]] 1.0 4kba CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBAC 7 293 415.0 1QM:401 Type1 Active DFGin 5.934 14.746 BLAminus -127.94, 172.81 65.26, 104.02 -113.85, 19.72 291.07, 106.01 -63.19, -33.18 in-in in 7.993 Saltbr-in 2.711 HRD-in -73.02, -52.06 78.99, -4.92 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.53, 105.58 APE9-dihe-na 138.04, -161.96 APE8-dihe-in -100.6, 126.19 APE8-rot-in 304.81 APE67-dihe-in -58.93, -39.59 -56.36, -37.06 APE12-dist-in 11.703 APE11-dist-in 11.719 APE10-dist-in 6.02 APE9-dist-in 3.541 None None None XRAY 1.98 0.21 0.237 C 331 277 10 0 0 10 [[9, 275]] 1.0 4kba CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBAD 3 293 415.0 1QM:401 Type1 Active DFGin 5.906 14.856 BLAminus -129.34, 172.61 62.47, 106.14 -113.79, 20.2 290.42, 106.77 -61.94, -35.25 in-in in 8.227 Saltbr-in 2.847 HRD-in -72.46, -51.24 77.53, -4.45 in-in-in SNCiii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.9, 105.19 APE9-dihe-na 137.57, -162.53 APE8-dihe-in -99.78, 126.75 APE8-rot-in 303.64 APE67-dihe-in -59.4, -40.4 -55.75, -36.15 APE12-dist-in 11.687 APE11-dist-in 11.762 APE10-dist-in 6.101 APE9-dist-in 3.538 None None None XRAY 1.98 0.21 0.237 D 331 274 17 0 0 7 [[9, 275]] 1.0 4kba CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBKA 3 293 415.0 1QG:401 Type1 Active DFGin 5.844 14.976 BLAminus -131.67, 175.29 64.95, 97.7 -105.98, 20.74 289.68, 102.64 -60.84, -32.86 in-in in 8.386 Saltbr-in 2.915 HRD-in -79.36, -48.84 76.24, -1.03 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.11, 44.14 APE9-dihe-na -164.81, -162.01 APE8-dihe-in -83.41, 128.52 APE8-rot-in 306.95 APE67-dihe-in -54.65, -40.65 -56.32, -40.55 APE12-dist-in 11.982 APE11-dist-in 11.806 APE10-dist-in 6.374 APE9-dist-in 3.651 None None None XRAY 2.1 0.193 0.225 A 331 283 8 0 0 0 [[9, 275]] 1.0 4kbk CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBKB 3 293 415.0 1QG:401 Type1 Active DFGin 5.87 14.907 BLAminus -130.17, 174.94 66.33, 98.19 -106.72, 21.44 289.55, 101.16 -63.29, -31.57 in-in in 8.368 Saltbr-in 2.965 HRD-in -71.92, -49.63 76.82, -1.31 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.91, 121.45 APE9-dihe-na 106.7, -175.66 APE8-dihe-in -76.31, 127.18 APE8-rot-in 313.52 APE67-dihe-in -54.93, -40.02 -57.76, -39.93 APE12-dist-in 12.291 APE11-dist-in 12.01 APE10-dist-in 6.338 APE9-dist-in 3.745 None None None XRAY 2.1 0.193 0.225 B 331 289 2 0 0 2 [[9, 275]] 1.0 4kbk CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBKC 4 293 415.0 1QG:401 Type1 Active DFGin 5.855 14.967 BLAminus -129.85, 175.61 65.46, 97.52 -106.96, 21.33 289.98, 100.83 -62.95, -31.03 in-in in 8.373 Saltbr-in 2.945 HRD-in -72.81, -49.86 76.81, -1.6 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -97.84, 118.02 APE9-dihe-na 109.84, -172.07 APE8-dihe-in -80.07, 126.56 APE8-rot-in 311.91 APE67-dihe-in -53.2, -40.67 -57.15, -41.1 APE12-dist-in 12.141 APE11-dist-in 11.935 APE10-dist-in 6.407 APE9-dist-in 3.77 None None None XRAY 2.1 0.193 0.225 C 331 280 10 0 0 7 [[9, 275]] 1.0 4kbk CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5W4WA 3 293 415.0 9WG:4001 Type1 Active DFGin 5.986 15.195 BLAminus -131.25, 176.25 64.66, 92.1 -102.54, 20.05 287.74, 100.7 -63.95, -24.57 in-in in 8.427 Saltbr-in 2.856 HRD-in -71.78, -50.33 73.01, 0.22 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.58, 102.08 APE9-dihe-na 131.12, -154.11 APE8-dihe-in -101.21, 128.13 APE8-rot-in 305.7 APE67-dihe-in -58.83, -38.87 -58.35, -35.99 APE12-dist-in 11.551 APE11-dist-in 11.882 APE10-dist-in 6.338 APE9-dist-in 3.665 None None None XRAY 1.99 0.181 0.215 A 331 291 0 0 0 0 [[9, 275]] 1.0 5w4w CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5W4WB 3 293 415.0 9WG:4001 Type1 Active DFGin 5.978 15.223 BLAminus -131.04, 176.44 64.42, 92.61 -102.67, 20.2 288.33, 100.31 -65.39, -24.22 in-in in 8.487 Saltbr-in 2.794 HRD-in -73.43, -49.34 72.38, -0.15 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.22, 101.23 APE9-dihe-na 132.31, -153.66 APE8-dihe-in -102.36, 127.37 APE8-rot-in 304.5 APE67-dihe-in -57.1, -37.55 -57.06, -37.79 APE12-dist-in 11.602 APE11-dist-in 11.913 APE10-dist-in 6.346 APE9-dist-in 3.698 None None None XRAY 1.99 0.181 0.215 B 331 291 0 0 0 0 [[9, 275]] 1.0 5w4w CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5W4WC 4 293 415.0 9WG:401 Type1 Active DFGin 6.004 15.045 BLAminus -128.72, 177.08 64.84, 92.61 -103.51, 20.15 288.9, 99.1 -59.9, -30.22 in-in in 8.603 Saltbr-in 3.148 HRD-in -73.53, -49.07 71.4, 1.6 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.5, 101.03 APE9-dihe-na 131.64, -155.27 APE8-dihe-in -102.5, 129.0 APE8-rot-in 305.66 APE67-dihe-in -57.12, -38.65 -59.6, -37.26 APE12-dist-in 11.459 APE11-dist-in 11.894 APE10-dist-in 6.335 APE9-dist-in 3.663 None None None XRAY 1.99 0.181 0.215 C 331 284 6 0 0 6 [[9, 275]] 1.0 5w4w CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5W4WD 3 293 415.0 9WG:401 Type1 Active DFGin 6.025 15.044 BLAminus -129.0, 176.14 65.59, 93.67 -104.32, 19.97 289.61, 99.52 -64.71, -24.69 in-in in 8.489 Saltbr-in 2.933 HRD-in -70.95, -50.23 72.86, 1.67 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.11, 101.9 APE9-dihe-na 139.4, -155.09 APE8-dihe-in -103.26, 128.82 APE8-rot-in 306.45 APE67-dihe-in -58.65, -38.27 -59.32, -36.51 APE12-dist-in 11.213 APE11-dist-in 11.863 APE10-dist-in 6.064 APE9-dist-in 3.683 None None None XRAY 1.99 0.181 0.215 D 331 287 4 0 0 0 [[9, 275]] 1.0 5w4w CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RCHA 2 294 415.0 K0B:310 Type1.5_Back Active DFGin 6.035 14.468 BLAminus -122.24, 159.67 82.29, 109.19 -106.33, 18.46 287.11, 119.74 -68.96, -18.8 in-in in 7.785 Saltbr-in 2.655 HRD-in -82.67, -47.67 69.74, 14.2 in-in-in SNCiii in-in ActLoopNT-in 2.847 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -106.54, -51.03 APE9-dihe-na -92.71, -155.88 APE8-dihe-in -77.58, 125.49 APE8-rot-in 293.15 APE67-dihe-in -52.81, -38.11 -57.21, -30.67 APE12-dist-in 11.686 APE11-dist-in 11.749 APE10-dist-in 5.801 APE9-dist-in 3.993 None None None XRAY 1.45 0.157 0.178 A 296 293 0 0 0 0 [[9, 275]] 1.0 6rch CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU7A 3 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.392 15.125 BLAminus -134.23, -173.24 59.44, 80.86 -96.06, 22.96 285.76, 78.27 -62.92, -27.34 in-in in 7.971 Saltbr-in 2.803 HRD-in -82.18, -50.23 72.61, 5.15 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.24, 126.6 APE9-dihe-na 114.96, -145.11 APE8-dihe-in -115.28, 122.22 APE8-rot-in 302.31 APE67-dihe-in -56.73, -38.36 -50.64, -46.9 APE12-dist-in 12.381 APE11-dist-in 12.179 APE10-dist-in 6.834 APE9-dist-in 3.511 None None None XRAY 2.08 0.177 0.218 A 296 292 0 0 0 0 [[9, 275]] 1.0 6ru7 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU7B 3 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.618 14.988 BLAminus -130.01, -176.4 60.72, 81.81 -97.28, 21.17 286.1, 78.89 -61.41, -29.58 in-in in 7.795 Saltbr-in 2.912 HRD-in -81.31, -50.84 72.75, 6.38 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.97, 131.36 APE9-dihe-na 113.79, -145.67 APE8-dihe-in -115.43, 125.17 APE8-rot-in 305.08 APE67-dihe-in -54.67, -36.6 -52.93, -49.24 APE12-dist-in 13.297 APE11-dist-in 12.156 APE10-dist-in 6.649 APE9-dist-in 3.527 None None None XRAY 2.08 0.177 0.218 B 296 288 4 0 0 4 [[9, 275]] 1.0 6ru7 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU8A 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.425 15.156 BLAminus -131.62, -177.15 63.45, 81.35 -98.16, 25.89 286.32, 78.16 -68.14, -23.3 in-in in 7.926 Saltbr-in 2.803 HRD-in -87.78, -47.56 70.02, 4.06 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.49, 136.29 APE9-dihe-na 109.45, -154.85 APE8-dihe-in -109.19, 121.34 APE8-rot-in 302.42 APE67-dihe-in -58.68, -38.47 -55.68, -42.0 APE12-dist-in 13.563 APE11-dist-in 12.282 APE10-dist-in 6.892 APE9-dist-in 3.572 None None None XRAY 1.92 0.174 0.211 A 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU8B 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.591 15.264 BLAminus -131.67, -177.68 64.26, 82.5 -98.0, 23.89 285.39, 79.53 -66.54, -22.27 in-in in 7.662 Saltbr-in 2.78 HRD-in -88.75, -48.7 67.58, 11.08 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.47, 142.8 APE9-dihe-na 95.33, -164.73 APE8-dihe-in -102.94, 120.03 APE8-rot-in 301.71 APE67-dihe-in -59.39, -37.33 -59.11, -40.45 APE12-dist-in 12.308 APE11-dist-in 12.295 APE10-dist-in 7.245 APE9-dist-in 3.892 None None None XRAY 1.92 0.174 0.211 B 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU8C 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.558 14.983 BLAminus -128.29, -179.37 66.68, 80.46 -98.0, 22.92 288.66, 76.31 -64.33, -23.77 in-in in 7.948 Saltbr-in 2.77 HRD-in -82.99, -49.18 72.75, 4.46 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.59, 138.55 APE9-dihe-na 101.61, -152.03 APE8-dihe-in -108.82, 122.86 APE8-rot-in 298.47 APE67-dihe-in -58.74, -36.85 -58.82, -40.4 APE12-dist-in 13.04 APE11-dist-in 12.435 APE10-dist-in 6.868 APE9-dist-in 3.607 None None None XRAY 1.92 0.174 0.211 C 296 287 6 0 0 6 [[9, 275]] 1.0 6ru8 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU8D 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.534 14.975 BLAminus -126.38, -177.59 65.46, 80.95 -97.97, 21.9 288.13, 75.77 -63.86, -25.32 in-in in 7.979 Saltbr-in 2.782 HRD-in -86.34, -48.63 71.97, 3.09 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.34, 138.88 APE9-dihe-na 102.71, -155.7 APE8-dihe-in -106.76, 124.41 APE8-rot-in 298.22 APE67-dihe-in -58.88, -36.36 -58.72, -41.76 APE12-dist-in 12.717 APE11-dist-in 12.352 APE10-dist-in 6.743 APE9-dist-in 3.59 None None None XRAY 1.92 0.174 0.211 D 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7GA 8 294 415.0 AMP:303 ATPlike Inactive DFGin 6.503 15.21 BLAminus -125.58, -175.5 62.42, 84.62 -97.89, 21.28 284.93, 73.84 -62.65, -25.46 in-in in 8.252 Saltbr-in 3.016 HRD-in -80.32, -51.03 68.77, 15.13 in-in-out SNCiio in-out ActLoopNT-in 2.837 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.17, 158.18 APE9-dihe-na 70.26, -143.4 APE8-dihe-in -92.54, 123.25 APE8-rot-out 48.69 APE67-dihe-in -52.86, -40.08 -97.14, -14.35 APE12-dist-out 14.057 APE11-dist-in 12.931 APE10-dist-out 9.429 APE9-dist-out 8.015 None TPO220 TPO220 XRAY 1.7 0.173 0.208 A 296 287 0 0 0 0 [[9, 275]] 1.0 7p7g CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7P7GB 7 293 415.0 AMP:307 ATPlike Inactive DFGin 6.484 14.825 BLAminus -126.09, 178.73 70.29, 86.32 -102.39, 14.25 288.72, 93.03 -61.48, -28.95 in-in in 8.084 Saltbr-in 3.028 HRD-in -71.5, -47.28 67.0, 16.77 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -110.74, 162.01 APE9-dihe-na -98.48, -144.78 APE8-dihe-in -45.03, 124.48 APE8-rot-out 164.69 APE67-dihe-in -57.08, -42.44 -74.38, -40.7 APE12-dist-in 7.209 APE11-dist-out 6.613 APE10-dist-out 8.393 APE9-dist-in 3.884 None TPO220 TPO220 XRAY 1.7 0.173 0.208 B 296 283 2 0 0 0 [[9, 275]] 1.0 7p7g CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5IH4A 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.742 15.381 BLAminus -127.38, 171.98 74.1, 92.89 -102.61, 27.68 294.39, 95.11 -77.69, -29.22 in-out in 8.389 Saltbr-out 3.77 HRD-in -81.4, -50.53 75.25, -4.33 out-in-in SNCoii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.74, 138.15 APE9-dihe-na 95.04, -174.85 APE8-dihe-in -82.96, 136.47 APE8-rot-in 313.94 APE67-dihe-in -50.11, -38.92 -65.78, -39.41 APE12-dist-in 12.713 APE11-dist-in 11.94 APE10-dist-in 6.226 APE9-dist-in 3.836 None None None XRAY 1.9 0.193 0.227 A 294 287 6 0 0 0 [[9, 275]] 1.0 5ih4 CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXOA 2 292 415.0 No_ligand No_ligand Inactive DFGin 5.83 14.801 BLAminus -131.27, 169.62 69.74, 95.31 -105.42, 22.12 288.92, 95.11 -70.27, -22.72 in-in in 8.048 Saltbr-in 2.681 HRD-in -82.5, -47.16 68.42, 11.28 in-in-out SNCiio in-out ActLoopNT-in 2.936 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -109.35, -77.38 APE9-dihe-na -82.68, -147.73 APE8-dihe-in -72.83, 143.07 APE8-rot-out 203.92 APE67-dihe-in -63.17, -35.92 -67.57, -33.41 APE12-dist-in 11.432 APE11-dist-in 11.553 APE10-dist-in 5.961 APE9-dist-in 4.076 None None None XRAY 2.0 0.182 0.237 A 294 291 0 0 0 0 [[9, 275]] 1.0 6pxo CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXOB 1 292 415.0 No_ligand No_ligand Inactive DFGin 5.933 14.982 BLAminus -130.18, 170.18 70.22, 97.25 -104.4, 22.76 289.31, 97.78 -67.1, -25.51 in-in in 8.079 Saltbr-in 2.613 HRD-in -79.64, -46.78 70.5, 7.47 in-in-out SNCiio in-out ActLoopNT-in 2.875 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -112.52, 160.14 APE9-dihe-na -85.26, -149.51 APE8-dihe-in -68.63, 139.98 APE8-rot-out 62.2 APE67-dihe-in -64.81, -35.43 -67.5, -33.21 APE12-dist-in 7.156 APE11-dist-out 6.557 APE10-dist-out 8.475 APE9-dist-in 4.062 None None None XRAY 2.0 0.182 0.237 B 294 292 0 0 0 0 [[9, 275]] 1.0 6pxo CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7MA 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.253 15.019 BLAminus -130.46, 174.74 67.98, 83.71 -98.79, 25.27 291.86, 77.55 -66.69, -23.44 in-in in 8.095 Saltbr-in 3.072 HRD-in -82.95, -50.44 72.36, 6.41 in-in-out SNCiio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -118.7, 141.02 APE9-dihe-na 99.28, -143.16 APE8-dihe-in -115.41, 136.46 APE8-rot-out 60.38 APE67-dihe-in -67.86, -34.58 -60.29, -36.32 APE12-dist-in 12.669 APE11-dist-in 12.416 APE10-dist-in 7.086 APE9-dist-in 3.573 None None None XRAY 2.25 0.183 0.233 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7m CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7NA 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.47 14.967 BLAminus -127.99, 178.2 71.62, 81.85 -100.07, 22.57 288.0, 76.27 -69.21, -18.63 in-in in 8.123 Saltbr-in 2.877 HRD-in -86.9, -49.86 74.3, 5.74 in-in-out SNCiio in-out ActLoopNT-in 2.838 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -123.0, 132.87 APE9-dihe-na 115.13, -139.46 APE8-dihe-in -121.63, 140.17 APE8-rot-out 70.58 APE67-dihe-in -63.32, -38.4 -59.59, -40.45 APE12-dist-in 13.162 APE11-dist-in 12.499 APE10-dist-in 7.236 APE9-dist-in 3.515 None None None XRAY 1.66 0.178 0.206 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7n CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7NB 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.537 14.976 BLAminus -130.24, 179.04 70.68, 81.68 -101.75, 22.93 288.39, 79.24 -67.87, -18.61 in-in in 7.999 Saltbr-in 2.766 HRD-in -85.8, -48.58 73.18, 4.55 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.45, 133.01 APE9-dihe-na 113.72, -140.03 APE8-dihe-in -123.15, 141.08 APE8-rot-out 67.98 APE67-dihe-in -63.3, -37.53 -59.78, -40.69 APE12-dist-in 13.021 APE11-dist-in 12.267 APE10-dist-in 7.004 APE9-dist-in 3.484 None None None XRAY 1.66 0.178 0.206 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7n CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7OA 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.438 14.957 BLAminus -128.77, 177.97 69.16, 82.85 -101.02, 21.65 287.23, 75.46 -66.58, -20.22 in-in in 8.108 Saltbr-in 2.795 HRD-in -85.14, -48.58 72.65, 5.41 in-in-out SNCiio in-out ActLoopNT-in 2.796 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.6, 136.66 APE9-dihe-na 109.53, -146.1 APE8-dihe-in -119.86, 137.24 APE8-rot-out 78.45 APE67-dihe-in -65.76, -36.62 -58.64, -37.48 APE12-dist-in 13.291 APE11-dist-in 12.22 APE10-dist-in 6.881 APE9-dist-in 3.465 None None None XRAY 1.65 0.174 0.209 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7o CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8D7PA 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.246 14.911 BLAminus -133.33, 173.52 68.46, 90.57 -100.72, 25.02 287.65, 91.78 -73.72, -17.9 in-in in 7.945 Saltbr-in 2.899 HRD-in -84.4, -53.17 75.27, 6.54 in-in-out SNCiio in-out ActLoopNT-in 3.007 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -114.48, 116.2 APE9-dihe-na -153.03, -158.4 APE8-dihe-in -103.86, 112.96 APE8-rot-in 293.06 APE67-dihe-in -63.47, -32.47 -54.33, -39.64 APE12-dist-out 14.516 APE11-dist-in 10.458 APE10-dist-in 7.706 APE9-dist-in 4.683 None None None XRAY 2.25 0.199 0.251 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7p CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
9B3SA 2 415 415.0 No_ligand No_ligand Inactive DFGin 6.124 14.97 BLAminus -131.0, 174.44 67.26, 91.12 -104.02, 20.45 288.28, 101.1 -68.03, -27.02 in-out in 8.045 Saltbr-out 4.455 HRD-in -82.26, -51.13 69.79, 9.86 out-in-in SNCoii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -90.7, -46.44 APE9-dihe-na -89.21, -136.06 APE8-dihe-in -103.83, 124.46 APE8-rot-in 286.91 APE67-dihe-in -64.42, -32.2 -62.29, -32.3 APE12-dist-in 13.143 APE11-dist-in 11.532 APE10-dist-in 6.216 APE9-dist-in 3.994 None SEP411 SEP411 XRAY 2.4 0.199 0.247 A 320 300 0 0 0 0 [[9, 275]] 1.0 9b3s CK1_CSNK1D_HUMAN CK1 2.1e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
9B3SB 2 414 415.0 No_ligand No_ligand Inactive DFGin 6.205 14.552 BLAminus -130.17, 173.53 67.25, 93.15 -104.81, 23.02 293.67, 102.52 -66.31, -27.03 in-in in 7.907 Saltbr-in 2.623 HRD-in -79.37, -50.0 69.85, 7.95 in-in-out SNCiio in-out ActLoopNT-in 2.968 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -92.09, -48.23 APE9-dihe-na -89.27, -135.49 APE8-dihe-in -102.48, 124.6 APE8-rot-out 167.16 APE67-dihe-in -60.81, -30.73 -60.7, -35.64 APE12-dist-in 12.666 APE11-dist-in 11.783 APE10-dist-in 6.091 APE9-dist-in 4.096 None SEP411 SEP411 XRAY 2.4 0.199 0.247 B 320 299 0 0 0 0 [[9, 275]] 1.0 9b3s CK1_CSNK1D_HUMAN CK1 2.1e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXPB 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.336 14.439 BLAminus -135.69, 171.99 65.43, 95.83 -105.04, 23.46 292.76, 93.84 -72.82, -23.34 in-in in 8.233 Saltbr-in 3.244 HRD-in -82.3, -48.95 76.84, 1.52 in-in-out SNCiio in-out ActLoopNT-in 2.896 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -107.77, 123.24 APE9-dihe-na 110.47, 179.41 APE8-dihe-in -82.7, 140.76 APE8-rot-out 70.54 APE67-dihe-in -62.02, -36.03 -66.58, -29.77 APE12-dist-in 11.288 APE11-dist-in 11.956 APE10-dist-in 6.273 APE9-dist-in 3.65 K171E None None XRAY 2.35 0.201 0.243 B 294 293 0 0 0 0 [[9, 275]] 1.0 6pxp CK1_CSNK1D_HUMAN CK1 4.4e-122 412.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXNA 2 291 415.0 No_ligand No_ligand Inactive DFGin 5.856 14.978 BLAminus -132.46, 168.84 74.91, 102.22 -110.15, 18.1 290.1, 102.11 -68.22, -25.36 in-in in 8.187 Saltbr-in 2.754 HRD-in -80.27, -49.68 72.18, 6.82 in-in-out SNCiio in-out ActLoopNT-in 2.883 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -110.21, 152.93 APE9-dihe-na -78.09, -160.14 APE8-dihe-in -66.04, 140.6 APE8-rot-out 80.4 APE67-dihe-in -63.41, -31.35 -63.76, -40.1 APE12-dist-in 7.188 APE11-dist-out 6.662 APE10-dist-out 8.716 APE9-dist-in 3.676 R178C None None XRAY 1.551 0.178 0.205 A 415 290 0 0 0 0 [[9, 275]] 1.0 6pxn CK1_CSNK1D_HUMAN CK1 5.7e-121 408.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6PXNB 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.617 14.9 BLAminus -135.34, 169.63 75.11, 102.01 -110.62, 18.83 289.28, 101.14 -67.9, -25.06 in-in in 8.057 Saltbr-in 2.786 HRD-in -82.97, -49.17 72.12, 6.3 in-in-out SNCiio in-out ActLoopNT-in 2.891 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -119.13, 132.73 APE9-dihe-na 91.36, -172.65 APE8-dihe-in -74.3, 140.34 APE8-rot-out 74.12 APE67-dihe-in -58.52, -41.43 -65.34, -38.29 APE12-dist-in 12.05 APE11-dist-in 11.667 APE10-dist-in 6.128 APE9-dist-in 3.619 R178C None None XRAY 1.551 0.178 0.205 B 415 290 3 0 0 0 [[9, 275]] 1.0 6pxn CK1_CSNK1D_HUMAN CK1 5.7e-121 408.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8IZCA 5 294 415.0 S93:60304 Type1 Inactive DFGin 5.755 15.352 BLAminus -130.99, 169.73 72.93, 98.69 -106.38, 19.42 290.01, 102.55 -60.76, -30.82 in-out in 8.492 Saltbr-out 3.695 HRD-in -80.11, -50.45 72.82, 8.45 out-in-in SNCoii in-in ActLoopNT-in 2.89 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.08, 148.91 APE9-dihe-na 104.57, -172.82 APE8-dihe-in -90.94, 118.12 APE8-rot-in 311.15 APE67-dihe-in -52.69, -38.41 -57.32, -35.93 APE12-dist-in 11.823 APE11-dist-in 11.984 APE10-dist-in 6.4 APE9-dist-in 4.116 None None None XRAY 1.45 0.192 0.207 A 291 287 3 0 0 0 [[9, 275]] 1.0 8izc CK1_CSNK1D_HUMAN CK1 1.5e-122 414.0 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5IH5A 2 294 415.0 AUE:302 Type1 Inactive DFGin 5.915 15.467 BLAminus -135.97, 171.4 70.56, 96.84 -108.16, 25.64 287.22, 103.63 -71.2, -25.67 in-out in 8.485 Saltbr-out 3.943 HRD-in -85.95, -46.09 72.61, -4.04 out-in-in SNCoii in-in ActLoopNT-in 2.886 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.27, 140.91 APE9-dihe-na 91.08, -179.3 APE8-dihe-in -78.53, 130.37 APE8-rot-in 319.45 APE67-dihe-in -49.62, -42.09 -64.88, -37.16 APE12-dist-in 12.578 APE11-dist-in 11.639 APE10-dist-in 6.002 APE9-dist-in 3.876 None None None XRAY 2.25 0.241 0.26 A 294 287 6 0 0 0 [[9, 275]] 1.0 5ih5 CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RCGA 1 293 415.0 K0E:60303 Type1 Inactive DFGin 5.924 14.585 BLAminus -129.31, 167.16 80.86, 103.02 -107.22, 17.33 291.18, 104.04 -69.93, -23.99 in-in in 8.075 Saltbr-in 2.755 HRD-in -69.75, -46.72 69.28, 9.4 in-in-out SNCiio in-out ActLoopNT-in 2.863 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -118.81, 163.47 APE9-dihe-na -89.51, -143.43 APE8-dihe-in -74.96, 130.55 APE8-rot-out 75.54 APE67-dihe-in -56.1, -41.95 -57.15, -35.86 APE12-dist-in 7.157 APE11-dist-out 6.675 APE10-dist-out 8.321 APE9-dist-in 4.01 None None None XRAY 1.4 0.144 0.185 A 296 293 0 0 0 0 [[9, 275]] 1.0 6rcg CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QR9A 3 294 415.0 EZQ:312 Type1 Inactive DFGin 5.763 15.243 BLAminus -136.84, 176.01 69.3, 97.09 -112.84, 23.4 285.61, 104.79 -72.19, -19.25 in-out in 8.482 Saltbr-out 3.622 HRD-in -85.43, -56.75 76.41, 12.88 out-in-in SNCoii in-in ActLoopNT-in 3.124 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.41, 110.89 APE9-dihe-na 139.78, -164.56 APE8-dihe-in -98.1, 116.37 APE8-rot-in 312.63 APE67-dihe-in -59.92, -37.62 -59.14, -34.82 APE12-dist-in 12.712 APE11-dist-in 12.127 APE10-dist-in 6.731 APE9-dist-in 4.191 None None None XRAY 2.3 0.254 0.305 A 296 289 3 0 0 0 [[9, 275]] 1.0 7qr9 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QR9C 3 294 415.0 EZQ:303 Type1 Inactive DFGin 5.735 15.288 BLAminus -133.8, 175.29 70.48, 95.04 -111.33, 21.79 286.42, 101.5 -74.96, -14.27 in-out in 8.736 Saltbr-out 3.65 HRD-in -82.56, -56.81 79.28, 10.31 out-in-in SNCoii in-in ActLoopNT-in 3.13 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.84, 111.2 APE9-dihe-na 132.23, -160.89 APE8-dihe-in -99.97, 117.77 APE8-rot-in 314.9 APE67-dihe-in -61.01, -35.74 -61.99, -31.46 APE12-dist-in 11.17 APE11-dist-in 12.204 APE10-dist-in 6.441 APE9-dist-in 4.189 None None None XRAY 2.3 0.254 0.305 C 296 283 9 0 0 6 [[9, 275]] 1.0 7qr9 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7QR9D 3 294 415.0 EZQ:303 Type1 Inactive DFGin 5.714 15.342 BLAminus -134.21, 175.57 68.31, 95.27 -111.54, 22.61 286.12, 100.88 -73.82, -15.96 in-out in 8.642 Saltbr-out 3.679 HRD-in -83.63, -56.81 80.2, 8.4 out-in-in SNCoii in-in ActLoopNT-in 3.127 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.08, 111.05 APE9-dihe-na 132.46, -153.49 APE8-dihe-in -99.73, 117.4 APE8-rot-in 313.33 APE67-dihe-in -61.32, -35.02 -60.84, -33.71 APE12-dist-in 12.721 APE11-dist-in 12.262 APE10-dist-in 6.556 APE9-dist-in 4.334 None None None XRAY 2.3 0.254 0.305 D 296 283 9 0 0 6 [[9, 275]] 1.0 7qr9 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4HGTA 9 294 415.0 15G:301 Type1 Inactive DFGin 5.97 14.929 BLAminus -126.45, 174.59 58.3, 93.41 -99.95, 21.1 286.28, 98.6 -60.45, -14.72 in-in in 8.121 Saltbr-in 2.621 HRD-in -81.52, -43.64 66.43, 4.7 in-in-out SNCiio in-out ActLoopNT-in 2.82 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.93, 117.34 APE9-dihe-na 137.59, -158.78 APE8-dihe-in -111.58, 132.33 APE8-rot-out 134.04 APE67-dihe-in -51.49, -44.14 -54.45, -40.15 APE12-dist-in 13.563 APE11-dist-in 12.252 APE10-dist-in 6.704 APE9-dist-in 3.657 None None None XRAY 1.8 0.24 999.0 A 296 283 3 0 0 0 [[9, 275]] 1.0 4hgt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4HNFB 5 294 415.0 16W:301 Type1 Inactive DFGin 6.555 15.866 BLAminus -134.11, -166.41 56.81, 78.35 -103.18, 26.32 281.92, 77.82 -64.45, -33.31 in-out in 8.639 Saltbr-out 4.622 HRD-in -79.26, -38.92 65.6, -2.59 out-in-in SNCoii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.72, 118.09 APE9-dihe-na 133.0, -140.96 APE8-dihe-in -114.37, 128.18 APE8-rot-in 299.03 APE67-dihe-in -47.74, -37.42 -57.39, -49.8 APE12-dist-in 12.605 APE11-dist-in 11.819 APE10-dist-in 6.019 APE9-dist-in 4.711 None None None XRAY 2.07 0.241 0.274 B 296 290 0 0 0 0 [[9, 275]] 1.0 4hnf CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8VXDA 1 292 415.0 A1AD7:301 Type1 Inactive DFGin 6.825 15.091 BLAminus -131.19, -178.07 60.49, 73.82 -94.08, 18.87 291.45, 100.43 -70.24, -19.54 in-out in 8.178 Saltbr-out 4.036 HRD-in -79.2, -51.15 72.31, 8.44 out-in-out SNCoio in-out ActLoopNT-in 2.756 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -87.26, 134.18 APE9-dihe-na 97.04, -154.76 APE8-dihe-in -102.88, 131.3 APE8-rot-out 183.48 APE67-dihe-in -57.18, -40.09 -63.12, -35.04 APE12-dist-in 12.251 APE11-dist-in 12.074 APE10-dist-in 6.302 APE9-dist-in 4.009 None None None XRAY 2.47 0.267 0.295 A 300 285 7 0 0 0 [[9, 275]] 1.0 8vxd CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
8VXDB 2 298 415.0 A1AD7:301 Type1 Inactive DFGin 6.034 14.743 BLAminus -131.39, -173.06 64.42, 76.08 -97.65, 19.56 289.92, 99.45 -69.34, -18.73 in-in in 8.266 Saltbr-in 2.794 HRD-in -78.49, -50.68 72.77, 8.1 in-in-out SNCiio in-out ActLoopNT-in 2.752 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnii APE10-dihe-na 999.0, -41.14 APE9-dihe-na -68.33, -154.01 APE8-dihe-in -101.8, 131.54 APE8-rot-out 206.9 APE67-dihe-in -58.04, -40.67 -62.8, -36.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 6.43 APE9-dist-in 4.032 None None None XRAY 2.47 0.267 0.295 B 300 291 6 0 0 4 [[9, 275]] 1.0 8vxd CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVA 8 293 415.0 D5Q:301 Type1 Inactive DFGin 5.83 15.023 BLAminus -131.68, 168.75 74.06, 95.12 -107.7, 21.28 292.0, 96.98 -64.87, -25.36 in-in in 8.301 Saltbr-in 2.849 HRD-in -82.15, -48.81 72.48, 10.52 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.17, 102.31 APE9-dihe-na 125.3, -162.28 APE8-dihe-in -82.86, 141.1 APE8-rot-out 194.99 APE67-dihe-in -59.47, -41.03 -72.7, -36.43 APE12-dist-in 11.803 APE11-dist-in 11.631 APE10-dist-in 5.956 APE9-dist-in 4.126 None None None XRAY 2.154 0.173 0.192 A 314 286 0 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVC 6 293 415.0 D5Q:301 Type1 Inactive DFGin 5.714 14.884 BLAminus -131.22, 168.19 73.22, 96.74 -107.26, 21.85 293.35, 97.6 -65.13, -25.75 in-in in 8.298 Saltbr-in 2.772 HRD-in -81.63, -48.95 72.04, 11.04 in-in-out SNCiio in-out ActLoopNT-in 2.871 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -115.55, 80.17 APE9-dihe-na 157.75, -163.71 APE8-dihe-in -83.2, 139.38 APE8-rot-out 188.1 APE67-dihe-in -59.64, -40.6 -72.53, -35.85 APE12-dist-in 12.044 APE11-dist-in 11.693 APE10-dist-in 6.111 APE9-dist-in 4.185 None None None XRAY 2.154 0.173 0.192 C 314 288 0 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5MQVF 7 294 415.0 D5Q:301 Type1 Inactive DFGin 5.854 14.974 BLAminus -131.24, 169.41 73.24, 95.61 -107.61, 22.25 292.68, 97.01 -65.28, -25.58 in-in in 8.285 Saltbr-in 2.786 HRD-in -81.61, -48.18 72.2, 10.47 in-in-out SNCiio in-out ActLoopNT-in 2.924 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.6, 122.3 APE9-dihe-na 113.02, -165.98 APE8-dihe-in -85.3, 139.57 APE8-rot-out 192.65 APE67-dihe-in -59.21, -40.66 -71.37, -34.49 APE12-dist-in 12.193 APE11-dist-in 11.77 APE10-dist-in 6.163 APE9-dist-in 3.821 None None None XRAY 2.154 0.173 0.192 F 314 286 2 0 0 0 [[9, 275]] 1.0 5mqv CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6GZMA 5 295 415.0 LCI:1004 Type1 Inactive DFGin 6.092 14.898 BLAminus -124.32, 164.33 79.67, 96.2 -103.0, 21.73 291.46, 97.37 -70.61, -17.22 in-in in 7.992 Saltbr-in 3.067 HRD-in -80.76, -48.3 70.22, 11.09 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -102.57, -30.36 APE9-dihe-na -78.6, -147.37 APE8-dihe-in -125.32, 169.57 APE8-rot-out 191.56 APE67-dihe-in -53.28, -42.94 -88.52, -29.67 APE12-dist-in 13.557 APE11-dist-in 12.32 APE10-dist-in 6.969 APE9-dist-in 4.557 R13N None None XRAY 1.59 0.192 0.25 A 295 291 0 0 0 0 [[9, 275]] 1.0 6gzm CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBKD 3 293 415.0 1QG:401 Type1 Inactive DFGin 5.881 14.926 BLAminus -131.43, 175.27 63.3, 98.83 -106.81, 21.53 289.62, 102.69 -62.31, -31.85 in-in in 8.355 Saltbr-in 2.919 HRD-in -74.75, -48.67 75.76, -0.04 in-in-out SNCiio in-out ActLoopNT-in 2.915 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -103.02, 130.08 APE9-dihe-na 105.3, -173.89 APE8-dihe-in -83.33, 130.0 APE8-rot-out 40.11 APE67-dihe-in -55.34, -39.95 -56.81, -38.76 APE12-dist-in 12.407 APE11-dist-in 12.083 APE10-dist-in 6.378 APE9-dist-in 3.679 None None None XRAY 2.1 0.193 0.225 D 331 281 10 0 0 0 [[9, 275]] 1.0 4kbk CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
6RU6B 3 294 415.0 ACP:60301 ATPlike None DFGin 6.59 15.156 BLAminus -129.63, 177.25 73.9, 71.28 -92.31, 21.27 283.76, 74.29 -58.84, -31.38 in-in in 7.818 Saltbr-in 2.796 HRD-in -76.32, -55.32 74.02, 14.82 in-in-none SNCiin in-none ActLoopNT-in 2.86 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.17 APE8-dihe-in -104.51, 127.76 APE8-rot-in 311.88 APE67-dihe-in -57.59, -35.09 -58.93, -44.33 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.941 None None None XRAY 2.05 0.213 0.257 B 296 278 14 0 0 8 [[9, 275]] 1.0 6ru6 CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
3UYTD 4 294 415.0 0CK:295 Type1 None DFGin 6.058 14.902 BLAminus -125.11, 171.89 69.6, 107.56 -115.59, 22.0 279.81, 112.96 -71.13, -36.34 in-in in 8.444 Saltbr-in 3.03 HRD-in -87.06, -44.31 72.64, -9.74 in-in-none SNCiin in-none ActLoopNT-in 2.996 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, 157.15 APE9-dihe-na 110.54, 179.72 APE8-dihe-in -77.04, 125.8 APE8-rot-in 336.84 APE67-dihe-in -54.65, -24.61 -55.67, -34.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 6.132 APE9-dist-in 4.59 None None None XRAY 2.0 0.244 0.264 D 296 268 23 0 0 16 [[9, 275]] 1.0 3uyt CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
5OKTB 4 294 415.0 9XK:301 Type1 None DFGin 6.127 14.635 BLAminus -133.48, 170.79 70.83, 88.65 -98.93, 18.4 294.6, 95.75 -62.62, -31.39 in-in in 7.966 Saltbr-in 2.832 HRD-in -78.04, -48.78 74.52, -0.37 in-in-none SNCiin in-none ActLoopNT-in 2.878 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -70.45 APE9-dihe-na -87.34, -162.07 APE8-dihe-in -74.91, 135.72 APE8-rot-in 311.98 APE67-dihe-in -57.97, -40.98 -67.96, -35.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.351 APE9-dist-in 3.835 None TPO220 TPO220 XRAY 2.13 0.194 0.221 B 314 282 9 0 0 9 [[9, 275]] 1.0 5okt CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
7NZYB 2 294 415.0 UX2:301 Type1 None DFGin 6.558 14.882 BLAminus -133.2, 168.2 69.93, 96.11 -104.78, 25.32 292.5, 81.62 -64.88, -24.78 in-in in 8.136 Saltbr-in 2.965 HRD-in -79.22, -50.76 76.11, 7.31 in-in-none SNCiin in-none ActLoopNT-in 2.89 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -70.52, -73.6 APE9-dihe-na -68.02, -150.38 APE8-dihe-in -91.32, 139.07 APE8-rot-in 311.34 APE67-dihe-in -57.14, -39.91 -68.37, -36.29 APE12-dist-none 999.0 APE11-dist-in 11.813 APE10-dist-in 6.872 APE9-dist-in 3.731 None TPO220 TPO220 XRAY 1.85 0.205 0.229 B 314 286 7 0 0 7 [[9, 275]] 1.0 7nzy CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KB8A 3 293 415.0 1QN:401 Type1 None DFGin 5.98 14.795 BLAminus -126.76, 172.83 67.65, 98.79 -108.65, 18.05 291.14, 100.67 -60.78, -33.86 in-in in 8.264 Saltbr-in 2.885 HRD-in -74.47, -48.24 76.4, -6.59 in-in-none SNCiin in-none ActLoopNT-in 2.926 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -159.46 APE8-dihe-in -103.07, 128.56 APE8-rot-in 304.05 APE67-dihe-in -56.21, -39.45 -54.48, -41.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.597 None None None XRAY 1.95 0.207 0.232 A 331 265 26 0 0 18 [[9, 275]] 1.0 4kb8 CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
4KBAA 3 293 415.0 1QM:401 Type1 None DFGin 5.942 14.713 BLAminus -128.03, 172.49 65.02, 105.13 -114.85, 19.06 291.3, 105.5 -62.25, -33.76 in-in in 8.12 Saltbr-in 2.814 HRD-in -73.17, -51.42 78.43, -6.31 in-in-none SNCiin in-none ActLoopNT-in 2.918 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -160.81 APE8-dihe-in -100.61, 126.43 APE8-rot-in 305.06 APE67-dihe-in -59.74, -39.86 -55.88, -36.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.561 None None None XRAY 1.98 0.21 0.237 A 331 263 28 0 0 18 [[9, 275]] 1.0 4kba CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta

CK1_CSNK1D (Casein kinase I isoform delta)

Total number of chains: 128
Active chains: 89
Family: CK1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 128 100.0% AF-P48730-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KC1D_HUMAN 6RU6A P48730 3 294 415.0 ACP:60301 ATPlike Active DFGin 6.436 15.264 BLAminus -136.56, 176.84 69.53, 73.53 -93.66, 24.95 289.84, 81.36 -61.77, -30.96 in-in in 7.923 Saltbr-in 2.789 HRD-in -77.83, -55.12 76.08, 12.52 in-in-in SNCiii in-in ActLoopNT-in 2.85 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.64, 119.59 APE9-dihe-na 102.6, -136.74 APE8-dihe-in -117.46, 127.27 APE8-rot-in 311.09 APE67-dihe-in -57.82, -37.85 -53.66, -47.41 APE12-dist-in 12.315 APE11-dist-in 11.908 APE10-dist-in 6.481 APE9-dist-in 3.505 None None None XRAY 2.05 0.213 0.257 A 296 288 4 0 0 0 [[9, 275]] 1.0 6ru6 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7FA P48730 3 294 415.0 AMP:305 ATPlike Active DFGin 6.386 14.989 BLAminus -135.41, 179.24 65.29, 82.6 -99.51, 20.86 287.48, 77.77 -56.63, -36.85 in-in in 8.099 Saltbr-in 2.591 HRD-in -82.17, -51.93 74.76, 11.47 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.01, 118.96 APE9-dihe-na 109.81, -163.5 APE8-dihe-in -91.97, 119.49 APE8-rot-in 320.94 APE67-dihe-in -55.9, -38.32 -51.55, -37.41 APE12-dist-in 13.114 APE11-dist-in 12.585 APE10-dist-in 6.845 APE9-dist-in 3.948 None TPO220 TPO220 XRAY 1.96 0.19 0.221 A 296 292 0 0 0 0 [[9, 275]] 1.0 7p7f Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7FB P48730 3 294 415.0 AMP:310 ATPlike Active DFGin 6.389 15.041 BLAminus -134.9, -178.65 62.6, 84.78 -99.93, 21.19 288.23, 78.97 -57.89, -34.16 in-in in 8.117 Saltbr-in 2.593 HRD-in -86.23, -54.05 76.65, 11.34 in-in-in SNCiii in-in ActLoopNT-in 2.909 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.84, 118.88 APE9-dihe-na 108.83, -162.51 APE8-dihe-in -93.95, 118.29 APE8-rot-in 320.41 APE67-dihe-in -55.93, -38.53 -50.49, -37.42 APE12-dist-in 13.14 APE11-dist-in 12.546 APE10-dist-in 6.804 APE9-dist-in 4.014 None TPO220 TPO220 XRAY 1.96 0.19 0.221 B 296 292 0 0 0 0 [[9, 275]] 1.0 7p7f Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7HA P48730 3 294 415.0 AMP:301 ATPlike Active DFGin 5.85 14.904 BLAminus -131.69, 175.32 69.71, 86.46 -98.17, 29.2 291.07, 84.43 -61.3, -36.51 in-in in 8.328 Saltbr-in 2.869 HRD-in -85.02, -56.99 74.97, 14.35 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.26, -19.24 APE9-dihe-na -88.34, -159.24 APE8-dihe-in -92.63, 127.36 APE8-rot-in 313.8 APE67-dihe-in -57.88, -32.21 -74.29, -29.96 APE12-dist-in 10.816 APE11-dist-in 12.399 APE10-dist-in 6.988 APE9-dist-in 4.101 None None None XRAY 2.4 0.225 0.268 A 296 292 0 0 0 0 [[9, 275]] 1.0 7p7h Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7HB P48730 3 294 415.0 AMP:301 ATPlike Active DFGin 5.843 14.916 BLAminus -130.5, 174.9 69.57, 86.72 -100.58, 28.91 292.34, 82.14 -57.01, -35.01 in-in in 8.325 Saltbr-in 2.918 HRD-in -84.55, -57.9 81.6, 9.08 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.93, 49.41 APE9-dihe-na 140.08, -131.01 APE8-dihe-in -99.84, 119.2 APE8-rot-in 321.52 APE67-dihe-in -56.55, -33.9 -75.78, -27.7 APE12-dist-in 12.421 APE11-dist-in 12.165 APE10-dist-in 7.215 APE9-dist-in 4.736 None None None XRAY 2.4 0.225 0.268 B 296 292 0 0 0 0 [[9, 275]] 1.0 7p7h Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN AF-P48730-K1A P48730 1 283 415.0 No_ligand No_ligand Active DFGin 6.014 14.738 BLAminus -133.52, 176.85 64.1, 66.27 -77.63, 11.73 293.67, 97.86 -60.56, -26.09 in-in in 8.117 Saltbr-in 2.685 HRD-in -76.86, -43.78 66.27, -7.2 in-in-in SNCiii in-in ActLoopNT-in 2.829 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.58, 134.54 APE9-dihe-na 97.48, -176.89 APE8-dihe-in -80.26, 109.12 APE8-rot-in 301.44 APE67-dihe-in -58.05, -41.24 -50.16, -30.35 APE12-dist-in 12.286 APE11-dist-in 12.4 APE10-dist-in 6.762 APE9-dist-in 3.559 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[9, 275]] 1.0 AF-P48730-K1 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.3e-122 414.1 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN AF-P48730-K3A P48730 1 283 415.0 No_ligand No_ligand Active DFGin 6.036 14.99 BLAminus -135.79, -179.69 65.66, 57.84 -74.43, 9.28 295.07, 110.08 -61.57, -21.47 in-in in 8.244 Saltbr-in 2.688 HRD-in -75.16, -44.32 68.95, -5.99 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.24, 137.17 APE9-dihe-na 87.75, -172.14 APE8-dihe-in -81.8, 106.79 APE8-rot-in 298.65 APE67-dihe-in -57.57, -40.66 -46.21, -33.58 APE12-dist-in 12.33 APE11-dist-in 12.46 APE10-dist-in 6.972 APE9-dist-in 3.344 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[9, 275]] 1.0 AF-P48730-K3 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.3e-122 414.1 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RCHB P48730 1 293 415.0 No_ligand No_ligand Active DFGin 5.843 14.557 BLAminus -131.65, 170.96 76.64, 96.11 -104.66, 20.03 292.76, 102.3 -66.03, -25.81 in-in in 7.929 Saltbr-in 2.638 HRD-in -82.16, -49.05 70.48, 10.61 in-in-in SNCiii in-in ActLoopNT-in 2.87 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -103.36, -16.93 APE9-dihe-na -91.24, -146.45 APE8-dihe-in -101.75, 113.83 APE8-rot-in 306.19 APE67-dihe-in -56.37, -33.25 -58.53, -38.11 APE12-dist-in 12.316 APE11-dist-in 12.015 APE10-dist-in 7.0 APE9-dist-in 4.335 None None None XRAY 1.45 0.157 0.178 B 296 293 0 0 0 0 [[9, 275]] 1.0 6rch Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYSA P48730 4 294 415.0 No_ligand No_ligand Active DFGin 6.102 15.072 BLAminus -135.99, -172.72 54.24, 84.3 -98.01, 23.68 285.73, 116.84 -62.69, -28.36 in-in in 8.356 Saltbr-in 2.611 HRD-in -83.32, -46.5 68.28, 7.86 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.95, 102.73 APE9-dihe-na 151.96, -149.32 APE8-dihe-in -118.11, 114.68 APE8-rot-in 297.33 APE67-dihe-in -67.47, -40.27 -52.12, -24.47 APE12-dist-in 13.143 APE11-dist-in 12.267 APE10-dist-in 6.813 APE9-dist-in 4.11 None None None XRAY 2.3 0.238 0.276 A 296 281 10 0 0 0 [[9, 275]] 1.0 3uys Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYSB P48730 4 294 415.0 No_ligand No_ligand Active DFGin 6.122 15.305 BLAminus -123.48, -176.29 49.64, 104.5 -109.98, 26.53 290.32, 65.97 -66.14, -7.64 in-in in 8.686 Saltbr-in 2.902 HRD-in -63.12, -39.01 58.16, 15.19 in-in-in SNCiii in-in ActLoopNT-in 3.005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.51, 106.93 APE9-dihe-na 146.4, -128.36 APE8-dihe-in -129.25, 128.0 APE8-rot-in 311.95 APE67-dihe-in -54.57, -43.47 -56.45, -39.42 APE12-dist-in 12.939 APE11-dist-in 11.871 APE10-dist-in 6.445 APE9-dist-in 4.15 None None None XRAY 2.3 0.238 0.276 B 296 279 12 0 0 0 [[9, 275]] 1.0 3uys Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYSC P48730 4 294 415.0 No_ligand No_ligand Active DFGin 6.17 14.989 BLAminus -134.31, -179.28 58.1, 91.57 -102.86, 27.33 288.56, 103.71 -68.45, -23.02 in-in in 8.167 Saltbr-in 3.006 HRD-in -74.66, -53.28 79.91, 5.21 in-in-in SNCiii in-in ActLoopNT-in 3.101 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.65, 112.01 APE9-dihe-na 135.42, -174.74 APE8-dihe-in -92.63, 117.69 APE8-rot-in 318.84 APE67-dihe-in -76.69, -30.13 -57.91, -14.76 APE12-dist-in 12.529 APE11-dist-in 12.063 APE10-dist-in 6.4 APE9-dist-in 3.903 None None None XRAY 2.3 0.238 0.276 C 296 286 5 0 0 4 [[9, 275]] 1.0 3uys Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYSD P48730 4 294 415.0 No_ligand No_ligand Active DFGin 5.978 14.973 BLAminus -135.58, 176.18 66.3, 85.15 -100.12, 27.44 287.44, 108.47 -71.4, -34.89 in-in in 8.26 Saltbr-in 2.909 HRD-in -74.17, -45.77 69.63, -6.25 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.44, 116.33 APE9-dihe-na 132.39, -162.25 APE8-dihe-in -97.61, 129.12 APE8-rot-in 319.85 APE67-dihe-in -65.73, -32.75 -68.54, -21.24 APE12-dist-in 12.774 APE11-dist-in 12.098 APE10-dist-in 6.503 APE9-dist-in 4.271 None None None XRAY 2.3 0.238 0.276 D 296 284 7 0 0 0 [[9, 275]] 1.0 3uys Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7MB P48730 2 290 415.0 No_ligand No_ligand Active DFGin 6.366 15.054 BLAminus -133.02, 176.99 67.05, 83.52 -99.86, 23.87 288.55, 76.27 -66.65, -21.08 in-in in 7.994 Saltbr-in 2.747 HRD-in -83.86, -50.81 73.21, 7.48 in-in-in SNCiii in-in ActLoopNT-in 2.918 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.04, 138.78 APE9-dihe-na 100.9, -144.49 APE8-dihe-in -113.42, 133.79 APE8-rot-in 286.18 APE67-dihe-in -68.47, -33.95 -60.62, -36.47 APE12-dist-in 12.874 APE11-dist-in 12.443 APE10-dist-in 7.065 APE9-dist-in 3.614 None None None XRAY 2.25 0.183 0.233 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7m Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7OB P48730 2 290 415.0 No_ligand No_ligand Active DFGin 6.707 14.954 BLAminus -129.86, -179.93 67.27, 80.46 -100.25, 21.82 286.61, 77.74 -67.58, -21.13 in-in in 8.052 Saltbr-in 2.827 HRD-in -85.94, -49.67 73.0, 5.76 in-in-in SNCiii in-in ActLoopNT-in 2.848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.84, 136.91 APE9-dihe-na 109.35, -145.96 APE8-dihe-in -119.11, 136.0 APE8-rot-in 295.77 APE67-dihe-in -64.5, -36.47 -59.05, -40.84 APE12-dist-in 13.253 APE11-dist-in 12.2 APE10-dist-in 6.908 APE9-dist-in 3.455 None None None XRAY 1.65 0.174 0.209 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7o Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7PB P48730 2 290 415.0 No_ligand No_ligand Active DFGin 5.859 14.67 BLAminus -130.49, 172.66 68.65, 91.76 -101.03, 25.87 297.23, 90.22 -72.86, -19.19 in-in in 8.015 Saltbr-in 2.456 HRD-in -85.55, -52.52 74.69, 6.14 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.07, 117.73 APE9-dihe-na -149.93, -159.97 APE8-dihe-in -104.9, 114.63 APE8-rot-in 293.84 APE67-dihe-in -64.02, -31.31 -56.89, -40.01 APE12-dist-in 13.303 APE11-dist-in 10.243 APE10-dist-in 7.565 APE9-dist-in 4.675 None None None XRAY 2.25 0.199 0.251 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7p Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TN6B P48730 2 292 415.0 No_ligand No_ligand Active DFGin 6.047 14.793 BLAminus -131.93, 175.74 67.68, 89.2 -98.57, 20.63 293.04, 101.16 -63.36, -31.28 in-in in 8.009 Saltbr-in 2.892 HRD-in -77.62, -48.19 67.28, 6.53 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.84, 98.76 APE9-dihe-na 123.78, -164.81 APE8-dihe-in -90.48, 131.01 APE8-rot-in 310.94 APE67-dihe-in -53.03, -41.99 -58.19, -43.36 APE12-dist-in 11.393 APE11-dist-in 11.652 APE10-dist-in 6.054 APE9-dist-in 3.92 None None None XRAY 2.41 0.19 0.239 B 318 285 3 0 0 0 [[9, 275]] 1.0 4tn6 Homo sapiens CK1_CSNK1D_HUMAN CK1 2e-122 413.5 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXPA P48730 2 293 415.0 No_ligand No_ligand Active DFGin 5.983 14.851 BLAminus -137.52, 172.85 65.52, 95.22 -107.76, 25.56 291.17, 109.72 -73.49, -24.5 in-in in 8.254 Saltbr-in 2.912 HRD-in -81.44, -47.41 77.01, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.964 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.57, 122.69 APE9-dihe-na 111.56, 179.84 APE8-dihe-in -78.24, 136.92 APE8-rot-in 308.99 APE67-dihe-in -60.53, -35.81 -68.97, -29.32 APE12-dist-in 10.48 APE11-dist-in 11.788 APE10-dist-in 6.065 APE9-dist-in 3.705 K171E None None XRAY 2.35 0.201 0.243 A 294 288 4 0 0 0 [[9, 275]] 1.0 6pxp Homo sapiens CK1_CSNK1D_HUMAN CK1 4.4e-122 412.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8IZCB P48730 5 294 415.0 S93:60303 Type1 Active DFGin 5.795 15.13 BLAminus -127.75, 168.53 74.17, 99.03 -107.93, 19.19 290.65, 101.85 -62.94, -27.99 in-in in 8.485 Saltbr-in 3.369 HRD-in -80.22, -50.17 74.11, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -104.14, 152.75 APE9-dihe-na 103.35, -169.22 APE8-dihe-in -99.98, 119.89 APE8-rot-in 309.34 APE67-dihe-in -53.04, -39.2 -57.61, -35.96 APE12-dist-in 11.953 APE11-dist-in 12.011 APE10-dist-in 6.408 APE9-dist-in 3.978 None None None XRAY 1.45 0.192 0.207 B 291 290 0 0 0 0 [[9, 275]] 1.0 8izc Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 414.0 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5IH6A P48730 2 293 415.0 AUG:305 Type1 Active DFGin 5.9 15.482 BLAminus -128.7, 171.19 73.47, 91.55 -103.56, 28.82 292.29, 98.11 -73.23, -29.86 in-in in 8.572 Saltbr-in 3.419 HRD-in -87.62, -49.57 76.35, -3.83 in-in-in SNCiii in-in ActLoopNT-in 3.002 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.33, 137.88 APE9-dihe-na 98.97, -178.76 APE8-dihe-in -78.42, 134.27 APE8-rot-in 320.15 APE67-dihe-in -51.8, -40.15 -63.26, -37.67 APE12-dist-in 12.526 APE11-dist-in 11.843 APE10-dist-in 6.114 APE9-dist-in 3.84 None None None XRAY 2.3 0.234 0.26 A 294 286 6 0 0 0 [[9, 275]] 1.0 5ih6 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7FC P48730 4 294 415.0 ADN:307 Type1 Active DFGin 6.287 14.774 BLAminus -127.27, 170.02 72.27, 90.59 -100.52, 22.08 289.81, 85.32 -63.29, -31.3 in-in in 7.933 Saltbr-in 2.63 HRD-in -80.78, -51.31 76.2, 11.32 in-in-in SNCiii in-in ActLoopNT-in 2.918 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.83, -40.42 APE9-dihe-na -88.08, -154.15 APE8-dihe-in -92.07, 119.61 APE8-rot-in 316.8 APE67-dihe-in -56.43, -36.06 -56.0, -37.52 APE12-dist-in 12.693 APE11-dist-in 12.117 APE10-dist-in 6.391 APE9-dist-in 4.324 None TPO220 TPO220 XRAY 1.96 0.19 0.221 C 296 285 6 0 0 6 [[9, 275]] 1.0 7p7f Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7FD P48730 4 294 415.0 ADN:309 Type1 Active DFGin 6.224 14.767 BLAminus -126.64, 169.11 73.89, 91.36 -99.69, 21.56 289.8, 84.96 -66.02, -29.96 in-in in 7.952 Saltbr-in 2.667 HRD-in -81.57, -51.69 78.22, 8.75 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.24, -37.1 APE9-dihe-na -85.95, -158.82 APE8-dihe-in -90.13, 119.34 APE8-rot-in 319.47 APE67-dihe-in -54.92, -36.79 -58.02, -35.64 APE12-dist-in 13.37 APE11-dist-in 12.222 APE10-dist-in 6.519 APE9-dist-in 4.362 None TPO220 TPO220 XRAY 1.96 0.19 0.221 D 296 285 6 0 0 6 [[9, 275]] 1.0 7p7f Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QR9B P48730 2 294 415.0 EZQ:304 Type1 Active DFGin 5.736 15.259 BLAminus -137.93, 175.93 70.34, 95.42 -112.76, 22.31 285.98, 104.42 -71.79, -20.33 in-in in 8.494 Saltbr-in 3.033 HRD-in -85.88, -57.56 74.9, 13.35 in-in-in SNCiii in-in ActLoopNT-in 3.121 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.3, 111.05 APE9-dihe-na 138.52, -161.09 APE8-dihe-in -99.08, 116.92 APE8-rot-in 313.8 APE67-dihe-in -61.25, -36.96 -59.19, -34.06 APE12-dist-in 12.385 APE11-dist-in 12.095 APE10-dist-in 6.629 APE9-dist-in 4.19 None None None XRAY 2.3 0.254 0.305 B 296 291 2 0 0 0 [[9, 275]] 1.0 7qr9 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRAA P48730 3 294 415.0 EYI:307 Type1 Active DFGin 5.739 15.212 BLAminus -129.63, 174.95 73.0, 97.71 -116.41, 24.77 288.45, 102.87 -71.56, -22.75 in-in in 8.527 Saltbr-in 2.784 HRD-in -85.23, -60.7 76.19, 18.85 in-in-in SNCiii in-in ActLoopNT-in 2.973 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -82.29, -40.65 APE9-dihe-na -87.45, -140.73 APE8-dihe-in -96.68, 126.6 APE8-rot-in 315.63 APE67-dihe-in -60.1, -39.91 -69.45, -28.12 APE12-dist-in 12.097 APE11-dist-in 12.053 APE10-dist-in 6.433 APE9-dist-in 3.891 None None None XRAY 2.4 0.241 0.282 A 296 289 3 0 0 0 [[9, 275]] 1.0 7qra Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRAB P48730 3 294 415.0 EYI:308 Type1 Active DFGin 5.764 15.183 BLAminus -130.87, 174.1 72.72, 98.11 -115.7, 24.4 288.11, 100.43 -70.38, -23.64 in-in in 8.561 Saltbr-in 2.768 HRD-in -84.79, -60.13 77.89, 15.35 in-in-in SNCiii in-in ActLoopNT-in 2.965 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.51, -41.22 APE9-dihe-na -87.16, -142.78 APE8-dihe-in -95.48, 126.32 APE8-rot-in 317.4 APE67-dihe-in -62.31, -40.0 -66.85, -28.92 APE12-dist-in 12.377 APE11-dist-in 12.072 APE10-dist-in 6.452 APE9-dist-in 3.944 None None None XRAY 2.4 0.241 0.282 B 296 289 3 0 0 0 [[9, 275]] 1.0 7qra Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRAC P48730 3 294 415.0 EYI:305 Type1 Active DFGin 5.844 15.171 BLAminus -126.88, 173.42 75.27, 97.85 -115.56, 23.0 289.2, 100.23 -73.01, -21.24 in-in in 8.536 Saltbr-in 2.851 HRD-in -84.69, -59.53 80.0, 13.31 in-in-in SNCiii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.55, 110.63 APE9-dihe-na 137.63, -156.44 APE8-dihe-in -96.52, 125.23 APE8-rot-in 317.11 APE67-dihe-in -61.28, -38.81 -74.42, -24.35 APE12-dist-in 13.448 APE11-dist-in 12.036 APE10-dist-in 6.428 APE9-dist-in 4.257 None None None XRAY 2.4 0.241 0.282 C 296 280 12 0 0 9 [[9, 275]] 1.0 7qra Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRAD P48730 3 294 415.0 EYI:304 Type1 Active DFGin 5.888 15.199 BLAminus -125.88, 173.32 76.1, 97.96 -116.31, 23.64 289.96, 100.23 -73.22, -20.1 in-in in 8.622 Saltbr-in 2.839 HRD-in -83.39, -59.49 80.05, 13.06 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.71, 111.44 APE9-dihe-na 139.23, -155.32 APE8-dihe-in -97.46, 125.75 APE8-rot-in 316.99 APE67-dihe-in -61.28, -37.47 -73.02, -28.07 APE12-dist-in 13.411 APE11-dist-in 11.996 APE10-dist-in 6.435 APE9-dist-in 4.231 None None None XRAY 2.4 0.241 0.282 D 296 280 12 0 0 9 [[9, 275]] 1.0 7qra Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRBA P48730 3 294 415.0 EX9:303 Type1 Active DFGin 5.786 14.749 BLAminus -138.57, 173.71 74.23, 97.05 -111.52, 23.54 292.13, 96.9 -64.17, -33.44 in-in in 8.054 Saltbr-in 3.32 HRD-in -80.6, -62.98 85.02, 10.42 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.53, -38.97 APE9-dihe-na -79.34, -143.1 APE8-dihe-in -104.26, 120.14 APE8-rot-in 303.67 APE67-dihe-in -58.5, -38.92 -56.29, -38.68 APE12-dist-in 11.569 APE11-dist-in 12.023 APE10-dist-in 6.479 APE9-dist-in 3.619 None None None XRAY 2.6 0.231 0.273 A 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRBB P48730 3 294 415.0 EX9:304 Type1 Active DFGin 5.864 14.858 BLAminus -136.87, 171.91 74.6, 98.93 -112.49, 24.79 293.01, 96.72 -66.73, -32.74 in-in in 8.061 Saltbr-in 3.313 HRD-in -79.65, -62.36 86.77, 5.68 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.7, -39.26 APE9-dihe-na -82.5, -142.47 APE8-dihe-in -103.22, 119.83 APE8-rot-in 303.38 APE67-dihe-in -57.15, -38.6 -56.04, -38.93 APE12-dist-in 11.587 APE11-dist-in 11.936 APE10-dist-in 6.251 APE9-dist-in 3.66 None None None XRAY 2.6 0.231 0.273 B 296 286 6 0 0 6 [[9, 275]] 1.0 7qrb Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRBC P48730 3 294 415.0 EX9:304 Type1 Active DFGin 5.83 14.833 BLAminus -136.6, 172.53 75.75, 98.41 -112.93, 24.4 292.54, 96.74 -63.85, -34.66 in-in in 8.075 Saltbr-in 3.337 HRD-in -77.66, -63.11 86.68, 6.65 in-in-in SNCiii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.13, -39.43 APE9-dihe-na -82.01, -141.99 APE8-dihe-in -104.01, 120.43 APE8-rot-in 304.37 APE67-dihe-in -57.15, -38.63 -55.0, -40.36 APE12-dist-in 11.611 APE11-dist-in 11.922 APE10-dist-in 6.301 APE9-dist-in 3.646 None None None XRAY 2.6 0.231 0.273 C 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QRBD P48730 3 294 415.0 EX9:304 Type1 Active DFGin 5.848 14.758 BLAminus -138.94, 173.09 73.42, 97.56 -112.5, 24.45 292.46, 98.28 -63.82, -34.18 in-in in 8.054 Saltbr-in 3.317 HRD-in -78.8, -62.72 85.13, 9.67 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.2, -41.31 APE9-dihe-na -85.0, -140.82 APE8-dihe-in -103.74, 120.37 APE8-rot-in 302.04 APE67-dihe-in -59.1, -39.29 -54.22, -40.17 APE12-dist-in 11.758 APE11-dist-in 12.03 APE10-dist-in 6.411 APE9-dist-in 3.551 None None None XRAY 2.6 0.231 0.273 D 296 292 0 0 0 0 [[9, 275]] 1.0 7qrb Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYTA P48730 5 294 415.0 0CK:295 Type1 Active DFGin 5.914 14.938 BLAminus -141.08, 175.99 67.87, 107.54 -117.55, 28.27 290.71, 107.29 -70.97, -30.55 in-in in 8.507 Saltbr-in 2.578 HRD-in -69.52, -53.91 74.76, 11.3 in-in-in SNCiii in-in ActLoopNT-in 2.99 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.54, 92.6 APE9-dihe-na 157.25, -156.27 APE8-dihe-in -105.18, 125.66 APE8-rot-in 309.98 APE67-dihe-in -52.24, -36.38 -55.43, -45.0 APE12-dist-in 12.286 APE11-dist-in 11.403 APE10-dist-in 5.737 APE9-dist-in 3.605 None None None XRAY 2.0 0.244 0.264 A 296 287 3 0 0 0 [[9, 275]] 1.0 3uyt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYTB P48730 5 293 415.0 0CK:295 Type1 Active DFGin 5.42 14.466 BLAminus -143.78, 172.36 63.44, 117.05 -123.51, 20.44 290.83, 101.94 -64.96, -18.67 in-in in 8.367 Saltbr-in 2.945 HRD-in -78.34, -51.59 77.34, 0.24 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.63, 92.97 APE9-dihe-na 149.06, -156.59 APE8-dihe-in -100.96, 114.13 APE8-rot-in 309.57 APE67-dihe-in -57.69, -42.62 -43.66, -38.84 APE12-dist-in 12.886 APE11-dist-in 11.92 APE10-dist-in 6.378 APE9-dist-in 4.155 None None None XRAY 2.0 0.244 0.264 B 296 286 3 0 0 0 [[9, 275]] 1.0 3uyt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYTC P48730 4 294 415.0 0CK:295 Type1 Active DFGin 5.532 15.483 BLAminus -138.61, 175.24 64.91, 102.33 -113.46, 24.22 289.92, 94.05 -63.01, -34.95 in-in in 8.62 Saltbr-in 3.217 HRD-in -72.73, -40.93 68.45, -2.11 in-in-in SNCiii in-in ActLoopNT-in 3.078 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.52, 137.99 APE9-dihe-na 115.79, -168.26 APE8-dihe-in -90.1, 119.0 APE8-rot-in 305.56 APE67-dihe-in -66.15, -27.91 -51.09, -29.22 APE12-dist-in 11.702 APE11-dist-in 11.708 APE10-dist-in 5.903 APE9-dist-in 3.838 None None None XRAY 2.0 0.244 0.264 C 296 286 5 0 0 5 [[9, 275]] 1.0 3uyt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UZPA P48730 3 294 415.0 0CK:295 Type1 Active DFGin 5.661 14.832 BLAminus -134.7, 173.74 69.19, 94.06 -102.81, 19.82 288.11, 111.94 -54.7, -37.81 in-in in 8.555 Saltbr-in 2.607 HRD-in -74.71, -48.25 74.53, -1.72 in-in-in SNCiii in-in ActLoopNT-in 2.938 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.7, 101.99 APE9-dihe-na 139.12, -156.68 APE8-dihe-in -102.2, 123.58 APE8-rot-in 298.11 APE67-dihe-in -52.36, -37.32 -50.21, -43.05 APE12-dist-in 12.672 APE11-dist-in 11.791 APE10-dist-in 6.402 APE9-dist-in 3.527 None None None XRAY 1.94 0.222 0.237 A 296 292 0 0 0 0 [[9, 275]] 1.0 3uzp Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UZPB P48730 3 294 415.0 0CK:295 Type1 Active DFGin 5.908 15.464 BLAminus -139.62, -179.78 62.23, 101.11 -114.8, 18.24 283.45, 104.48 -58.48, -26.44 in-in in 9.492 Saltbr-in 3.594 HRD-in -70.0, -50.75 77.55, -9.13 in-in-in SNCiii in-in ActLoopNT-in 2.867 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.19, 122.16 APE9-dihe-na 123.24, -159.55 APE8-dihe-in -115.76, 127.13 APE8-rot-in 299.41 APE67-dihe-in -56.38, -38.46 -53.95, -40.13 APE12-dist-in 11.194 APE11-dist-in 11.725 APE10-dist-in 6.221 APE9-dist-in 3.676 None None None XRAY 1.94 0.222 0.237 B 296 284 8 0 0 0 [[9, 275]] 1.0 3uzp Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4HGTB P48730 2 292 415.0 15G:301 Type1 Active DFGin 5.952 14.705 BLAminus -132.84, 173.91 65.29, 88.38 -100.07, 21.04 283.75, 100.66 -60.36, -23.77 in-in in 7.949 Saltbr-in 2.937 HRD-in -80.87, -49.33 71.68, 6.17 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.78, 107.2 APE9-dihe-na 146.92, -145.17 APE8-dihe-in -124.2, 122.26 APE8-rot-in 267.86 APE67-dihe-in -56.15, -40.08 -47.18, -38.14 APE12-dist-in 11.727 APE11-dist-in 12.247 APE10-dist-in 6.687 APE9-dist-in 3.634 None None None XRAY 1.8 0.24 999.0 B 296 280 11 0 0 0 [[9, 275]] 1.0 4hgt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4HNFA P48730 3 294 415.0 16W:301 Type1 Active DFGin 6.575 15.804 BLAminus -129.62, -172.35 54.61, 82.41 -100.04, 26.99 293.51, 69.72 -59.68, -32.76 in-in in 8.617 Saltbr-in 3.254 HRD-in -66.07, -51.92 76.62, -0.09 in-in-in SNCiii in-in ActLoopNT-in 3.142 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 21.82 APE9-dihe-na -154.45, -143.25 APE8-dihe-in -85.78, 141.82 APE8-rot-in 301.59 APE67-dihe-in -65.11, -35.21 -83.43, -20.7 APE12-dist-in 13.022 APE11-dist-in 12.366 APE10-dist-in 7.147 APE9-dist-in 4.202 None None None XRAY 2.07 0.241 0.274 A 296 289 3 0 0 0 [[9, 275]] 1.0 4hnf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8VXFA P48730 4 298 415.0 A1AD8:301 Type1 Active DFGin 5.913 14.514 BLAminus -129.71, -178.22 61.03, 74.13 -90.6, 25.58 297.09, 127.44 -66.39, -39.14 in-in in 8.04 Saltbr-in 2.628 HRD-in -70.13, -47.31 64.93, 7.47 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.9, 115.78 APE9-dihe-na 125.37, 178.72 APE8-dihe-in -73.6, 131.81 APE8-rot-in 292.64 APE67-dihe-in -59.57, -36.01 -65.35, -39.56 APE12-dist-in 10.879 APE11-dist-in 11.888 APE10-dist-in 6.111 APE9-dist-in 3.896 None None CSO71 XRAY 2.28 0.228 0.271 A 300 290 5 0 0 0 [[9, 275]] 1.0 8vxf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8VXFB P48730 1 293 415.0 A1AD8:301 Type1 Active DFGin 6.1 14.996 BLAminus -135.43, 179.54 60.46, 71.85 -84.36, 20.57 294.99, 103.53 -64.07, -35.46 in-in in 7.944 Saltbr-in 2.702 HRD-in -73.22, -53.58 69.54, 9.3 in-in-in SNCiii in-in ActLoopNT-in 2.736 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -87.76, 115.91 APE9-dihe-na 129.1, -158.3 APE8-dihe-in -97.01, 130.38 APE8-rot-in 323.35 APE67-dihe-in -60.35, -42.07 -72.75, -30.86 APE12-dist-in 11.43 APE11-dist-in 12.092 APE10-dist-in 6.268 APE9-dist-in 4.473 None None None XRAY 2.28 0.228 0.271 B 300 288 5 0 0 0 [[9, 275]] 1.0 8vxf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVB P48730 8 294 415.0 D5Q:301 Type1 Active DFGin 5.737 14.961 BLAminus -131.59, 168.24 73.3, 96.74 -107.44, 22.04 293.08, 97.39 -64.43, -25.64 in-in in 8.317 Saltbr-in 2.794 HRD-in -81.79, -49.07 72.49, 10.59 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.51, 119.45 APE9-dihe-na 118.74, -165.96 APE8-dihe-in -84.66, 139.43 APE8-rot-in 317.86 APE67-dihe-in -59.35, -40.52 -71.07, -35.78 APE12-dist-in 12.332 APE11-dist-in 11.984 APE10-dist-in 6.359 APE9-dist-in 4.004 None None None XRAY 2.154 0.173 0.192 B 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVD P48730 8 294 415.0 D5Q:301 Type1 Active DFGin 5.649 14.92 BLAminus -130.27, 169.09 73.19, 96.34 -107.09, 21.82 293.69, 97.37 -65.13, -25.84 in-in in 8.321 Saltbr-in 2.828 HRD-in -81.65, -48.96 71.89, 10.75 in-in-in SNCiii in-in ActLoopNT-in 2.898 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.39, -36.96 APE9-dihe-na -78.91, -162.23 APE8-dihe-in -81.37, 139.78 APE8-rot-in 305.31 APE67-dihe-in -59.04, -40.2 -68.84, -34.55 APE12-dist-in 11.976 APE11-dist-in 11.838 APE10-dist-in 6.137 APE9-dist-in 3.591 None None None XRAY 2.154 0.173 0.192 D 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVE P48730 8 294 415.0 D5Q:301 Type1 Active DFGin 5.791 14.918 BLAminus -131.33, 167.82 73.19, 96.43 -108.05, 21.28 293.17, 96.99 -65.15, -25.25 in-in in 8.304 Saltbr-in 2.81 HRD-in -81.43, -48.77 72.2, 11.06 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.94, 80.73 APE9-dihe-na 158.19, -165.3 APE8-dihe-in -84.27, 138.68 APE8-rot-in 301.84 APE67-dihe-in -58.32, -40.17 -70.07, -35.1 APE12-dist-in 12.322 APE11-dist-in 11.724 APE10-dist-in 6.16 APE9-dist-in 3.977 None None None XRAY 2.154 0.173 0.192 E 314 287 0 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5OKTA P48730 4 294 415.0 9XK:301 Type1 Active DFGin 6.162 14.659 BLAminus -133.28, 170.74 70.01, 89.31 -99.0, 19.37 294.41, 97.23 -61.59, -31.32 in-in in 8.04 Saltbr-in 2.927 HRD-in -77.86, -49.22 74.22, 0.79 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.17, 82.01 APE9-dihe-na 156.53, -168.77 APE8-dihe-in -81.75, 134.56 APE8-rot-in 311.88 APE67-dihe-in -58.69, -40.95 -68.59, -35.26 APE12-dist-in 12.888 APE11-dist-in 12.07 APE10-dist-in 6.617 APE9-dist-in 3.899 None TPO220 TPO220 XRAY 2.13 0.194 0.221 A 314 286 5 0 0 5 [[9, 275]] 1.0 5okt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5OKTC P48730 4 294 415.0 9XK:301 Type1 Active DFGin 6.083 14.872 BLAminus -137.28, 172.91 70.72, 87.04 -99.3, 19.0 294.7, 94.59 -62.74, -31.92 in-in in 8.117 Saltbr-in 2.573 HRD-in -77.69, -49.38 74.02, -0.1 in-in-in SNCiii in-in ActLoopNT-in 2.849 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.15, 136.58 APE9-dihe-na 93.44, -169.87 APE8-dihe-in -82.53, 136.41 APE8-rot-in 312.32 APE67-dihe-in -57.5, -41.07 -68.78, -35.33 APE12-dist-in 12.445 APE11-dist-in 12.119 APE10-dist-in 6.693 APE9-dist-in 3.421 None None None XRAY 2.13 0.194 0.221 C 314 285 6 0 0 0 [[9, 275]] 1.0 5okt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5OKTD P48730 3 294 415.0 9XK:301 Type1 Active DFGin 6.062 14.744 BLAminus -137.52, 172.23 70.39, 87.93 -98.16, 19.61 294.71, 94.98 -62.25, -31.9 in-in in 8.107 Saltbr-in 2.861 HRD-in -77.53, -49.31 73.84, 0.69 in-in-in SNCiii in-in ActLoopNT-in 2.822 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.67, 126.53 APE9-dihe-na 102.05, -168.99 APE8-dihe-in -81.94, 134.78 APE8-rot-in 312.39 APE67-dihe-in -57.6, -41.02 -69.15, -35.23 APE12-dist-in 12.39 APE11-dist-in 12.149 APE10-dist-in 6.705 APE9-dist-in 3.71 None None None XRAY 2.13 0.194 0.221 D 314 282 10 0 0 0 [[9, 275]] 1.0 5okt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6F1WA P48730 3 292 415.0 CG5:308 Type1 Active DFGin 5.617 15.345 BLAminus -131.72, 170.95 75.82, 94.85 -108.5, 22.63 294.72, 95.1 -64.52, -24.91 in-in in 9.034 Saltbr-in 3.495 HRD-in -79.29, -50.31 74.39, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.841 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -107.6, 102.07 APE9-dihe-na 145.81, -161.66 APE8-dihe-in -102.55, 122.91 APE8-rot-in 308.33 APE67-dihe-in -56.46, -36.56 -57.9, -38.78 APE12-dist-in 11.928 APE11-dist-in 11.655 APE10-dist-in 6.007 APE9-dist-in 3.737 None TPO220 TPO220 XRAY 1.864 0.182 0.206 A 314 285 5 0 0 0 [[9, 275]] 1.0 6f1w Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6F1WB P48730 1 291 415.0 CG5:309 Type1 Active DFGin 5.64 15.419 BLAminus -133.14, 170.48 75.33, 95.98 -108.41, 23.26 294.11, 96.58 -64.58, -24.61 in-in in 9.202 Saltbr-in 3.422 HRD-in -79.25, -49.88 75.06, 6.23 in-in-in SNCiii in-in ActLoopNT-in 2.85 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.07, 103.05 APE9-dihe-na 146.18, -161.66 APE8-dihe-in -103.19, 123.14 APE8-rot-in 307.68 APE67-dihe-in -56.96, -36.58 -57.24, -38.6 APE12-dist-in 12.077 APE11-dist-in 11.827 APE10-dist-in 6.192 APE9-dist-in 3.705 None None None XRAY 1.864 0.182 0.206 B 314 280 11 0 0 0 [[9, 275]] 1.0 6f1w Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6F26A P48730 3 293 415.0 C9Z:314 Type1 Active DFGin 5.759 15.483 BLAminus -132.42, 172.37 74.42, 91.28 -106.08, 19.87 292.81, 96.43 -64.71, -22.22 in-in in 9.087 Saltbr-in 3.426 HRD-in -79.24, -49.47 75.74, 5.24 in-in-in SNCiii in-in ActLoopNT-in 2.843 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.38, 102.1 APE9-dihe-na 153.19, -157.67 APE8-dihe-in -110.24, 124.98 APE8-rot-in 305.28 APE67-dihe-in -58.18, -34.02 -57.89, -38.29 APE12-dist-in 11.56 APE11-dist-in 11.694 APE10-dist-in 5.991 APE9-dist-in 3.545 None None None XRAY 1.83 0.19 0.209 A 314 280 11 0 0 0 [[9, 275]] 1.0 6f26 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6F26B P48730 3 293 415.0 C9Z:307 Type1 Active DFGin 5.658 15.526 BLAminus -131.85, 172.58 74.83, 92.21 -105.55, 19.73 292.1, 96.5 -64.53, -21.81 in-in in 9.286 Saltbr-in 3.199 HRD-in -79.15, -49.63 75.68, 5.29 in-in-in SNCiii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.91, 102.25 APE9-dihe-na 153.59, -157.23 APE8-dihe-in -110.24, 124.2 APE8-rot-in 305.62 APE67-dihe-in -58.5, -35.79 -58.44, -37.5 APE12-dist-in 11.609 APE11-dist-in 11.683 APE10-dist-in 6.003 APE9-dist-in 3.574 None None None XRAY 1.83 0.19 0.209 B 314 281 10 0 0 0 [[9, 275]] 1.0 6f26 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6HMPA P48730 8 294 415.0 GEW:301 Type1 Active DFGin 5.852 14.825 BLAminus -132.93, 168.87 75.84, 99.76 -110.81, 21.42 294.49, 101.21 -61.62, -29.55 in-in in 8.336 Saltbr-in 2.749 HRD-in -83.25, -49.35 75.12, 6.17 in-in-in SNCiii in-in ActLoopNT-in 2.812 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.37, 137.14 APE9-dihe-na 102.67, -169.04 APE8-dihe-in -88.64, 128.2 APE8-rot-in 309.71 APE67-dihe-in -55.63, -40.75 -60.69, -38.48 APE12-dist-in 12.788 APE11-dist-in 12.341 APE10-dist-in 6.674 APE9-dist-in 3.818 None None None XRAY 2.039 0.187 0.219 A 314 286 1 0 0 0 [[9, 275]] 1.0 6hmp Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6HMPB P48730 1 293 415.0 GEW:301 Type1 Active DFGin 5.703 14.778 BLAminus -133.94, 168.26 76.06, 99.73 -110.46, 21.48 293.68, 101.03 -62.95, -28.85 in-in in 8.204 Saltbr-in 2.664 HRD-in -81.34, -48.98 74.24, 7.39 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.0, 132.29 APE9-dihe-na 101.61, -168.87 APE8-dihe-in -87.9, 130.96 APE8-rot-in 309.49 APE67-dihe-in -55.04, -40.56 -59.88, -37.12 APE12-dist-in 11.739 APE11-dist-in 11.823 APE10-dist-in 6.199 APE9-dist-in 3.617 None None None XRAY 2.039 0.187 0.219 B 314 278 15 0 0 0 [[9, 275]] 1.0 6hmp Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6HMRA P48730 7 294 415.0 GE5:60301 Type1 Active DFGin 5.902 14.826 BLAminus -129.77, 165.39 78.39, 101.15 -107.5, 20.0 293.32, 102.36 -64.81, -25.32 in-in in 8.284 Saltbr-in 2.749 HRD-in -83.07, -49.96 76.13, 7.49 in-in-in SNCiii in-in ActLoopNT-in 2.825 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -105.61, 123.18 APE9-dihe-na 112.73, -152.95 APE8-dihe-in -99.78, 125.38 APE8-rot-in 305.84 APE67-dihe-in -55.81, -38.54 -61.27, -36.97 APE12-dist-in 12.625 APE11-dist-in 12.31 APE10-dist-in 6.77 APE9-dist-in 3.973 None None None XRAY 1.782 0.176 0.199 A 314 287 1 0 0 0 [[9, 275]] 1.0 6hmr Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6HMRB P48730 1 293 415.0 GE5:60301 Type1 Active DFGin 5.728 14.821 BLAminus -132.18, 166.65 79.25, 99.25 -107.58, 20.5 292.42, 101.79 -65.16, -22.71 in-in in 8.173 Saltbr-in 2.632 HRD-in -83.94, -50.09 75.09, 8.55 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.7, -50.27 APE9-dihe-na -84.81, -142.78 APE8-dihe-in -93.52, 127.66 APE8-rot-in 306.5 APE67-dihe-in -55.61, -39.37 -59.1, -37.12 APE12-dist-in 12.085 APE11-dist-in 11.829 APE10-dist-in 6.028 APE9-dist-in 3.927 None None None XRAY 1.782 0.176 0.199 B 314 279 14 0 0 0 [[9, 275]] 1.0 6hmr Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7NZYA P48730 4 294 415.0 UX2:301 Type1 Active DFGin 6.559 14.886 BLAminus -133.96, 167.79 70.83, 96.95 -106.29, 25.68 291.55, 83.04 -66.18, -24.86 in-in in 8.075 Saltbr-in 3.016 HRD-in -78.9, -49.6 75.24, 4.27 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.05, -40.09 APE9-dihe-na -82.1, -153.64 APE8-dihe-in -93.91, 137.61 APE8-rot-in 310.79 APE67-dihe-in -56.87, -39.19 -67.48, -35.89 APE12-dist-in 12.805 APE11-dist-in 11.473 APE10-dist-in 5.963 APE9-dist-in 3.855 None TPO220 TPO220 XRAY 1.85 0.205 0.229 A 314 286 5 0 0 5 [[9, 275]] 1.0 7nzy Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7NZYC P48730 3 294 415.0 UX2:301 Type1 Active DFGin 6.218 14.791 BLAminus -136.64, 167.98 72.37, 97.2 -107.4, 23.39 293.87, 95.12 -65.21, -24.66 in-in in 8.1 Saltbr-in 2.77 HRD-in -79.48, -51.87 75.69, 7.23 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -107.57, 101.78 APE9-dihe-na 127.22, -154.68 APE8-dihe-in -96.66, 135.72 APE8-rot-in 310.5 APE67-dihe-in -59.23, -39.9 -66.83, -34.06 APE12-dist-in 12.38 APE11-dist-in 11.857 APE10-dist-in 6.483 APE9-dist-in 3.779 None TPO220 TPO220 XRAY 1.85 0.205 0.229 C 314 283 9 0 0 0 [[9, 275]] 1.0 7nzy Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7NZYD P48730 3 294 415.0 UX2:301 Type1 Active DFGin 6.464 14.937 BLAminus -138.25, 167.9 72.5, 98.99 -108.83, 24.01 292.41, 92.73 -66.77, -25.48 in-in in 8.132 Saltbr-in 2.824 HRD-in -79.6, -51.19 75.63, 6.47 in-in-in SNCiii in-in ActLoopNT-in 2.817 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.03, 112.87 APE9-dihe-na 117.74, -155.19 APE8-dihe-in -96.88, 133.52 APE8-rot-in 309.51 APE67-dihe-in -57.81, -40.27 -67.41, -34.56 APE12-dist-in 12.598 APE11-dist-in 12.323 APE10-dist-in 6.762 APE9-dist-in 3.921 None TPO220 TPO220 XRAY 1.85 0.205 0.229 D 314 285 7 0 0 0 [[9, 275]] 1.0 7nzy Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBCA P48730 2 293 415.0 1QJ:401 Type1 Active DFGin 6.144 15.135 BLAminus -135.05, 177.16 64.97, 92.79 -104.57, 19.94 289.19, 98.91 -62.1, -27.64 in-in in 8.602 Saltbr-in 3.125 HRD-in -76.21, -47.92 72.55, 1.87 in-in-in SNCiii in-in ActLoopNT-in 2.883 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.96, 99.19 APE9-dihe-na 142.25, -165.38 APE8-dihe-in -94.12, 126.6 APE8-rot-in 308.27 APE67-dihe-in -52.38, -38.16 -56.17, -42.26 APE12-dist-in 11.369 APE11-dist-in 11.684 APE10-dist-in 5.988 APE9-dist-in 3.794 None None None XRAY 1.98 0.186 0.215 A 317 288 4 0 0 0 [[9, 275]] 1.0 4kbc Homo sapiens CK1_CSNK1D_HUMAN CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBCB P48730 1 291 415.0 1QJ:401 Type1 Active DFGin 6.234 14.815 BLAminus -134.33, 176.57 61.14, 97.98 -105.5, 17.63 290.56, 99.02 -63.05, -28.6 in-in in 8.028 Saltbr-in 2.783 HRD-in -76.33, -48.22 73.21, 2.14 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.52, 104.52 APE9-dihe-na 134.47, -165.32 APE8-dihe-in -95.88, 127.1 APE8-rot-in 306.97 APE67-dihe-in -51.8, -38.48 -58.36, -41.31 APE12-dist-in 11.805 APE11-dist-in 11.967 APE10-dist-in 6.401 APE9-dist-in 3.807 None None None XRAY 1.98 0.186 0.215 B 317 277 11 0 0 0 [[9, 275]] 1.0 4kbc Homo sapiens CK1_CSNK1D_HUMAN CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TN6A P48730 2 293 415.0 PFO:401 Type1 Active DFGin 5.994 14.999 BLAminus -131.86, 176.23 68.13, 89.84 -98.73, 20.71 292.85, 102.42 -60.06, -32.67 in-in in 8.564 Saltbr-in 3.478 HRD-in -77.93, -48.08 67.27, 5.51 in-in-in SNCiii in-in ActLoopNT-in 2.982 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.37, 100.66 APE9-dihe-na 124.79, -165.82 APE8-dihe-in -87.49, 129.31 APE8-rot-in 310.24 APE67-dihe-in -53.32, -42.74 -57.19, -41.79 APE12-dist-in 11.521 APE11-dist-in 11.595 APE10-dist-in 6.051 APE9-dist-in 3.859 None None None XRAY 2.41 0.19 0.239 A 318 292 0 0 0 0 [[9, 275]] 1.0 4tn6 Homo sapiens CK1_CSNK1D_HUMAN CK1 2e-122 413.5 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TW9A P48730 2 295 415.0 386:1010 Type1 Active DFGin 6.697 14.583 BLAminus -136.97, 175.66 62.22, 78.84 -97.46, 44.93 290.89, 111.01 -92.15, -19.29 in-in in 7.996 Saltbr-in 2.389 HRD-in -80.17, -50.66 73.37, -1.23 in-in-in SNCiii in-in ActLoopNT-in 2.784 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.1, 128.87 APE9-dihe-na 98.06, 169.96 APE8-dihe-in -77.13, 124.79 APE8-rot-in 325.52 APE67-dihe-in -48.58, -35.63 -42.76, -54.19 APE12-dist-in 11.915 APE11-dist-in 11.774 APE10-dist-in 6.514 APE9-dist-in 3.619 R13N None None XRAY 2.4 0.21 0.298 A 295 290 4 0 0 0 [[9, 275]] 1.0 4tw9 Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TW9B P48730 1 295 415.0 386:1007 Type1 Active DFGin 6.721 14.492 BLAminus -131.65, 171.29 75.31, 83.03 -107.11, 28.16 296.33, 79.52 -70.97, -25.3 in-in in 7.827 Saltbr-in 2.545 HRD-in -75.47, -49.16 73.76, 6.22 in-in-in SNCiii in-in ActLoopNT-in 2.975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.99, 118.4 APE9-dihe-na 97.98, 177.61 APE8-dihe-in -69.71, 139.17 APE8-rot-in 303.41 APE67-dihe-in -54.9, -35.25 -78.5, -33.85 APE12-dist-in 12.475 APE11-dist-in 11.674 APE10-dist-in 6.451 APE9-dist-in 3.592 R13N None None XRAY 2.4 0.21 0.298 B 295 289 6 0 0 0 [[9, 275]] 1.0 4tw9 Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TWCA P48730 2 295 415.0 37J:1007 Type1 Active DFGin 5.789 14.614 BLAminus -135.4, 171.43 74.73, 98.94 -108.48, 20.23 290.12, 99.35 -60.18, -25.97 in-in in 8.185 Saltbr-in 2.802 HRD-in -80.26, -49.62 74.67, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.85, 127.15 APE9-dihe-na 100.6, 178.11 APE8-dihe-in -77.16, 129.65 APE8-rot-in 307.18 APE67-dihe-in -54.54, -41.21 -56.81, -38.63 APE12-dist-in 12.174 APE11-dist-in 11.858 APE10-dist-in 6.354 APE9-dist-in 3.502 R13N None None XRAY 1.7 0.165 0.205 A 295 293 1 0 0 0 [[9, 275]] 1.0 4twc Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4TWCB P48730 1 295 415.0 37J:1008 Type1 Active DFGin 6.186 14.647 BLAminus -137.25, 168.94 78.2, 99.05 -108.33, 17.1 288.71, 108.96 -59.97, -32.8 in-in in 8.033 Saltbr-in 2.803 HRD-in -77.54, -49.39 71.05, 0.74 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.24, 128.18 APE9-dihe-na 92.69, -176.23 APE8-dihe-in -79.0, 129.98 APE8-rot-in 306.66 APE67-dihe-in -54.91, -40.74 -63.37, -37.19 APE12-dist-in 12.252 APE11-dist-in 11.648 APE10-dist-in 6.316 APE9-dist-in 3.571 R13N None None XRAY 1.7 0.165 0.205 B 295 292 3 0 0 0 [[9, 275]] 1.0 4twc Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6GZMB P48730 1 295 415.0 LCI:1003 Type1 Active DFGin 6.029 14.94 BLAminus -133.71, 166.42 75.71, 96.43 -105.56, 19.57 289.87, 100.18 -66.61, -26.34 in-in in 8.2 Saltbr-in 2.978 HRD-in -81.5, -50.17 76.38, 3.88 in-in-in SNCiii in-in ActLoopNT-in 2.885 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.67, 144.06 APE9-dihe-na 111.45, -147.04 APE8-dihe-in -123.08, 119.05 APE8-rot-in 301.33 APE67-dihe-in -54.27, -40.27 -57.58, -37.53 APE12-dist-in 11.578 APE11-dist-in 12.532 APE10-dist-in 6.467 APE9-dist-in 3.981 R13N None None XRAY 1.59 0.192 0.25 B 295 295 0 0 0 0 [[9, 275]] 1.0 6gzm Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KB8B P48730 3 293 415.0 1QO:401 Type1 Active DFGin 5.967 14.913 BLAminus -134.33, 177.52 61.96, 98.8 -107.18, 20.23 290.65, 100.47 -61.53, -33.77 in-in in 8.219 Saltbr-in 2.844 HRD-in -73.63, -48.77 75.48, -5.09 in-in-in SNCiii in-in ActLoopNT-in 2.927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.58, 107.53 APE9-dihe-na 136.09, -158.34 APE8-dihe-in -103.95, 128.43 APE8-rot-in 304.04 APE67-dihe-in -53.87, -40.76 -52.99, -42.94 APE12-dist-in 11.513 APE11-dist-in 11.86 APE10-dist-in 6.123 APE9-dist-in 3.572 None None None XRAY 1.95 0.207 0.232 B 331 285 6 0 0 0 [[9, 275]] 1.0 4kb8 Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KB8C P48730 7 293 415.0 1QN:401 Type1 Active DFGin 5.968 14.825 BLAminus -127.94, 175.57 64.97, 98.7 -108.35, 19.36 290.2, 100.79 -61.94, -33.27 in-in in 8.245 Saltbr-in 2.856 HRD-in -75.11, -48.96 76.7, -5.84 in-in-in SNCiii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.1, 109.67 APE9-dihe-na 130.48, -159.04 APE8-dihe-in -102.61, 128.45 APE8-rot-in 304.06 APE67-dihe-in -54.95, -40.0 -54.23, -41.49 APE12-dist-in 11.374 APE11-dist-in 11.832 APE10-dist-in 6.157 APE9-dist-in 3.556 None None None XRAY 1.95 0.207 0.232 C 331 277 10 0 0 10 [[9, 275]] 1.0 4kb8 Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KB8D P48730 3 293 415.0 1QO:401 Type1 Active DFGin 5.976 14.883 BLAminus -137.08, 175.26 62.92, 98.03 -106.78, 19.33 290.69, 100.97 -61.01, -34.47 in-in in 8.219 Saltbr-in 2.83 HRD-in -73.79, -47.9 74.68, -5.6 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.75, 105.76 APE9-dihe-na 137.74, -159.08 APE8-dihe-in -102.58, 128.72 APE8-rot-in 303.15 APE67-dihe-in -54.52, -40.24 -53.18, -41.69 APE12-dist-in 11.982 APE11-dist-in 11.913 APE10-dist-in 6.189 APE9-dist-in 3.587 None None None XRAY 1.95 0.207 0.232 D 331 278 13 0 0 3 [[9, 275]] 1.0 4kb8 Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBAB P48730 3 293 415.0 1QM:401 Type1 Active DFGin 5.881 14.872 BLAminus -129.74, 173.49 62.39, 106.5 -115.95, 19.82 290.11, 105.76 -62.08, -34.97 in-in in 8.231 Saltbr-in 2.765 HRD-in -71.85, -51.41 76.93, -3.35 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.73, 105.33 APE9-dihe-na 138.05, -162.68 APE8-dihe-in -99.65, 127.15 APE8-rot-in 303.86 APE67-dihe-in -59.88, -40.85 -56.13, -36.41 APE12-dist-in 11.4 APE11-dist-in 11.655 APE10-dist-in 6.019 APE9-dist-in 3.523 None None None XRAY 1.98 0.21 0.237 B 331 285 6 0 0 0 [[9, 275]] 1.0 4kba Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBAC P48730 7 293 415.0 1QM:401 Type1 Active DFGin 5.934 14.746 BLAminus -127.94, 172.81 65.26, 104.02 -113.85, 19.72 291.07, 106.01 -63.19, -33.18 in-in in 7.993 Saltbr-in 2.711 HRD-in -73.02, -52.06 78.99, -4.92 in-in-in SNCiii in-in ActLoopNT-in 2.925 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.53, 105.58 APE9-dihe-na 138.04, -161.96 APE8-dihe-in -100.6, 126.19 APE8-rot-in 304.81 APE67-dihe-in -58.93, -39.59 -56.36, -37.06 APE12-dist-in 11.703 APE11-dist-in 11.719 APE10-dist-in 6.02 APE9-dist-in 3.541 None None None XRAY 1.98 0.21 0.237 C 331 277 10 0 0 10 [[9, 275]] 1.0 4kba Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBAD P48730 3 293 415.0 1QM:401 Type1 Active DFGin 5.906 14.856 BLAminus -129.34, 172.61 62.47, 106.14 -113.79, 20.2 290.42, 106.77 -61.94, -35.25 in-in in 8.227 Saltbr-in 2.847 HRD-in -72.46, -51.24 77.53, -4.45 in-in-in SNCiii in-in ActLoopNT-in 2.921 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.9, 105.19 APE9-dihe-na 137.57, -162.53 APE8-dihe-in -99.78, 126.75 APE8-rot-in 303.64 APE67-dihe-in -59.4, -40.4 -55.75, -36.15 APE12-dist-in 11.687 APE11-dist-in 11.762 APE10-dist-in 6.101 APE9-dist-in 3.538 None None None XRAY 1.98 0.21 0.237 D 331 274 17 0 0 7 [[9, 275]] 1.0 4kba Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBKA P48730 3 293 415.0 1QG:401 Type1 Active DFGin 5.844 14.976 BLAminus -131.67, 175.29 64.95, 97.7 -105.98, 20.74 289.68, 102.64 -60.84, -32.86 in-in in 8.386 Saltbr-in 2.915 HRD-in -79.36, -48.84 76.24, -1.03 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.11, 44.14 APE9-dihe-na -164.81, -162.01 APE8-dihe-in -83.41, 128.52 APE8-rot-in 306.95 APE67-dihe-in -54.65, -40.65 -56.32, -40.55 APE12-dist-in 11.982 APE11-dist-in 11.806 APE10-dist-in 6.374 APE9-dist-in 3.651 None None None XRAY 2.1 0.193 0.225 A 331 283 8 0 0 0 [[9, 275]] 1.0 4kbk Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBKB P48730 3 293 415.0 1QG:401 Type1 Active DFGin 5.87 14.907 BLAminus -130.17, 174.94 66.33, 98.19 -106.72, 21.44 289.55, 101.16 -63.29, -31.57 in-in in 8.368 Saltbr-in 2.965 HRD-in -71.92, -49.63 76.82, -1.31 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.91, 121.45 APE9-dihe-na 106.7, -175.66 APE8-dihe-in -76.31, 127.18 APE8-rot-in 313.52 APE67-dihe-in -54.93, -40.02 -57.76, -39.93 APE12-dist-in 12.291 APE11-dist-in 12.01 APE10-dist-in 6.338 APE9-dist-in 3.745 None None None XRAY 2.1 0.193 0.225 B 331 289 2 0 0 2 [[9, 275]] 1.0 4kbk Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBKC P48730 4 293 415.0 1QG:401 Type1 Active DFGin 5.855 14.967 BLAminus -129.85, 175.61 65.46, 97.52 -106.96, 21.33 289.98, 100.83 -62.95, -31.03 in-in in 8.373 Saltbr-in 2.945 HRD-in -72.81, -49.86 76.81, -1.6 in-in-in SNCiii in-in ActLoopNT-in 2.929 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -97.84, 118.02 APE9-dihe-na 109.84, -172.07 APE8-dihe-in -80.07, 126.56 APE8-rot-in 311.91 APE67-dihe-in -53.2, -40.67 -57.15, -41.1 APE12-dist-in 12.141 APE11-dist-in 11.935 APE10-dist-in 6.407 APE9-dist-in 3.77 None None None XRAY 2.1 0.193 0.225 C 331 280 10 0 0 7 [[9, 275]] 1.0 4kbk Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5W4WA P48730 3 293 415.0 9WG:4001 Type1 Active DFGin 5.986 15.195 BLAminus -131.25, 176.25 64.66, 92.1 -102.54, 20.05 287.74, 100.7 -63.95, -24.57 in-in in 8.427 Saltbr-in 2.856 HRD-in -71.78, -50.33 73.01, 0.22 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.58, 102.08 APE9-dihe-na 131.12, -154.11 APE8-dihe-in -101.21, 128.13 APE8-rot-in 305.7 APE67-dihe-in -58.83, -38.87 -58.35, -35.99 APE12-dist-in 11.551 APE11-dist-in 11.882 APE10-dist-in 6.338 APE9-dist-in 3.665 None None None XRAY 1.99 0.181 0.215 A 331 291 0 0 0 0 [[9, 275]] 1.0 5w4w Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5W4WB P48730 3 293 415.0 9WG:4001 Type1 Active DFGin 5.978 15.223 BLAminus -131.04, 176.44 64.42, 92.61 -102.67, 20.2 288.33, 100.31 -65.39, -24.22 in-in in 8.487 Saltbr-in 2.794 HRD-in -73.43, -49.34 72.38, -0.15 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.22, 101.23 APE9-dihe-na 132.31, -153.66 APE8-dihe-in -102.36, 127.37 APE8-rot-in 304.5 APE67-dihe-in -57.1, -37.55 -57.06, -37.79 APE12-dist-in 11.602 APE11-dist-in 11.913 APE10-dist-in 6.346 APE9-dist-in 3.698 None None None XRAY 1.99 0.181 0.215 B 331 291 0 0 0 0 [[9, 275]] 1.0 5w4w Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5W4WC P48730 4 293 415.0 9WG:401 Type1 Active DFGin 6.004 15.045 BLAminus -128.72, 177.08 64.84, 92.61 -103.51, 20.15 288.9, 99.1 -59.9, -30.22 in-in in 8.603 Saltbr-in 3.148 HRD-in -73.53, -49.07 71.4, 1.6 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.5, 101.03 APE9-dihe-na 131.64, -155.27 APE8-dihe-in -102.5, 129.0 APE8-rot-in 305.66 APE67-dihe-in -57.12, -38.65 -59.6, -37.26 APE12-dist-in 11.459 APE11-dist-in 11.894 APE10-dist-in 6.335 APE9-dist-in 3.663 None None None XRAY 1.99 0.181 0.215 C 331 284 6 0 0 6 [[9, 275]] 1.0 5w4w Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5W4WD P48730 3 293 415.0 9WG:401 Type1 Active DFGin 6.025 15.044 BLAminus -129.0, 176.14 65.59, 93.67 -104.32, 19.97 289.61, 99.52 -64.71, -24.69 in-in in 8.489 Saltbr-in 2.933 HRD-in -70.95, -50.23 72.86, 1.67 in-in-in SNCiii in-in ActLoopNT-in 2.946 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.11, 101.9 APE9-dihe-na 139.4, -155.09 APE8-dihe-in -103.26, 128.82 APE8-rot-in 306.45 APE67-dihe-in -58.65, -38.27 -59.32, -36.51 APE12-dist-in 11.213 APE11-dist-in 11.863 APE10-dist-in 6.064 APE9-dist-in 3.683 None None None XRAY 1.99 0.181 0.215 D 331 287 4 0 0 0 [[9, 275]] 1.0 5w4w Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RCHA P48730 2 294 415.0 K0B:310 Type1.5_Back Active DFGin 6.035 14.468 BLAminus -122.24, 159.67 82.29, 109.19 -106.33, 18.46 287.11, 119.74 -68.96, -18.8 in-in in 7.785 Saltbr-in 2.655 HRD-in -82.67, -47.67 69.74, 14.2 in-in-in SNCiii in-in ActLoopNT-in 2.847 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -106.54, -51.03 APE9-dihe-na -92.71, -155.88 APE8-dihe-in -77.58, 125.49 APE8-rot-in 293.15 APE67-dihe-in -52.81, -38.11 -57.21, -30.67 APE12-dist-in 11.686 APE11-dist-in 11.749 APE10-dist-in 5.801 APE9-dist-in 3.993 None None None XRAY 1.45 0.157 0.178 A 296 293 0 0 0 0 [[9, 275]] 1.0 6rch Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU7A P48730 3 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.392 15.125 BLAminus -134.23, -173.24 59.44, 80.86 -96.06, 22.96 285.76, 78.27 -62.92, -27.34 in-in in 7.971 Saltbr-in 2.803 HRD-in -82.18, -50.23 72.61, 5.15 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.24, 126.6 APE9-dihe-na 114.96, -145.11 APE8-dihe-in -115.28, 122.22 APE8-rot-in 302.31 APE67-dihe-in -56.73, -38.36 -50.64, -46.9 APE12-dist-in 12.381 APE11-dist-in 12.179 APE10-dist-in 6.834 APE9-dist-in 3.511 None None None XRAY 2.08 0.177 0.218 A 296 292 0 0 0 0 [[9, 275]] 1.0 6ru7 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU7B P48730 3 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.618 14.988 BLAminus -130.01, -176.4 60.72, 81.81 -97.28, 21.17 286.1, 78.89 -61.41, -29.58 in-in in 7.795 Saltbr-in 2.912 HRD-in -81.31, -50.84 72.75, 6.38 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.97, 131.36 APE9-dihe-na 113.79, -145.67 APE8-dihe-in -115.43, 125.17 APE8-rot-in 305.08 APE67-dihe-in -54.67, -36.6 -52.93, -49.24 APE12-dist-in 13.297 APE11-dist-in 12.156 APE10-dist-in 6.649 APE9-dist-in 3.527 None None None XRAY 2.08 0.177 0.218 B 296 288 4 0 0 4 [[9, 275]] 1.0 6ru7 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU8A P48730 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.425 15.156 BLAminus -131.62, -177.15 63.45, 81.35 -98.16, 25.89 286.32, 78.16 -68.14, -23.3 in-in in 7.926 Saltbr-in 2.803 HRD-in -87.78, -47.56 70.02, 4.06 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.49, 136.29 APE9-dihe-na 109.45, -154.85 APE8-dihe-in -109.19, 121.34 APE8-rot-in 302.42 APE67-dihe-in -58.68, -38.47 -55.68, -42.0 APE12-dist-in 13.563 APE11-dist-in 12.282 APE10-dist-in 6.892 APE9-dist-in 3.572 None None None XRAY 1.92 0.174 0.211 A 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU8B P48730 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.591 15.264 BLAminus -131.67, -177.68 64.26, 82.5 -98.0, 23.89 285.39, 79.53 -66.54, -22.27 in-in in 7.662 Saltbr-in 2.78 HRD-in -88.75, -48.7 67.58, 11.08 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.47, 142.8 APE9-dihe-na 95.33, -164.73 APE8-dihe-in -102.94, 120.03 APE8-rot-in 301.71 APE67-dihe-in -59.39, -37.33 -59.11, -40.45 APE12-dist-in 12.308 APE11-dist-in 12.295 APE10-dist-in 7.245 APE9-dist-in 3.892 None None None XRAY 1.92 0.174 0.211 B 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU8C P48730 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.558 14.983 BLAminus -128.29, -179.37 66.68, 80.46 -98.0, 22.92 288.66, 76.31 -64.33, -23.77 in-in in 7.948 Saltbr-in 2.77 HRD-in -82.99, -49.18 72.75, 4.46 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.59, 138.55 APE9-dihe-na 101.61, -152.03 APE8-dihe-in -108.82, 122.86 APE8-rot-in 298.47 APE67-dihe-in -58.74, -36.85 -58.82, -40.4 APE12-dist-in 13.04 APE11-dist-in 12.435 APE10-dist-in 6.868 APE9-dist-in 3.607 None None None XRAY 1.92 0.174 0.211 C 296 287 6 0 0 6 [[9, 275]] 1.0 6ru8 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU8D P48730 2 294 415.0 ADP:60301 Type1.5_Back Active DFGin 6.534 14.975 BLAminus -126.38, -177.59 65.46, 80.95 -97.97, 21.9 288.13, 75.77 -63.86, -25.32 in-in in 7.979 Saltbr-in 2.782 HRD-in -86.34, -48.63 71.97, 3.09 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.34, 138.88 APE9-dihe-na 102.71, -155.7 APE8-dihe-in -106.76, 124.41 APE8-rot-in 298.22 APE67-dihe-in -58.88, -36.36 -58.72, -41.76 APE12-dist-in 12.717 APE11-dist-in 12.352 APE10-dist-in 6.743 APE9-dist-in 3.59 None None None XRAY 1.92 0.174 0.211 D 296 293 0 0 0 0 [[9, 275]] 1.0 6ru8 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7GA P48730 8 294 415.0 AMP:303 ATPlike Inactive DFGin 6.503 15.21 BLAminus -125.58, -175.5 62.42, 84.62 -97.89, 21.28 284.93, 73.84 -62.65, -25.46 in-in in 8.252 Saltbr-in 3.016 HRD-in -80.32, -51.03 68.77, 15.13 in-in-out SNCiio in-out ActLoopNT-in 2.837 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.17, 158.18 APE9-dihe-na 70.26, -143.4 APE8-dihe-in -92.54, 123.25 APE8-rot-out 48.69 APE67-dihe-in -52.86, -40.08 -97.14, -14.35 APE12-dist-out 14.057 APE11-dist-in 12.931 APE10-dist-out 9.429 APE9-dist-out 8.015 None TPO220 TPO220 XRAY 1.7 0.173 0.208 A 296 287 0 0 0 0 [[9, 275]] 1.0 7p7g Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7P7GB P48730 7 293 415.0 AMP:307 ATPlike Inactive DFGin 6.484 14.825 BLAminus -126.09, 178.73 70.29, 86.32 -102.39, 14.25 288.72, 93.03 -61.48, -28.95 in-in in 8.084 Saltbr-in 3.028 HRD-in -71.5, -47.28 67.0, 16.77 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -110.74, 162.01 APE9-dihe-na -98.48, -144.78 APE8-dihe-in -45.03, 124.48 APE8-rot-out 164.69 APE67-dihe-in -57.08, -42.44 -74.38, -40.7 APE12-dist-in 7.209 APE11-dist-out 6.613 APE10-dist-out 8.393 APE9-dist-in 3.884 None TPO220 TPO220 XRAY 1.7 0.173 0.208 B 296 283 2 0 0 0 [[9, 275]] 1.0 7p7g Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5IH4A P48730 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.742 15.381 BLAminus -127.38, 171.98 74.1, 92.89 -102.61, 27.68 294.39, 95.11 -77.69, -29.22 in-out in 8.389 Saltbr-out 3.77 HRD-in -81.4, -50.53 75.25, -4.33 out-in-in SNCoii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.74, 138.15 APE9-dihe-na 95.04, -174.85 APE8-dihe-in -82.96, 136.47 APE8-rot-in 313.94 APE67-dihe-in -50.11, -38.92 -65.78, -39.41 APE12-dist-in 12.713 APE11-dist-in 11.94 APE10-dist-in 6.226 APE9-dist-in 3.836 None None None XRAY 1.9 0.193 0.227 A 294 287 6 0 0 0 [[9, 275]] 1.0 5ih4 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXOA P48730 2 292 415.0 No_ligand No_ligand Inactive DFGin 5.83 14.801 BLAminus -131.27, 169.62 69.74, 95.31 -105.42, 22.12 288.92, 95.11 -70.27, -22.72 in-in in 8.048 Saltbr-in 2.681 HRD-in -82.5, -47.16 68.42, 11.28 in-in-out SNCiio in-out ActLoopNT-in 2.936 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -109.35, -77.38 APE9-dihe-na -82.68, -147.73 APE8-dihe-in -72.83, 143.07 APE8-rot-out 203.92 APE67-dihe-in -63.17, -35.92 -67.57, -33.41 APE12-dist-in 11.432 APE11-dist-in 11.553 APE10-dist-in 5.961 APE9-dist-in 4.076 None None None XRAY 2.0 0.182 0.237 A 294 291 0 0 0 0 [[9, 275]] 1.0 6pxo Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXOB P48730 1 292 415.0 No_ligand No_ligand Inactive DFGin 5.933 14.982 BLAminus -130.18, 170.18 70.22, 97.25 -104.4, 22.76 289.31, 97.78 -67.1, -25.51 in-in in 8.079 Saltbr-in 2.613 HRD-in -79.64, -46.78 70.5, 7.47 in-in-out SNCiio in-out ActLoopNT-in 2.875 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -112.52, 160.14 APE9-dihe-na -85.26, -149.51 APE8-dihe-in -68.63, 139.98 APE8-rot-out 62.2 APE67-dihe-in -64.81, -35.43 -67.5, -33.21 APE12-dist-in 7.156 APE11-dist-out 6.557 APE10-dist-out 8.475 APE9-dist-in 4.062 None None None XRAY 2.0 0.182 0.237 B 294 292 0 0 0 0 [[9, 275]] 1.0 6pxo Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7MA P48730 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.253 15.019 BLAminus -130.46, 174.74 67.98, 83.71 -98.79, 25.27 291.86, 77.55 -66.69, -23.44 in-in in 8.095 Saltbr-in 3.072 HRD-in -82.95, -50.44 72.36, 6.41 in-in-out SNCiio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -118.7, 141.02 APE9-dihe-na 99.28, -143.16 APE8-dihe-in -115.41, 136.46 APE8-rot-out 60.38 APE67-dihe-in -67.86, -34.58 -60.29, -36.32 APE12-dist-in 12.669 APE11-dist-in 12.416 APE10-dist-in 7.086 APE9-dist-in 3.573 None None None XRAY 2.25 0.183 0.233 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7m Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7NA P48730 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.47 14.967 BLAminus -127.99, 178.2 71.62, 81.85 -100.07, 22.57 288.0, 76.27 -69.21, -18.63 in-in in 8.123 Saltbr-in 2.877 HRD-in -86.9, -49.86 74.3, 5.74 in-in-out SNCiio in-out ActLoopNT-in 2.838 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -123.0, 132.87 APE9-dihe-na 115.13, -139.46 APE8-dihe-in -121.63, 140.17 APE8-rot-out 70.58 APE67-dihe-in -63.32, -38.4 -59.59, -40.45 APE12-dist-in 13.162 APE11-dist-in 12.499 APE10-dist-in 7.236 APE9-dist-in 3.515 None None None XRAY 1.66 0.178 0.206 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7n Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7NB P48730 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.537 14.976 BLAminus -130.24, 179.04 70.68, 81.68 -101.75, 22.93 288.39, 79.24 -67.87, -18.61 in-in in 7.999 Saltbr-in 2.766 HRD-in -85.8, -48.58 73.18, 4.55 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.45, 133.01 APE9-dihe-na 113.72, -140.03 APE8-dihe-in -123.15, 141.08 APE8-rot-out 67.98 APE67-dihe-in -63.3, -37.53 -59.78, -40.69 APE12-dist-in 13.021 APE11-dist-in 12.267 APE10-dist-in 7.004 APE9-dist-in 3.484 None None None XRAY 1.66 0.178 0.206 B 301 289 0 0 0 0 [[9, 275]] 1.0 8d7n Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7OA P48730 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.438 14.957 BLAminus -128.77, 177.97 69.16, 82.85 -101.02, 21.65 287.23, 75.46 -66.58, -20.22 in-in in 8.108 Saltbr-in 2.795 HRD-in -85.14, -48.58 72.65, 5.41 in-in-out SNCiio in-out ActLoopNT-in 2.796 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -121.6, 136.66 APE9-dihe-na 109.53, -146.1 APE8-dihe-in -119.86, 137.24 APE8-rot-out 78.45 APE67-dihe-in -65.76, -36.62 -58.64, -37.48 APE12-dist-in 13.291 APE11-dist-in 12.22 APE10-dist-in 6.881 APE9-dist-in 3.465 None None None XRAY 1.65 0.174 0.209 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7o Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8D7PA P48730 2 290 415.0 No_ligand No_ligand Inactive DFGin 6.246 14.911 BLAminus -133.33, 173.52 68.46, 90.57 -100.72, 25.02 287.65, 91.78 -73.72, -17.9 in-in in 7.945 Saltbr-in 2.899 HRD-in -84.4, -53.17 75.27, 6.54 in-in-out SNCiio in-out ActLoopNT-in 3.007 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -114.48, 116.2 APE9-dihe-na -153.03, -158.4 APE8-dihe-in -103.86, 112.96 APE8-rot-in 293.06 APE67-dihe-in -63.47, -32.47 -54.33, -39.64 APE12-dist-out 14.516 APE11-dist-in 10.458 APE10-dist-in 7.706 APE9-dist-in 4.683 None None None XRAY 2.25 0.199 0.251 A 301 289 0 0 0 0 [[9, 275]] 1.0 8d7p Homo sapiens CK1_CSNK1D_HUMAN CK1 1.7e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 9B3SA P48730 2 415 415.0 No_ligand No_ligand Inactive DFGin 6.124 14.97 BLAminus -131.0, 174.44 67.26, 91.12 -104.02, 20.45 288.28, 101.1 -68.03, -27.02 in-out in 8.045 Saltbr-out 4.455 HRD-in -82.26, -51.13 69.79, 9.86 out-in-in SNCoii in-in ActLoopNT-in 2.955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -90.7, -46.44 APE9-dihe-na -89.21, -136.06 APE8-dihe-in -103.83, 124.46 APE8-rot-in 286.91 APE67-dihe-in -64.42, -32.2 -62.29, -32.3 APE12-dist-in 13.143 APE11-dist-in 11.532 APE10-dist-in 6.216 APE9-dist-in 3.994 None SEP411 SEP411 XRAY 2.4 0.199 0.247 A 320 300 0 0 0 0 [[9, 275]] 1.0 9b3s Homo sapiens CK1_CSNK1D_HUMAN CK1 2.1e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 9B3SB P48730 2 414 415.0 No_ligand No_ligand Inactive DFGin 6.205 14.552 BLAminus -130.17, 173.53 67.25, 93.15 -104.81, 23.02 293.67, 102.52 -66.31, -27.03 in-in in 7.907 Saltbr-in 2.623 HRD-in -79.37, -50.0 69.85, 7.95 in-in-out SNCiio in-out ActLoopNT-in 2.968 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -92.09, -48.23 APE9-dihe-na -89.27, -135.49 APE8-dihe-in -102.48, 124.6 APE8-rot-out 167.16 APE67-dihe-in -60.81, -30.73 -60.7, -35.64 APE12-dist-in 12.666 APE11-dist-in 11.783 APE10-dist-in 6.091 APE9-dist-in 4.096 None SEP411 SEP411 XRAY 2.4 0.199 0.247 B 320 299 0 0 0 0 [[9, 275]] 1.0 9b3s Homo sapiens CK1_CSNK1D_HUMAN CK1 2.1e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXPB P48730 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.336 14.439 BLAminus -135.69, 171.99 65.43, 95.83 -105.04, 23.46 292.76, 93.84 -72.82, -23.34 in-in in 8.233 Saltbr-in 3.244 HRD-in -82.3, -48.95 76.84, 1.52 in-in-out SNCiio in-out ActLoopNT-in 2.896 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -107.77, 123.24 APE9-dihe-na 110.47, 179.41 APE8-dihe-in -82.7, 140.76 APE8-rot-out 70.54 APE67-dihe-in -62.02, -36.03 -66.58, -29.77 APE12-dist-in 11.288 APE11-dist-in 11.956 APE10-dist-in 6.273 APE9-dist-in 3.65 K171E None None XRAY 2.35 0.201 0.243 B 294 293 0 0 0 0 [[9, 275]] 1.0 6pxp Homo sapiens CK1_CSNK1D_HUMAN CK1 4.4e-122 412.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXNA P48730 2 291 415.0 No_ligand No_ligand Inactive DFGin 5.856 14.978 BLAminus -132.46, 168.84 74.91, 102.22 -110.15, 18.1 290.1, 102.11 -68.22, -25.36 in-in in 8.187 Saltbr-in 2.754 HRD-in -80.27, -49.68 72.18, 6.82 in-in-out SNCiio in-out ActLoopNT-in 2.883 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -110.21, 152.93 APE9-dihe-na -78.09, -160.14 APE8-dihe-in -66.04, 140.6 APE8-rot-out 80.4 APE67-dihe-in -63.41, -31.35 -63.76, -40.1 APE12-dist-in 7.188 APE11-dist-out 6.662 APE10-dist-out 8.716 APE9-dist-in 3.676 R178C None None XRAY 1.551 0.178 0.205 A 415 290 0 0 0 0 [[9, 275]] 1.0 6pxn Homo sapiens CK1_CSNK1D_HUMAN CK1 5.7e-121 408.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6PXNB P48730 2 294 415.0 No_ligand No_ligand Inactive DFGin 5.617 14.9 BLAminus -135.34, 169.63 75.11, 102.01 -110.62, 18.83 289.28, 101.14 -67.9, -25.06 in-in in 8.057 Saltbr-in 2.786 HRD-in -82.97, -49.17 72.12, 6.3 in-in-out SNCiio in-out ActLoopNT-in 2.891 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -119.13, 132.73 APE9-dihe-na 91.36, -172.65 APE8-dihe-in -74.3, 140.34 APE8-rot-out 74.12 APE67-dihe-in -58.52, -41.43 -65.34, -38.29 APE12-dist-in 12.05 APE11-dist-in 11.667 APE10-dist-in 6.128 APE9-dist-in 3.619 R178C None None XRAY 1.551 0.178 0.205 B 415 290 3 0 0 0 [[9, 275]] 1.0 6pxn Homo sapiens CK1_CSNK1D_HUMAN CK1 5.7e-121 408.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8IZCA P48730 5 294 415.0 S93:60304 Type1 Inactive DFGin 5.755 15.352 BLAminus -130.99, 169.73 72.93, 98.69 -106.38, 19.42 290.01, 102.55 -60.76, -30.82 in-out in 8.492 Saltbr-out 3.695 HRD-in -80.11, -50.45 72.82, 8.45 out-in-in SNCoii in-in ActLoopNT-in 2.89 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.08, 148.91 APE9-dihe-na 104.57, -172.82 APE8-dihe-in -90.94, 118.12 APE8-rot-in 311.15 APE67-dihe-in -52.69, -38.41 -57.32, -35.93 APE12-dist-in 11.823 APE11-dist-in 11.984 APE10-dist-in 6.4 APE9-dist-in 4.116 None None None XRAY 1.45 0.192 0.207 A 291 287 3 0 0 0 [[9, 275]] 1.0 8izc Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 414.0 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5IH5A P48730 2 294 415.0 AUE:302 Type1 Inactive DFGin 5.915 15.467 BLAminus -135.97, 171.4 70.56, 96.84 -108.16, 25.64 287.22, 103.63 -71.2, -25.67 in-out in 8.485 Saltbr-out 3.943 HRD-in -85.95, -46.09 72.61, -4.04 out-in-in SNCoii in-in ActLoopNT-in 2.886 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.27, 140.91 APE9-dihe-na 91.08, -179.3 APE8-dihe-in -78.53, 130.37 APE8-rot-in 319.45 APE67-dihe-in -49.62, -42.09 -64.88, -37.16 APE12-dist-in 12.578 APE11-dist-in 11.639 APE10-dist-in 6.002 APE9-dist-in 3.876 None None None XRAY 2.25 0.241 0.26 A 294 287 6 0 0 0 [[9, 275]] 1.0 5ih5 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.5e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RCGA P48730 1 293 415.0 K0E:60303 Type1 Inactive DFGin 5.924 14.585 BLAminus -129.31, 167.16 80.86, 103.02 -107.22, 17.33 291.18, 104.04 -69.93, -23.99 in-in in 8.075 Saltbr-in 2.755 HRD-in -69.75, -46.72 69.28, 9.4 in-in-out SNCiio in-out ActLoopNT-in 2.863 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -118.81, 163.47 APE9-dihe-na -89.51, -143.43 APE8-dihe-in -74.96, 130.55 APE8-rot-out 75.54 APE67-dihe-in -56.1, -41.95 -57.15, -35.86 APE12-dist-in 7.157 APE11-dist-out 6.675 APE10-dist-out 8.321 APE9-dist-in 4.01 None None None XRAY 1.4 0.144 0.185 A 296 293 0 0 0 0 [[9, 275]] 1.0 6rcg Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QR9A P48730 3 294 415.0 EZQ:312 Type1 Inactive DFGin 5.763 15.243 BLAminus -136.84, 176.01 69.3, 97.09 -112.84, 23.4 285.61, 104.79 -72.19, -19.25 in-out in 8.482 Saltbr-out 3.622 HRD-in -85.43, -56.75 76.41, 12.88 out-in-in SNCoii in-in ActLoopNT-in 3.124 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.41, 110.89 APE9-dihe-na 139.78, -164.56 APE8-dihe-in -98.1, 116.37 APE8-rot-in 312.63 APE67-dihe-in -59.92, -37.62 -59.14, -34.82 APE12-dist-in 12.712 APE11-dist-in 12.127 APE10-dist-in 6.731 APE9-dist-in 4.191 None None None XRAY 2.3 0.254 0.305 A 296 289 3 0 0 0 [[9, 275]] 1.0 7qr9 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QR9C P48730 3 294 415.0 EZQ:303 Type1 Inactive DFGin 5.735 15.288 BLAminus -133.8, 175.29 70.48, 95.04 -111.33, 21.79 286.42, 101.5 -74.96, -14.27 in-out in 8.736 Saltbr-out 3.65 HRD-in -82.56, -56.81 79.28, 10.31 out-in-in SNCoii in-in ActLoopNT-in 3.13 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.84, 111.2 APE9-dihe-na 132.23, -160.89 APE8-dihe-in -99.97, 117.77 APE8-rot-in 314.9 APE67-dihe-in -61.01, -35.74 -61.99, -31.46 APE12-dist-in 11.17 APE11-dist-in 12.204 APE10-dist-in 6.441 APE9-dist-in 4.189 None None None XRAY 2.3 0.254 0.305 C 296 283 9 0 0 6 [[9, 275]] 1.0 7qr9 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7QR9D P48730 3 294 415.0 EZQ:303 Type1 Inactive DFGin 5.714 15.342 BLAminus -134.21, 175.57 68.31, 95.27 -111.54, 22.61 286.12, 100.88 -73.82, -15.96 in-out in 8.642 Saltbr-out 3.679 HRD-in -83.63, -56.81 80.2, 8.4 out-in-in SNCoii in-in ActLoopNT-in 3.127 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.08, 111.05 APE9-dihe-na 132.46, -153.49 APE8-dihe-in -99.73, 117.4 APE8-rot-in 313.33 APE67-dihe-in -61.32, -35.02 -60.84, -33.71 APE12-dist-in 12.721 APE11-dist-in 12.262 APE10-dist-in 6.556 APE9-dist-in 4.334 None None None XRAY 2.3 0.254 0.305 D 296 283 9 0 0 6 [[9, 275]] 1.0 7qr9 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4HGTA P48730 9 294 415.0 15G:301 Type1 Inactive DFGin 5.97 14.929 BLAminus -126.45, 174.59 58.3, 93.41 -99.95, 21.1 286.28, 98.6 -60.45, -14.72 in-in in 8.121 Saltbr-in 2.621 HRD-in -81.52, -43.64 66.43, 4.7 in-in-out SNCiio in-out ActLoopNT-in 2.82 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.93, 117.34 APE9-dihe-na 137.59, -158.78 APE8-dihe-in -111.58, 132.33 APE8-rot-out 134.04 APE67-dihe-in -51.49, -44.14 -54.45, -40.15 APE12-dist-in 13.563 APE11-dist-in 12.252 APE10-dist-in 6.704 APE9-dist-in 3.657 None None None XRAY 1.8 0.24 999.0 A 296 283 3 0 0 0 [[9, 275]] 1.0 4hgt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4HNFB P48730 5 294 415.0 16W:301 Type1 Inactive DFGin 6.555 15.866 BLAminus -134.11, -166.41 56.81, 78.35 -103.18, 26.32 281.92, 77.82 -64.45, -33.31 in-out in 8.639 Saltbr-out 4.622 HRD-in -79.26, -38.92 65.6, -2.59 out-in-in SNCoii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.72, 118.09 APE9-dihe-na 133.0, -140.96 APE8-dihe-in -114.37, 128.18 APE8-rot-in 299.03 APE67-dihe-in -47.74, -37.42 -57.39, -49.8 APE12-dist-in 12.605 APE11-dist-in 11.819 APE10-dist-in 6.019 APE9-dist-in 4.711 None None None XRAY 2.07 0.241 0.274 B 296 290 0 0 0 0 [[9, 275]] 1.0 4hnf Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8VXDA P48730 1 292 415.0 A1AD7:301 Type1 Inactive DFGin 6.825 15.091 BLAminus -131.19, -178.07 60.49, 73.82 -94.08, 18.87 291.45, 100.43 -70.24, -19.54 in-out in 8.178 Saltbr-out 4.036 HRD-in -79.2, -51.15 72.31, 8.44 out-in-out SNCoio in-out ActLoopNT-in 2.756 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -87.26, 134.18 APE9-dihe-na 97.04, -154.76 APE8-dihe-in -102.88, 131.3 APE8-rot-out 183.48 APE67-dihe-in -57.18, -40.09 -63.12, -35.04 APE12-dist-in 12.251 APE11-dist-in 12.074 APE10-dist-in 6.302 APE9-dist-in 4.009 None None None XRAY 2.47 0.267 0.295 A 300 285 7 0 0 0 [[9, 275]] 1.0 8vxd Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 8VXDB P48730 2 298 415.0 A1AD7:301 Type1 Inactive DFGin 6.034 14.743 BLAminus -131.39, -173.06 64.42, 76.08 -97.65, 19.56 289.92, 99.45 -69.34, -18.73 in-in in 8.266 Saltbr-in 2.794 HRD-in -78.49, -50.68 72.77, 8.1 in-in-out SNCiio in-out ActLoopNT-in 2.752 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnii APE10-dihe-na 999.0, -41.14 APE9-dihe-na -68.33, -154.01 APE8-dihe-in -101.8, 131.54 APE8-rot-out 206.9 APE67-dihe-in -58.04, -40.67 -62.8, -36.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 6.43 APE9-dist-in 4.032 None None None XRAY 2.47 0.267 0.295 B 300 291 6 0 0 4 [[9, 275]] 1.0 8vxd Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.8 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVA P48730 8 293 415.0 D5Q:301 Type1 Inactive DFGin 5.83 15.023 BLAminus -131.68, 168.75 74.06, 95.12 -107.7, 21.28 292.0, 96.98 -64.87, -25.36 in-in in 8.301 Saltbr-in 2.849 HRD-in -82.15, -48.81 72.48, 10.52 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.17, 102.31 APE9-dihe-na 125.3, -162.28 APE8-dihe-in -82.86, 141.1 APE8-rot-out 194.99 APE67-dihe-in -59.47, -41.03 -72.7, -36.43 APE12-dist-in 11.803 APE11-dist-in 11.631 APE10-dist-in 5.956 APE9-dist-in 4.126 None None None XRAY 2.154 0.173 0.192 A 314 286 0 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVC P48730 6 293 415.0 D5Q:301 Type1 Inactive DFGin 5.714 14.884 BLAminus -131.22, 168.19 73.22, 96.74 -107.26, 21.85 293.35, 97.6 -65.13, -25.75 in-in in 8.298 Saltbr-in 2.772 HRD-in -81.63, -48.95 72.04, 11.04 in-in-out SNCiio in-out ActLoopNT-in 2.871 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -115.55, 80.17 APE9-dihe-na 157.75, -163.71 APE8-dihe-in -83.2, 139.38 APE8-rot-out 188.1 APE67-dihe-in -59.64, -40.6 -72.53, -35.85 APE12-dist-in 12.044 APE11-dist-in 11.693 APE10-dist-in 6.111 APE9-dist-in 4.185 None None None XRAY 2.154 0.173 0.192 C 314 288 0 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5MQVF P48730 7 294 415.0 D5Q:301 Type1 Inactive DFGin 5.854 14.974 BLAminus -131.24, 169.41 73.24, 95.61 -107.61, 22.25 292.68, 97.01 -65.28, -25.58 in-in in 8.285 Saltbr-in 2.786 HRD-in -81.61, -48.18 72.2, 10.47 in-in-out SNCiio in-out ActLoopNT-in 2.924 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.6, 122.3 APE9-dihe-na 113.02, -165.98 APE8-dihe-in -85.3, 139.57 APE8-rot-out 192.65 APE67-dihe-in -59.21, -40.66 -71.37, -34.49 APE12-dist-in 12.193 APE11-dist-in 11.77 APE10-dist-in 6.163 APE9-dist-in 3.821 None None None XRAY 2.154 0.173 0.192 F 314 286 2 0 0 0 [[9, 275]] 1.0 5mqv Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6GZMA P48730 5 295 415.0 LCI:1004 Type1 Inactive DFGin 6.092 14.898 BLAminus -124.32, 164.33 79.67, 96.2 -103.0, 21.73 291.46, 97.37 -70.61, -17.22 in-in in 7.992 Saltbr-in 3.067 HRD-in -80.76, -48.3 70.22, 11.09 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -102.57, -30.36 APE9-dihe-na -78.6, -147.37 APE8-dihe-in -125.32, 169.57 APE8-rot-out 191.56 APE67-dihe-in -53.28, -42.94 -88.52, -29.67 APE12-dist-in 13.557 APE11-dist-in 12.32 APE10-dist-in 6.969 APE9-dist-in 4.557 R13N None None XRAY 1.59 0.192 0.25 A 295 291 0 0 0 0 [[9, 275]] 1.0 6gzm Homo sapiens CK1_CSNK1D_HUMAN CK1 3.8e-122 412.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBKD P48730 3 293 415.0 1QG:401 Type1 Inactive DFGin 5.881 14.926 BLAminus -131.43, 175.27 63.3, 98.83 -106.81, 21.53 289.62, 102.69 -62.31, -31.85 in-in in 8.355 Saltbr-in 2.919 HRD-in -74.75, -48.67 75.76, -0.04 in-in-out SNCiio in-out ActLoopNT-in 2.915 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -103.02, 130.08 APE9-dihe-na 105.3, -173.89 APE8-dihe-in -83.33, 130.0 APE8-rot-out 40.11 APE67-dihe-in -55.34, -39.95 -56.81, -38.76 APE12-dist-in 12.407 APE11-dist-in 12.083 APE10-dist-in 6.378 APE9-dist-in 3.679 None None None XRAY 2.1 0.193 0.225 D 331 281 10 0 0 0 [[9, 275]] 1.0 4kbk Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 6RU6B P48730 3 294 415.0 ACP:60301 ATPlike None DFGin 6.59 15.156 BLAminus -129.63, 177.25 73.9, 71.28 -92.31, 21.27 283.76, 74.29 -58.84, -31.38 in-in in 7.818 Saltbr-in 2.796 HRD-in -76.32, -55.32 74.02, 14.82 in-in-none SNCiin in-none ActLoopNT-in 2.86 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.17 APE8-dihe-in -104.51, 127.76 APE8-rot-in 311.88 APE67-dihe-in -57.59, -35.09 -58.93, -44.33 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.941 None None None XRAY 2.05 0.213 0.257 B 296 278 14 0 0 8 [[9, 275]] 1.0 6ru6 Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 3UYTD P48730 4 294 415.0 0CK:295 Type1 None DFGin 6.058 14.902 BLAminus -125.11, 171.89 69.6, 107.56 -115.59, 22.0 279.81, 112.96 -71.13, -36.34 in-in in 8.444 Saltbr-in 3.03 HRD-in -87.06, -44.31 72.64, -9.74 in-in-none SNCiin in-none ActLoopNT-in 2.996 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, 157.15 APE9-dihe-na 110.54, 179.72 APE8-dihe-in -77.04, 125.8 APE8-rot-in 336.84 APE67-dihe-in -54.65, -24.61 -55.67, -34.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 6.132 APE9-dist-in 4.59 None None None XRAY 2.0 0.244 0.264 D 296 268 23 0 0 16 [[9, 275]] 1.0 3uyt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 5OKTB P48730 4 294 415.0 9XK:301 Type1 None DFGin 6.127 14.635 BLAminus -133.48, 170.79 70.83, 88.65 -98.93, 18.4 294.6, 95.75 -62.62, -31.39 in-in in 7.966 Saltbr-in 2.832 HRD-in -78.04, -48.78 74.52, -0.37 in-in-none SNCiin in-none ActLoopNT-in 2.878 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -70.45 APE9-dihe-na -87.34, -162.07 APE8-dihe-in -74.91, 135.72 APE8-rot-in 311.98 APE67-dihe-in -57.97, -40.98 -67.96, -35.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.351 APE9-dist-in 3.835 None TPO220 TPO220 XRAY 2.13 0.194 0.221 B 314 282 9 0 0 9 [[9, 275]] 1.0 5okt Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 7NZYB P48730 2 294 415.0 UX2:301 Type1 None DFGin 6.558 14.882 BLAminus -133.2, 168.2 69.93, 96.11 -104.78, 25.32 292.5, 81.62 -64.88, -24.78 in-in in 8.136 Saltbr-in 2.965 HRD-in -79.22, -50.76 76.11, 7.31 in-in-none SNCiin in-none ActLoopNT-in 2.89 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_niii APE10-dihe-na -70.52, -73.6 APE9-dihe-na -68.02, -150.38 APE8-dihe-in -91.32, 139.07 APE8-rot-in 311.34 APE67-dihe-in -57.14, -39.91 -68.37, -36.29 APE12-dist-none 999.0 APE11-dist-in 11.813 APE10-dist-in 6.872 APE9-dist-in 3.731 None TPO220 TPO220 XRAY 1.85 0.205 0.229 B 314 286 7 0 0 7 [[9, 275]] 1.0 7nzy Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KB8A P48730 3 293 415.0 1QN:401 Type1 None DFGin 5.98 14.795 BLAminus -126.76, 172.83 67.65, 98.79 -108.65, 18.05 291.14, 100.67 -60.78, -33.86 in-in in 8.264 Saltbr-in 2.885 HRD-in -74.47, -48.24 76.4, -6.59 in-in-none SNCiin in-none ActLoopNT-in 2.926 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -159.46 APE8-dihe-in -103.07, 128.56 APE8-rot-in 304.05 APE67-dihe-in -56.21, -39.45 -54.48, -41.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.597 None None None XRAY 1.95 0.207 0.232 A 331 265 26 0 0 18 [[9, 275]] 1.0 4kb8 Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_HUMAN 4KBAA P48730 3 293 415.0 1QM:401 Type1 None DFGin 5.942 14.713 BLAminus -128.03, 172.49 65.02, 105.13 -114.85, 19.06 291.3, 105.5 -62.25, -33.76 in-in in 8.12 Saltbr-in 2.814 HRD-in -73.17, -51.42 78.43, -6.31 in-in-none SNCiin in-none ActLoopNT-in 2.918 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -160.81 APE8-dihe-in -100.61, 126.43 APE8-rot-in 305.06 APE67-dihe-in -59.74, -39.86 -55.88, -36.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 3.561 None None None XRAY 1.98 0.21 0.237 A 331 263 28 0 0 18 [[9, 275]] 1.0 4kba Homo sapiens CK1_CSNK1D_HUMAN CK1 2.3e-122 413.4 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 4JJRB Q9DC28 1 293 415.0 No_ligand No_ligand Active DFGin 6.077 15.295 BLAminus -129.34, 175.38 66.94, 91.98 -104.35, 22.53 288.17, 92.64 -65.0, -22.66 in-in in 8.14 Saltbr-in 2.41 HRD-in -75.39, -46.68 69.44, 7.28 in-in-in SNCiii in-in ActLoopNT-in 2.814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.06, -53.6 APE9-dihe-na -97.38, -132.51 APE8-dihe-in -90.16, 129.71 APE8-rot-in 300.8 APE67-dihe-in -57.12, -34.8 -63.27, -38.06 APE12-dist-in 12.477 APE11-dist-in 11.805 APE10-dist-in 5.954 APE9-dist-in 4.377 None None None XRAY 2.408 0.211 0.237 B 299 283 10 0 0 0 [[9, 275]] 1.0 4jjr Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 5X17A Q9DC28 3 292 415.0 ADP:307 Type1.5_Back Active DFGin 5.885 15.017 BLAminus -136.76, 176.51 70.17, 78.89 -96.78, 24.57 288.71, 93.09 -76.8, -15.99 in-in in 8.102 Saltbr-in 3.148 HRD-in -73.34, -55.18 81.19, 1.41 in-in-in SNCiii in-in ActLoopNT-in 2.824 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.47, -59.72 APE9-dihe-na -86.86, -154.47 APE8-dihe-in -76.87, 120.04 APE8-rot-in 308.55 APE67-dihe-in -51.63, -37.36 -55.73, -38.13 APE12-dist-in 10.457 APE11-dist-in 12.417 APE10-dist-in 6.378 APE9-dist-in 3.807 None None None XRAY 2.0 0.19 0.242 A 296 290 0 0 0 0 [[9, 275]] 1.0 5x17 Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 5X17B Q9DC28 4 292 415.0 ADP:306 Type1.5_Back Active DFGin 6.333 14.989 BLAminus -121.28, -179.96 69.25, 82.44 -101.59, 21.98 290.59, 89.01 -77.86, -17.5 in-in in 8.042 Saltbr-in 3.107 HRD-in -90.58, -48.35 72.79, 12.65 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.44, 137.77 APE9-dihe-na 91.26, -171.32 APE8-dihe-in -91.08, 137.89 APE8-rot-in 301.79 APE67-dihe-in -58.2, -31.0 -69.62, -39.78 APE12-dist-in 12.297 APE11-dist-in 11.987 APE10-dist-in 6.492 APE9-dist-in 3.373 None None None XRAY 2.0 0.19 0.242 B 296 289 0 0 0 0 [[9, 275]] 1.0 5x17 Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 4JJRA Q9DC28 3 299 415.0 No_ligand No_ligand Inactive DFGin 5.878 15.144 BLAminus -129.36, 174.89 66.5, 91.83 -103.88, 22.59 287.99, 93.46 -65.36, -22.96 in-in in 8.303 Saltbr-in 2.725 HRD-in -74.57, -46.2 69.39, 8.73 in-in-out SNCiio in-out ActLoopNT-in 2.78 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 141.35 APE9-dihe-na -98.48, -131.43 APE8-dihe-in -89.19, 130.03 APE8-rot-in 299.84 APE67-dihe-in -56.3, -35.51 -63.95, -38.59 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.575 APE9-dist-in 4.359 None None None XRAY 2.408 0.211 0.237 A 299 284 13 0 0 3 [[9, 275]] 1.0 4jjr Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKJB Q06486 1 293 415.0 WO4:60400,WO4:60401,WO4:60402 Allosteric,Allosteric,Allosteric Active DFGin 5.82 14.812 BLAminus -135.23, 175.64 62.79, 89.89 -101.72, 20.71 292.58, 105.85 -61.23, -35.52 in-in in 7.987 Saltbr-in 2.632 HRD-in -64.7, -45.81 62.27, 14.47 in-in-in SNCiii in-in ActLoopNT-in 2.79 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.59, 105.9 APE9-dihe-na 121.16, -172.89 APE8-dihe-in -69.55, 120.27 APE8-rot-in 309.55 APE67-dihe-in -64.97, -29.86 -64.73, -22.79 APE12-dist-in 12.422 APE11-dist-in 12.377 APE10-dist-in 6.88 APE9-dist-in 4.023 None None None XRAY 2.46 0.192 0.271 B 317 293 0 0 0 0 [[9, 275]] 1.0 1ckj Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKIB Q06486 1 293 415.0 No_ligand No_ligand Active DFGin 5.992 14.97 BLAminus -132.62, 174.91 66.91, 95.78 -106.14, 21.84 287.73, 105.07 -54.89, -41.9 in-in in 8.297 Saltbr-in 2.806 HRD-in -61.88, -50.0 67.09, 16.48 in-in-in SNCiii in-in ActLoopNT-in 2.768 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.37, 91.78 APE9-dihe-na 143.61, -166.77 APE8-dihe-in -76.48, 132.92 APE8-rot-in 304.57 APE67-dihe-in -55.77, -38.47 -65.81, -39.41 APE12-dist-in 12.049 APE11-dist-in 12.271 APE10-dist-in 6.761 APE9-dist-in 4.017 None None None XRAY 2.3 0.193 0.279 B 317 286 7 0 0 0 [[9, 275]] 1.0 1cki Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKJA Q06486 1 296 415.0 WO4:60400,WO4:60401 Allosteric,Allosteric Inactive DFGin 6.07 14.996 BLAminus -122.54, 172.34 71.65, 86.6 -100.84, 38.96 294.19, 108.89 -72.88, -43.23 in-in in 8.326 Saltbr-in 3.039 HRD-in -74.31, -43.6 72.86, -5.4 in-in-out SNCiio in-out ActLoopNT-in 2.769 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -99.59, 162.76 APE9-dihe-na -103.27, -153.2 APE8-dihe-in -61.86, 118.63 APE8-rot-in 312.76 APE67-dihe-in -66.68, -37.45 -60.66, -23.75 APE12-dist-in 7.865 APE11-dist-out 5.625 APE10-dist-out 8.946 APE9-dist-in 4.4 None None None XRAY 2.46 0.192 0.271 A 317 296 0 0 0 0 [[9, 275]] 1.0 1ckj Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKIA Q06486 1 299 415.0 No_ligand No_ligand Inactive DFGin 6.089 14.864 BLAminus -121.7, 172.4 70.78, 93.56 -104.52, 33.01 293.78, 105.3 -65.34, -45.99 in-in in 8.354 Saltbr-in 2.892 HRD-in -63.31, -46.72 73.14, 0.04 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -98.23, 164.29 APE9-dihe-na -105.11, -156.18 APE8-dihe-in -61.17, 137.73 APE8-rot-in 302.12 APE67-dihe-in -64.83, -39.08 -77.57, -22.94 APE12-dist-in 8.019 APE11-dist-out 5.898 APE10-dist-out 9.057 APE9-dist-in 4.202 None None None XRAY 2.3 0.193 0.279 A 317 292 7 0 0 0 [[9, 275]] 1.0 1cki Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta

CK1_CSNK1D (Casein kinase I isoform delta)

Total number of chains: 8
Active chains: 5
Family: CK1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% 5X17A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KC1D_MOUSE 4JJRB Q9DC28 1 293 415.0 No_ligand No_ligand Active DFGin 6.077 15.295 BLAminus -129.34, 175.38 66.94, 91.98 -104.35, 22.53 288.17, 92.64 -65.0, -22.66 in-in in 8.14 Saltbr-in 2.41 HRD-in -75.39, -46.68 69.44, 7.28 in-in-in SNCiii in-in ActLoopNT-in 2.814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -81.06, -53.6 APE9-dihe-na -97.38, -132.51 APE8-dihe-in -90.16, 129.71 APE8-rot-in 300.8 APE67-dihe-in -57.12, -34.8 -63.27, -38.06 APE12-dist-in 12.477 APE11-dist-in 11.805 APE10-dist-in 5.954 APE9-dist-in 4.377 None None None XRAY 2.408 0.211 0.237 B 299 283 10 0 0 0 [[9, 275]] 1.0 4jjr Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 5X17A Q9DC28 3 292 415.0 ADP:307 Type1.5_Back Active DFGin 5.885 15.017 BLAminus -136.76, 176.51 70.17, 78.89 -96.78, 24.57 288.71, 93.09 -76.8, -15.99 in-in in 8.102 Saltbr-in 3.148 HRD-in -73.34, -55.18 81.19, 1.41 in-in-in SNCiii in-in ActLoopNT-in 2.824 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.47, -59.72 APE9-dihe-na -86.86, -154.47 APE8-dihe-in -76.87, 120.04 APE8-rot-in 308.55 APE67-dihe-in -51.63, -37.36 -55.73, -38.13 APE12-dist-in 10.457 APE11-dist-in 12.417 APE10-dist-in 6.378 APE9-dist-in 3.807 None None None XRAY 2.0 0.19 0.242 A 296 290 0 0 0 0 [[9, 275]] 1.0 5x17 Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 5X17B Q9DC28 4 292 415.0 ADP:306 Type1.5_Back Active DFGin 6.333 14.989 BLAminus -121.28, -179.96 69.25, 82.44 -101.59, 21.98 290.59, 89.01 -77.86, -17.5 in-in in 8.042 Saltbr-in 3.107 HRD-in -90.58, -48.35 72.79, 12.65 in-in-in SNCiii in-in ActLoopNT-in 2.76 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.44, 137.77 APE9-dihe-na 91.26, -171.32 APE8-dihe-in -91.08, 137.89 APE8-rot-in 301.79 APE67-dihe-in -58.2, -31.0 -69.62, -39.78 APE12-dist-in 12.297 APE11-dist-in 11.987 APE10-dist-in 6.492 APE9-dist-in 3.373 None None None XRAY 2.0 0.19 0.242 B 296 289 0 0 0 0 [[9, 275]] 1.0 5x17 Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_MOUSE 4JJRA Q9DC28 3 299 415.0 No_ligand No_ligand Inactive DFGin 5.878 15.144 BLAminus -129.36, 174.89 66.5, 91.83 -103.88, 22.59 287.99, 93.46 -65.36, -22.96 in-in in 8.303 Saltbr-in 2.725 HRD-in -74.57, -46.2 69.39, 8.73 in-in-out SNCiio in-out ActLoopNT-in 2.78 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 141.35 APE9-dihe-na -98.48, -131.43 APE8-dihe-in -89.19, 130.03 APE8-rot-in 299.84 APE67-dihe-in -56.3, -35.51 -63.95, -38.59 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.575 APE9-dist-in 4.359 None None None XRAY 2.408 0.211 0.237 A 299 284 13 0 0 3 [[9, 275]] 1.0 4jjr Mus musculus CK1_CSNK1D_MOUSE CK1 1.6e-122 413.9 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKJB Q06486 1 293 415.0 WO4:60400,WO4:60401,WO4:60402 Allosteric,Allosteric,Allosteric Active DFGin 5.82 14.812 BLAminus -135.23, 175.64 62.79, 89.89 -101.72, 20.71 292.58, 105.85 -61.23, -35.52 in-in in 7.987 Saltbr-in 2.632 HRD-in -64.7, -45.81 62.27, 14.47 in-in-in SNCiii in-in ActLoopNT-in 2.79 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.59, 105.9 APE9-dihe-na 121.16, -172.89 APE8-dihe-in -69.55, 120.27 APE8-rot-in 309.55 APE67-dihe-in -64.97, -29.86 -64.73, -22.79 APE12-dist-in 12.422 APE11-dist-in 12.377 APE10-dist-in 6.88 APE9-dist-in 4.023 None None None XRAY 2.46 0.192 0.271 B 317 293 0 0 0 0 [[9, 275]] 1.0 1ckj Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKIB Q06486 1 293 415.0 No_ligand No_ligand Active DFGin 5.992 14.97 BLAminus -132.62, 174.91 66.91, 95.78 -106.14, 21.84 287.73, 105.07 -54.89, -41.9 in-in in 8.297 Saltbr-in 2.806 HRD-in -61.88, -50.0 67.09, 16.48 in-in-in SNCiii in-in ActLoopNT-in 2.768 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.37, 91.78 APE9-dihe-na 143.61, -166.77 APE8-dihe-in -76.48, 132.92 APE8-rot-in 304.57 APE67-dihe-in -55.77, -38.47 -65.81, -39.41 APE12-dist-in 12.049 APE11-dist-in 12.271 APE10-dist-in 6.761 APE9-dist-in 4.017 None None None XRAY 2.3 0.193 0.279 B 317 286 7 0 0 0 [[9, 275]] 1.0 1cki Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKJA Q06486 1 296 415.0 WO4:60400,WO4:60401 Allosteric,Allosteric Inactive DFGin 6.07 14.996 BLAminus -122.54, 172.34 71.65, 86.6 -100.84, 38.96 294.19, 108.89 -72.88, -43.23 in-in in 8.326 Saltbr-in 3.039 HRD-in -74.31, -43.6 72.86, -5.4 in-in-out SNCiio in-out ActLoopNT-in 2.769 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -99.59, 162.76 APE9-dihe-na -103.27, -153.2 APE8-dihe-in -61.86, 118.63 APE8-rot-in 312.76 APE67-dihe-in -66.68, -37.45 -60.66, -23.75 APE12-dist-in 7.865 APE11-dist-out 5.625 APE10-dist-out 8.946 APE9-dist-in 4.4 None None None XRAY 2.46 0.192 0.271 A 317 296 0 0 0 0 [[9, 275]] 1.0 1ckj Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
KC1D_RAT 1CKIA Q06486 1 299 415.0 No_ligand No_ligand Inactive DFGin 6.089 14.864 BLAminus -121.7, 172.4 70.78, 93.56 -104.52, 33.01 293.78, 105.3 -65.34, -45.99 in-in in 8.354 Saltbr-in 2.892 HRD-in -63.31, -46.72 73.14, 0.04 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -98.23, 164.29 APE9-dihe-na -105.11, -156.18 APE8-dihe-in -61.17, 137.73 APE8-rot-in 302.12 APE67-dihe-in -64.83, -39.08 -77.57, -22.94 APE12-dist-in 8.019 APE11-dist-out 5.898 APE10-dist-out 9.057 APE9-dist-in 4.202 None None None XRAY 2.3 0.193 0.279 A 317 292 7 0 0 0 [[9, 275]] 1.0 1cki Rattus norvegicus CK1_CSNK1D_RAT CK1 2e-122 413.6 1 262 262 148 149 150 152 154 38 52 56 125 127 126 128 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta