CMGC_CDKL5 (Cyclin-dependent kinase-like 5)

Total number of chains: 5
Active chains: 2
Uniprot: CDKL5_HUMAN
Kinase Domain Residues: 13 - 297
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-O76039-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O76039-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 305 0 None None Cyclin-dependent kinase-like 5
AF-O76039-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 305 0 None None Cyclin-dependent kinase-like 5
4BGQA 2.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aanni APEdist_nnnn 38R Type1 9 - 302 0 None T169D,Y171E Cyclin-dependent kinase-like 5
8CIEA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo US0 Type1 13 - 303 0 None None Cyclin-dependent kinase-like 5
9EPUA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo A1H6P Type1 12 - 303 0 None None Cyclin-dependent kinase-like 5

CMGC_CDKL5 (Cyclin-dependent kinase-like 5)

Total number of chains: 5
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% AF-O76039-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDKL5_HUMAN AF-O76039-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 305 0 None None Cyclin-dependent kinase-like 5 Homo sapiens
CDKL5_HUMAN AF-O76039-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 305 0 None None Cyclin-dependent kinase-like 5 Homo sapiens
CDKL5_HUMAN 4BGQA 2.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aanni APEdist_nnnn 38R Type1 9 - 302 0 None T169D,Y171E Cyclin-dependent kinase-like 5 Homo sapiens
CDKL5_HUMAN 8CIEA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo US0 Type1 13 - 303 0 None None Cyclin-dependent kinase-like 5 Homo sapiens
CDKL5_HUMAN 9EPUA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo A1H6P Type1 12 - 303 0 None None Cyclin-dependent kinase-like 5 Homo sapiens

CMGC_CDKL5 (Cyclin-dependent kinase-like 5)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism