CMGC_CDKL4 (Cyclin-dependent kinase-like 4)

Total number of chains: 2
Active chains: 2
Uniprot: CDKL4_HUMAN
Kinase Domain Residues: 4 - 286
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q5MAI5-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDKL4 AF-Q5MAI5-K1A Q5MAI5 1 294 379.0 No_ligand No_ligand Active DFGin 6.7113 15.3835 BLAminus -133.29, 177.44 65.78, 59.97 -75.37, 19.35 279.55, 69.15 -61.71, -35.43 in-in in 8.7418 Saltbr-in 2.7679 HRD-in -81.63, -45.22 62.6, 19.49 in-in-in SNCiii in-in ActLoopNT-in 2.8595 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.68, 171.96 APE9-dihe-na 58.57, 140.68 APE8-dihe-in -64.03, 135.44 APE8-rot-in 301.05 APE67-dihe-in -65.26, -22.24 -45.42, -45.39 APE12-dist-in 12.8283 APE11-dist-in 10.8029 APE10-dist-in 6.2928 APE9-dist-in 3.2075 None None None AF2 -1.0 1.0 1.0 A 294.0 294.0 0 27 27 0 [[4, 286]] 1.0 AF-Q5MAI5-K1 CMGC_CDKL4_HUMAN CMGC 9.1e-81 277.3 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 183 170 165 164 163 162 161 160 159 81 Cyclin-dependent kinase-like 4
CDKL4 AF-Q5MAI5-K3A Q5MAI5 1 294 379.0 No_ligand No_ligand Active DFGin 6.5896 15.4108 BLAminus -127.78, -178.11 66.08, 48.32 -65.6, 11.62 278.82, 78.8 -63.17, -31.0 in-in in 8.4008 Saltbr-in 2.7771 HRD-in -82.51, -45.23 62.5, 13.57 in-in-in SNCiii in-in ActLoopNT-in 2.8513 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.51, 172.59 APE9-dihe-na 58.39, 146.32 APE8-dihe-in -67.39, 134.97 APE8-rot-in 300.33 APE67-dihe-in -63.57, -21.81 -49.99, -42.28 APE12-dist-in 12.7119 APE11-dist-in 10.618 APE10-dist-in 6.2382 APE9-dist-in 3.2071 None None None AF2 -1.0 1.0 1.0 A 294.0 294.0 0 27 27 0 [[4, 286]] 1.0 AF-Q5MAI5-K3 CMGC_CDKL4_HUMAN CMGC 9.1e-81 277.3 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 183 170 165 164 163 162 161 160 159 81 Cyclin-dependent kinase-like 4

CMGC_CDKL4 (Cyclin-dependent kinase-like 4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q5MAI5-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDKL4 CDKL4_HUMAN AF-Q5MAI5-K1A Q5MAI5 1 294 379.0 No_ligand No_ligand Active DFGin 6.7113 15.3835 BLAminus -133.29, 177.44 65.78, 59.97 -75.37, 19.35 279.55, 69.15 -61.71, -35.43 in-in in 8.7418 Saltbr-in 2.7679 HRD-in -81.63, -45.22 62.6, 19.49 in-in-in SNCiii in-in ActLoopNT-in 2.8595 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.68, 171.96 APE9-dihe-na 58.57, 140.68 APE8-dihe-in -64.03, 135.44 APE8-rot-in 301.05 APE67-dihe-in -65.26, -22.24 -45.42, -45.39 APE12-dist-in 12.8283 APE11-dist-in 10.8029 APE10-dist-in 6.2928 APE9-dist-in 3.2075 None None None AF2 -1.0 1.0 1.0 A 294.0 294.0 0 27 27 0 [[4, 286]] 1.0 AF-Q5MAI5-K1 Homo sapiens CMGC_CDKL4_HUMAN CMGC 9.1e-81 277.3 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 183 170 165 164 163 162 161 160 159 81 Cyclin-dependent kinase-like 4
CDKL4 CDKL4_HUMAN AF-Q5MAI5-K3A Q5MAI5 1 294 379.0 No_ligand No_ligand Active DFGin 6.5896 15.4108 BLAminus -127.78, -178.11 66.08, 48.32 -65.6, 11.62 278.82, 78.8 -63.17, -31.0 in-in in 8.4008 Saltbr-in 2.7771 HRD-in -82.51, -45.23 62.5, 13.57 in-in-in SNCiii in-in ActLoopNT-in 2.8513 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.51, 172.59 APE9-dihe-na 58.39, 146.32 APE8-dihe-in -67.39, 134.97 APE8-rot-in 300.33 APE67-dihe-in -63.57, -21.81 -49.99, -42.28 APE12-dist-in 12.7119 APE11-dist-in 10.618 APE10-dist-in 6.2382 APE9-dist-in 3.2071 None None None AF2 -1.0 1.0 1.0 A 294.0 294.0 0 27 27 0 [[4, 286]] 1.0 AF-Q5MAI5-K3 Homo sapiens CMGC_CDKL4_HUMAN CMGC 9.1e-81 277.3 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 183 170 165 164 163 162 161 160 159 81 Cyclin-dependent kinase-like 4

CMGC_CDKL4 (Cyclin-dependent kinase-like 4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name