CMGC_CDK10 (Cyclin-dependent kinase 10)

Total number of chains: 2
Active chains: 2
Uniprot: CDK10_HUMAN
Kinase Domain Residues: 39 - 323
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15131-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDK10 AF-Q15131-K1A Q15131 31 331 360.0 No_ligand No_ligand Active DFGin 6.8191 14.585 BLAminus -134.17, 178.47 59.03, 71.87 -85.25, 14.73 282.8, 72.74 -59.17, -29.64 in-in in 8.9422 Saltbr-in 2.7319 HRD-in -72.11, -46.66 62.07, 11.62 in-in-in SNCiii in-in ActLoopNT-in 2.9529 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.42, 169.37 APE9-dihe-na 63.7, 130.69 APE8-dihe-in -54.65, 137.66 APE8-rot-in 299.7 APE67-dihe-in -67.0, -22.85 -48.01, -43.94 APE12-dist-in 12.9959 APE11-dist-in 11.1815 APE10-dist-in 6.5459 APE9-dist-in 3.2391 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 28 28 0 [[39, 323]] 1.0 AF-Q15131-K1 CMGC_CDK10_HUMAN CMGC 1.2e-77 267.1 1.0 301.0 301.0 180 181 182 184 186 68 86 90 160 162 161 163.0 221 208 203 202 201 200 199 198 197 118 Cyclin-dependent kinase 10
CDK10 AF-Q15131-K3A Q15131 31 331 360.0 No_ligand No_ligand Active DFGin 6.6963 14.7927 BLAminus -131.02, -178.74 61.85, 65.75 -79.68, 11.21 285.29, 77.94 -59.95, -29.89 in-in in 8.8551 Saltbr-in 2.7096 HRD-in -78.08, -43.62 64.02, 9.06 in-in-in SNCiii in-in ActLoopNT-in 2.8781 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.47, 171.14 APE9-dihe-na 61.62, 132.63 APE8-dihe-in -54.85, 138.82 APE8-rot-in 289.24 APE67-dihe-in -64.78, -22.47 -45.65, -46.11 APE12-dist-in 12.9693 APE11-dist-in 10.8203 APE10-dist-in 6.3285 APE9-dist-in 3.451 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 28 28 0 [[39, 323]] 1.0 AF-Q15131-K3 CMGC_CDK10_HUMAN CMGC 1.2e-77 267.1 1.0 301.0 301.0 180 181 182 184 186 68 86 90 160 162 161 163.0 221 208 203 202 201 200 199 198 197 118 Cyclin-dependent kinase 10

CMGC_CDK10 (Cyclin-dependent kinase 10)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15131-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CDK10 CDK10_HUMAN AF-Q15131-K1A Q15131 31 331 360.0 No_ligand No_ligand Active DFGin 6.8191 14.585 BLAminus -134.17, 178.47 59.03, 71.87 -85.25, 14.73 282.8, 72.74 -59.17, -29.64 in-in in 8.9422 Saltbr-in 2.7319 HRD-in -72.11, -46.66 62.07, 11.62 in-in-in SNCiii in-in ActLoopNT-in 2.9529 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.42, 169.37 APE9-dihe-na 63.7, 130.69 APE8-dihe-in -54.65, 137.66 APE8-rot-in 299.7 APE67-dihe-in -67.0, -22.85 -48.01, -43.94 APE12-dist-in 12.9959 APE11-dist-in 11.1815 APE10-dist-in 6.5459 APE9-dist-in 3.2391 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 28 28 0 [[39, 323]] 1.0 AF-Q15131-K1 Homo sapiens CMGC_CDK10_HUMAN CMGC 1.2e-77 267.1 1.0 301.0 301.0 180 181 182 184 186 68 86 90 160 162 161 163.0 221 208 203 202 201 200 199 198 197 118 Cyclin-dependent kinase 10
CDK10 CDK10_HUMAN AF-Q15131-K3A Q15131 31 331 360.0 No_ligand No_ligand Active DFGin 6.6963 14.7927 BLAminus -131.02, -178.74 61.85, 65.75 -79.68, 11.21 285.29, 77.94 -59.95, -29.89 in-in in 8.8551 Saltbr-in 2.7096 HRD-in -78.08, -43.62 64.02, 9.06 in-in-in SNCiii in-in ActLoopNT-in 2.8781 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.47, 171.14 APE9-dihe-na 61.62, 132.63 APE8-dihe-in -54.85, 138.82 APE8-rot-in 289.24 APE67-dihe-in -64.78, -22.47 -45.65, -46.11 APE12-dist-in 12.9693 APE11-dist-in 10.8203 APE10-dist-in 6.3285 APE9-dist-in 3.451 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 28 28 0 [[39, 323]] 1.0 AF-Q15131-K3 Homo sapiens CMGC_CDK10_HUMAN CMGC 1.2e-77 267.1 1.0 301.0 301.0 180 181 182 184 186 68 86 90 160 162 161 163.0 221 208 203 202 201 200 199 198 197 118 Cyclin-dependent kinase 10

CMGC_CDK10 (Cyclin-dependent kinase 10)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name