CMGC_CDK18 (Cyclin-dependent kinase 18)

Total number of chains: 2
Active chains: 2
Uniprot: CDK18_HUMAN
Kinase Domain Residues: 144 - 425
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q07002-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDK18 AF-Q07002-K1A Q07002 136 433 474.0 No_ligand No_ligand Active DFGin 6.9539 15.2114 BLAminus -128.35, 176.98 51.78, 72.16 -84.2, 17.75 283.05, 69.4 -59.73, -33.84 in-in in 8.7485 Saltbr-in 2.7795 HRD-in -76.19, -46.87 61.05, 17.96 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.28, 161.96 APE9-dihe-na 62.68, 129.51 APE8-dihe-in -54.83, 137.5 APE8-rot-in 300.21 APE67-dihe-in -64.49, -14.74 -44.5, -49.87 APE12-dist-in 13.1821 APE11-dist-in 10.6011 APE10-dist-in 6.8168 APE9-dist-in 3.2809 None None None AF2 -1.0 1.0 1.0 A 298.0 298.0 0 28 28 0 [[144, 425]] 1.0 AF-Q07002-K1 CMGC_CDK18_HUMAN CMGC 1.6e-81 279.9 1.0 301.0 301.0 282 283 284 286 288 173 190 194 262 264 263 265.0 323 310 305 304 303 302 301 300 299 220 Cyclin-dependent kinase 18
CDK18 AF-Q07002-K3A Q07002 136 433 474.0 No_ligand No_ligand Active DFGin 6.84 14.9984 BLAminus -136.69, 175.89 56.15, 65.6 -80.54, 15.18 283.1, 72.29 -59.09, -33.28 in-in in 8.7825 Saltbr-in 2.7856 HRD-in -77.22, -50.56 64.04, 14.42 in-in-in SNCiii in-in ActLoopNT-in 2.8778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.12, 155.39 APE9-dihe-na 63.73, 138.07 APE8-dihe-in -56.62, 136.2 APE8-rot-in 299.19 APE67-dihe-in -63.74, -12.49 -43.92, -53.23 APE12-dist-in 13.6954 APE11-dist-in 11.1019 APE10-dist-in 7.3618 APE9-dist-in 3.3554 None None None AF2 -1.0 1.0 1.0 A 298.0 298.0 0 28 28 0 [[144, 425]] 1.0 AF-Q07002-K3 CMGC_CDK18_HUMAN CMGC 1.6e-81 279.9 1.0 301.0 301.0 282 283 284 286 288 173 190 194 262 264 263 265.0 323 310 305 304 303 302 301 300 299 220 Cyclin-dependent kinase 18

CMGC_CDK18 (Cyclin-dependent kinase 18)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q07002-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDK18 CDK18_HUMAN AF-Q07002-K1A Q07002 136 433 474.0 No_ligand No_ligand Active DFGin 6.9539 15.2114 BLAminus -128.35, 176.98 51.78, 72.16 -84.2, 17.75 283.05, 69.4 -59.73, -33.84 in-in in 8.7485 Saltbr-in 2.7795 HRD-in -76.19, -46.87 61.05, 17.96 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.28, 161.96 APE9-dihe-na 62.68, 129.51 APE8-dihe-in -54.83, 137.5 APE8-rot-in 300.21 APE67-dihe-in -64.49, -14.74 -44.5, -49.87 APE12-dist-in 13.1821 APE11-dist-in 10.6011 APE10-dist-in 6.8168 APE9-dist-in 3.2809 None None None AF2 -1.0 1.0 1.0 A 298.0 298.0 0 28 28 0 [[144, 425]] 1.0 AF-Q07002-K1 Homo sapiens CMGC_CDK18_HUMAN CMGC 1.6e-81 279.9 1.0 301.0 301.0 282 283 284 286 288 173 190 194 262 264 263 265.0 323 310 305 304 303 302 301 300 299 220 Cyclin-dependent kinase 18
CDK18 CDK18_HUMAN AF-Q07002-K3A Q07002 136 433 474.0 No_ligand No_ligand Active DFGin 6.84 14.9984 BLAminus -136.69, 175.89 56.15, 65.6 -80.54, 15.18 283.1, 72.29 -59.09, -33.28 in-in in 8.7825 Saltbr-in 2.7856 HRD-in -77.22, -50.56 64.04, 14.42 in-in-in SNCiii in-in ActLoopNT-in 2.8778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.12, 155.39 APE9-dihe-na 63.73, 138.07 APE8-dihe-in -56.62, 136.2 APE8-rot-in 299.19 APE67-dihe-in -63.74, -12.49 -43.92, -53.23 APE12-dist-in 13.6954 APE11-dist-in 11.1019 APE10-dist-in 7.3618 APE9-dist-in 3.3554 None None None AF2 -1.0 1.0 1.0 A 298.0 298.0 0 28 28 0 [[144, 425]] 1.0 AF-Q07002-K3 Homo sapiens CMGC_CDK18_HUMAN CMGC 1.6e-81 279.9 1.0 301.0 301.0 282 283 284 286 288 173 190 194 262 264 263 265.0 323 310 305 304 303 302 301 300 299 220 Cyclin-dependent kinase 18

CMGC_CDK18 (Cyclin-dependent kinase 18)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name