CAMK_CAMK2D (Calcium/calmodulin-dependent protein kinase type II subunit delta)

Total number of chains: 14
Active chains: 11
Family: CAMK
Uniprot: KCC2D_HUMAN
Kinase Domain Residues: 14 - 272
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 100.0% AF-Q13557-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q13557-K1A 6 280 499.0 No_ligand No_ligand Active DFGin 6.47 14.236 BLAminus -122.26, 176.5 50.79, 79.83 -85.93, 18.86 290.58, 80.69 -60.01, -28.02 in-in in 8.878 Saltbr-in 2.705 HRD-in -73.19, -46.14 66.59, -7.7 in-in-in SNCiii in-in ActLoopNT-in 2.977 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.85, 148.66 APE9-dihe-na 124.57, 167.11 APE8-dihe-in -82.49, 133.61 APE8-rot-in 301.15 APE67-dihe-in -70.6, -10.99 -46.16, -50.3 APE12-dist-in 10.441 APE11-dist-in 11.599 APE10-dist-in 5.843 APE9-dist-in 3.48 None None None AF2 -1.0 1.0 1.0 A 275 275 0 0 0 0 [[14, 272]] 1.0 AF-Q13557-K1 CAMK_CAMK2D_HUMAN CAMK 2.3e-97 331.3 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
AF-Q13557-K3A 6 280 499.0 No_ligand No_ligand Active DFGin 6.367 14.431 BLAminus -125.77, -173.51 57.56, 49.81 -66.58, 13.13 291.86, 87.7 -61.89, -25.38 in-in in 8.978 Saltbr-in 2.694 HRD-in -76.63, -46.39 66.7, -1.66 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.39, 148.47 APE9-dihe-na 123.48, 170.64 APE8-dihe-in -87.53, 133.84 APE8-rot-in 297.22 APE67-dihe-in -70.58, -13.09 -45.92, -50.3 APE12-dist-in 10.444 APE11-dist-in 11.437 APE10-dist-in 5.73 APE9-dist-in 3.228 None None None AF2 -1.0 1.0 1.0 A 275 275 0 0 0 0 [[14, 272]] 1.0 AF-Q13557-K3 CAMK_CAMK2D_HUMAN CAMK 2.3e-97 331.3 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
8USOB 6 475 498.0 No_ligand No_ligand Active DFGin 6.806 15.016 BLAminus -127.5, 163.6 65.94, 89.59 -102.38, 32.29 288.13, 79.86 -71.59, -19.82 in-in in 8.59 Saltbr-in 2.639 HRD-in -71.3, -50.05 77.65, -5.71 in-in-in SNCiii in-in ActLoopNT-in 3.034 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.54, 150.5 APE9-dihe-na 136.44, -170.02 APE8-dihe-in -111.38, 131.33 APE8-rot-in 304.76 APE67-dihe-in -65.19, -20.1 -48.22, -47.04 APE12-dist-in 10.184 APE11-dist-in 11.895 APE10-dist-in 6.075 APE9-dist-in 3.619 D364C None None XRAY 2.3 0.185 0.213 B 450 436 0 0 0 0 [[14, 272]] 1.0 8uso CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
9BLHA 11 301 499.0 6ZZ:400 Type1 Active DFGin 6.557 14.798 BLAminus -126.09, 171.4 53.95, 91.02 -97.64, 24.97 286.97, 77.72 -61.75, -25.83 in-in in 8.382 Saltbr-in 2.685 HRD-in -69.34, -46.51 75.56, -3.98 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.43, 148.15 APE9-dihe-na 136.6, -162.07 APE8-dihe-in -117.16, 133.77 APE8-rot-in 302.83 APE67-dihe-in -65.71, -19.8 -50.02, -46.22 APE12-dist-in 10.25 APE11-dist-in 11.703 APE10-dist-in 5.909 APE9-dist-in 3.695 None None None XRAY 2.35 0.201 0.251 A 300 291 0 0 0 0 [[14, 272]] 1.0 9blh CAMK_CAMK2D_HUMAN CAMK 3.1e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
9BLHB 11 298 499.0 6ZZ:401 Type1 Active DFGin 6.707 14.726 BLAminus -132.5, 166.89 59.11, 88.28 -98.43, 27.58 287.41, 83.03 -66.65, -16.38 in-in in 8.373 Saltbr-in 2.905 HRD-in -69.19, -48.82 76.63, -7.07 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.98, 154.85 APE9-dihe-na 124.25, -172.4 APE8-dihe-in -108.0, 132.6 APE8-rot-in 299.23 APE67-dihe-inflip 89.48, -27.26 -55.4, 149.02 APE12-dist-in 10.146 APE11-dist-in 11.85 APE10-dist-in 5.995 APE9-dist-in 3.583 None None None XRAY 2.35 0.201 0.251 B 300 288 0 0 0 0 [[14, 272]] 1.0 9blh CAMK_CAMK2D_HUMAN CAMK 3.1e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
2VN9A 10 309 499.0 GVD:61314 Type1 Active DFGin 6.59 14.614 BLAminus -124.96, 171.71 55.2, 92.42 -101.83, 28.41 288.28, 77.94 -66.41, -20.24 in-in in 9.242 Saltbr-in 2.843 HRD-in -68.47, -47.2 70.33, 2.64 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.47, 140.91 APE9-dihe-na 137.94, -158.39 APE8-dihe-in -117.81, 127.62 APE8-rot-in 304.33 APE67-dihe-in -59.63, -25.55 -44.23, -52.64 APE12-dist-in 10.261 APE11-dist-in 11.912 APE10-dist-in 6.197 APE9-dist-in 3.798 None None None XRAY 2.3 0.213 0.248 A 301 300 0 0 0 0 [[14, 272]] 1.0 2vn9 CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
2VN9B 10 309 499.0 GVD:61310 Type1 Active DFGin 6.551 14.602 BLAminus -127.37, 171.91 57.38, 92.45 -101.92, 22.76 286.58, 76.44 -61.0, -20.5 in-in in 9.266 Saltbr-in 2.869 HRD-in -69.29, -46.65 68.24, 3.32 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.29, 141.49 APE9-dihe-na 142.44, -161.34 APE8-dihe-in -114.21, 127.94 APE8-rot-in 302.01 APE67-dihe-in -63.28, -20.34 -43.86, -50.83 APE12-dist-in 10.34 APE11-dist-in 11.874 APE10-dist-in 6.184 APE9-dist-in 3.738 None None None XRAY 2.3 0.213 0.248 B 301 300 0 0 0 0 [[14, 272]] 1.0 2vn9 CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
5VLOA 8 300 499.0 9EJ:401 Type1 Active DFGin 6.706 13.878 BLAminus -130.05, 160.81 64.78, 109.07 -117.58, 29.14 292.75, 86.52 -65.37, -22.87 in-in in 8.775 Saltbr-in 2.449 HRD-in -65.49, -44.36 73.72, -7.68 in-in-in SNCiii in-in ActLoopNT-in 3.01 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -170.47, 145.71 APE9-dihe-na 128.02, 178.51 APE8-dihe-in -112.02, 134.64 APE8-rot-in 309.42 APE67-dihe-in -64.14, -15.28 -42.07, -53.64 APE12-dist-in 10.859 APE11-dist-in 11.037 APE10-dist-in 5.888 APE9-dist-in 3.642 None None None XRAY 2.05 0.184 0.226 A 302 290 3 0 0 0 [[14, 272]] 1.0 5vlo CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
5VLOB 7 299 499.0 9EJ:401 Type1 Active DFGin 6.484 13.904 BLAminus -134.01, 166.26 64.06, 99.6 -109.74, 31.17 294.26, 89.58 -69.03, -23.87 in-in in 8.824 Saltbr-in 2.639 HRD-in -72.23, -47.02 74.68, -1.49 in-in-in SNCiii in-in ActLoopNT-in 2.984 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.65, 146.65 APE9-dihe-na 120.86, -178.91 APE8-dihe-in -104.42, 135.12 APE8-rot-in 295.71 APE67-dihe-in -65.09, -10.9 -46.09, -51.75 APE12-dist-in 10.632 APE11-dist-in 10.897 APE10-dist-in 5.457 APE9-dist-in 3.347 None None None XRAY 2.05 0.184 0.226 B 302 293 0 0 0 0 [[14, 272]] 1.0 5vlo CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
6AYWA 8 300 499.0 C2V:401 Type1 Active DFGin 6.798 14.013 BLAminus -129.66, 162.48 66.98, 94.93 -102.18, 23.06 289.39, 86.24 -60.21, -25.31 in-in in 8.729 Saltbr-in 2.618 HRD-in -76.7, -45.04 76.44, -3.66 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.63, 143.06 APE9-dihe-na 136.95, 172.55 APE8-dihe-in -110.09, 132.94 APE8-rot-in 297.48 APE67-dihe-in -62.77, -18.19 -52.65, -46.68 APE12-dist-in 10.672 APE11-dist-in 11.217 APE10-dist-in 5.815 APE9-dist-in 3.585 None None None XRAY 2.05 0.202 0.267 A 302 293 0 0 0 0 [[14, 272]] 1.0 6ayw CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
6AYWB 7 299 499.0 C2V:402 Type1 Active DFGin 6.584 13.97 BLAminus -126.53, 171.85 60.28, 89.59 -97.82, 25.08 291.27, 84.52 -59.0, -26.52 in-in in 8.56 Saltbr-in 2.653 HRD-in -72.96, -48.66 76.86, -6.98 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.64, 142.07 APE9-dihe-na 121.32, -174.92 APE8-dihe-in -105.07, 134.99 APE8-rot-in 288.9 APE67-dihe-in -65.78, -11.98 -46.42, -51.9 APE12-dist-in 10.672 APE11-dist-in 11.089 APE10-dist-in 5.676 APE9-dist-in 3.603 None None None XRAY 2.05 0.202 0.267 B 302 293 0 0 0 0 [[14, 272]] 1.0 6ayw CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
8USOA 10 475 498.0 No_ligand No_ligand Inactive DFGin 6.512 16.098 BLAminus -136.26, 159.95 64.47, 87.76 -96.74, 31.43 292.8, 75.05 -67.19, -20.65 out-out out 10.054 Saltbr-out 5.978 HRD-in -75.31, -45.72 72.72, -2.93 out-in-in SNCoii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.97, 151.54 APE9-dihe-na 132.14, -174.67 APE8-dihe-in -107.21, 128.67 APE8-rot-in 301.72 APE67-dihe-in -62.05, -13.4 -43.38, -52.87 APE12-dist-in 10.382 APE11-dist-in 11.932 APE10-dist-in 6.137 APE9-dist-in 3.659 D364C None None XRAY 2.3 0.185 0.213 A 450 438 0 0 0 0 [[14, 272]] 1.0 8uso CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
8USOC 15 477 498.0 No_ligand No_ligand Inactive DFGin 6.392 15.899 BLAminus -132.96, 157.74 69.51, 85.68 -95.48, 31.72 292.01, 74.47 -66.74, -19.8 out-out out 10.092 Saltbr-out 4.643 HRD-in -70.03, -48.41 77.24, -7.38 out-in-in SNCoii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.06, 149.84 APE9-dihe-na 137.29, -169.87 APE8-dihe-in -107.54, 129.34 APE8-rot-in 300.25 APE67-dihe-in -59.42, -18.82 -44.56, -53.75 APE12-dist-in 10.476 APE11-dist-in 12.078 APE10-dist-in 6.277 APE9-dist-in 3.802 D364C None None XRAY 2.3 0.185 0.213 C 450 433 3 0 0 0 [[14, 272]] 1.0 8uso CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
2WELA 10 316 499.0 K88:60600 Type1 Inactive DFGin 6.39 15.596 BLAminus -134.98, -174.35 62.47, 61.94 -83.32, 16.97 282.72, 80.25 -61.1, -22.15 out-out out 10.333 Saltbr-out 4.742 HRD-in -72.69, -42.0 70.57, -3.91 out-in-in SNCoii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.65, 142.89 APE9-dihe-na 143.64, -158.53 APE8-dihe-in -120.46, 127.42 APE8-rot-in 303.42 APE67-dihe-in -67.04, -16.67 -40.87, -53.15 APE12-dist-in 10.185 APE11-dist-in 11.674 APE10-dist-in 5.957 APE9-dist-in 3.628 None None None XRAY 1.9 0.161 0.199 A 327 303 0 0 0 0 [[14, 272]] 1.0 2wel CAMK_CAMK2D_HUMAN CAMK 4.2e-97 330.6 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta

CAMK_CAMK2D (Calcium/calmodulin-dependent protein kinase type II subunit delta)

Total number of chains: 18
Active chains: 15
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 18 100.0% AF-Q13557-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KCC2D_HUMAN AF-Q13557-K1A Q13557 6 280 499.0 No_ligand No_ligand Active DFGin 6.47 14.236 BLAminus -122.26, 176.5 50.79, 79.83 -85.93, 18.86 290.58, 80.69 -60.01, -28.02 in-in in 8.878 Saltbr-in 2.705 HRD-in -73.19, -46.14 66.59, -7.7 in-in-in SNCiii in-in ActLoopNT-in 2.977 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.85, 148.66 APE9-dihe-na 124.57, 167.11 APE8-dihe-in -82.49, 133.61 APE8-rot-in 301.15 APE67-dihe-in -70.6, -10.99 -46.16, -50.3 APE12-dist-in 10.441 APE11-dist-in 11.599 APE10-dist-in 5.843 APE9-dist-in 3.48 None None None AF2 -1.0 1.0 1.0 A 275 275 0 0 0 0 [[14, 272]] 1.0 AF-Q13557-K1 Homo sapiens CAMK_CAMK2D_HUMAN CAMK 2.3e-97 331.3 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN AF-Q13557-K3A Q13557 6 280 499.0 No_ligand No_ligand Active DFGin 6.367 14.431 BLAminus -125.77, -173.51 57.56, 49.81 -66.58, 13.13 291.86, 87.7 -61.89, -25.38 in-in in 8.978 Saltbr-in 2.694 HRD-in -76.63, -46.39 66.7, -1.66 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.39, 148.47 APE9-dihe-na 123.48, 170.64 APE8-dihe-in -87.53, 133.84 APE8-rot-in 297.22 APE67-dihe-in -70.58, -13.09 -45.92, -50.3 APE12-dist-in 10.444 APE11-dist-in 11.437 APE10-dist-in 5.73 APE9-dist-in 3.228 None None None AF2 -1.0 1.0 1.0 A 275 275 0 0 0 0 [[14, 272]] 1.0 AF-Q13557-K3 Homo sapiens CAMK_CAMK2D_HUMAN CAMK 2.3e-97 331.3 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
D6R938_HUMAN 8USOB D6R938 6 475 498.0 No_ligand No_ligand Active DFGin 6.806 15.016 BLAminus -127.5, 163.6 65.94, 89.59 -102.38, 32.29 288.13, 79.86 -71.59, -19.82 in-in in 8.59 Saltbr-in 2.639 HRD-in -71.3, -50.05 77.65, -5.71 in-in-in SNCiii in-in ActLoopNT-in 3.034 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.54, 150.5 APE9-dihe-na 136.44, -170.02 APE8-dihe-in -111.38, 131.33 APE8-rot-in 304.76 APE67-dihe-in -65.19, -20.1 -48.22, -47.04 APE12-dist-in 10.184 APE11-dist-in 11.895 APE10-dist-in 6.075 APE9-dist-in 3.619 D364C None None XRAY 2.3 0.185 0.213 B 450 436 0 0 0 0 [[14, 272]] 1.0 8uso Homo sapiens CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
KCC2D_HUMAN 9BLHA Q13557 11 301 499.0 6ZZ:400 Type1 Active DFGin 6.557 14.798 BLAminus -126.09, 171.4 53.95, 91.02 -97.64, 24.97 286.97, 77.72 -61.75, -25.83 in-in in 8.382 Saltbr-in 2.685 HRD-in -69.34, -46.51 75.56, -3.98 in-in-in SNCiii in-in ActLoopNT-in 2.928 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.43, 148.15 APE9-dihe-na 136.6, -162.07 APE8-dihe-in -117.16, 133.77 APE8-rot-in 302.83 APE67-dihe-in -65.71, -19.8 -50.02, -46.22 APE12-dist-in 10.25 APE11-dist-in 11.703 APE10-dist-in 5.909 APE9-dist-in 3.695 None None None XRAY 2.35 0.201 0.251 A 300 291 0 0 0 0 [[14, 272]] 1.0 9blh Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.1e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 9BLHB Q13557 11 298 499.0 6ZZ:401 Type1 Active DFGin 6.707 14.726 BLAminus -132.5, 166.89 59.11, 88.28 -98.43, 27.58 287.41, 83.03 -66.65, -16.38 in-in in 8.373 Saltbr-in 2.905 HRD-in -69.19, -48.82 76.63, -7.07 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.98, 154.85 APE9-dihe-na 124.25, -172.4 APE8-dihe-in -108.0, 132.6 APE8-rot-in 299.23 APE67-dihe-inflip 89.48, -27.26 -55.4, 149.02 APE12-dist-in 10.146 APE11-dist-in 11.85 APE10-dist-in 5.995 APE9-dist-in 3.583 None None None XRAY 2.35 0.201 0.251 B 300 288 0 0 0 0 [[14, 272]] 1.0 9blh Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.1e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 2VN9A Q13557 10 309 499.0 GVD:61314 Type1 Active DFGin 6.59 14.614 BLAminus -124.96, 171.71 55.2, 92.42 -101.83, 28.41 288.28, 77.94 -66.41, -20.24 in-in in 9.242 Saltbr-in 2.843 HRD-in -68.47, -47.2 70.33, 2.64 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.47, 140.91 APE9-dihe-na 137.94, -158.39 APE8-dihe-in -117.81, 127.62 APE8-rot-in 304.33 APE67-dihe-in -59.63, -25.55 -44.23, -52.64 APE12-dist-in 10.261 APE11-dist-in 11.912 APE10-dist-in 6.197 APE9-dist-in 3.798 None None None XRAY 2.3 0.213 0.248 A 301 300 0 0 0 0 [[14, 272]] 1.0 2vn9 Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 2VN9B Q13557 10 309 499.0 GVD:61310 Type1 Active DFGin 6.551 14.602 BLAminus -127.37, 171.91 57.38, 92.45 -101.92, 22.76 286.58, 76.44 -61.0, -20.5 in-in in 9.266 Saltbr-in 2.869 HRD-in -69.29, -46.65 68.24, 3.32 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.29, 141.49 APE9-dihe-na 142.44, -161.34 APE8-dihe-in -114.21, 127.94 APE8-rot-in 302.01 APE67-dihe-in -63.28, -20.34 -43.86, -50.83 APE12-dist-in 10.34 APE11-dist-in 11.874 APE10-dist-in 6.184 APE9-dist-in 3.738 None None None XRAY 2.3 0.213 0.248 B 301 300 0 0 0 0 [[14, 272]] 1.0 2vn9 Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.9 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 5VLOA Q13557 8 300 499.0 9EJ:401 Type1 Active DFGin 6.706 13.878 BLAminus -130.05, 160.81 64.78, 109.07 -117.58, 29.14 292.75, 86.52 -65.37, -22.87 in-in in 8.775 Saltbr-in 2.449 HRD-in -65.49, -44.36 73.72, -7.68 in-in-in SNCiii in-in ActLoopNT-in 3.01 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -170.47, 145.71 APE9-dihe-na 128.02, 178.51 APE8-dihe-in -112.02, 134.64 APE8-rot-in 309.42 APE67-dihe-in -64.14, -15.28 -42.07, -53.64 APE12-dist-in 10.859 APE11-dist-in 11.037 APE10-dist-in 5.888 APE9-dist-in 3.642 None None None XRAY 2.05 0.184 0.226 A 302 290 3 0 0 0 [[14, 272]] 1.0 5vlo Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 5VLOB Q13557 7 299 499.0 9EJ:401 Type1 Active DFGin 6.484 13.904 BLAminus -134.01, 166.26 64.06, 99.6 -109.74, 31.17 294.26, 89.58 -69.03, -23.87 in-in in 8.824 Saltbr-in 2.639 HRD-in -72.23, -47.02 74.68, -1.49 in-in-in SNCiii in-in ActLoopNT-in 2.984 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.65, 146.65 APE9-dihe-na 120.86, -178.91 APE8-dihe-in -104.42, 135.12 APE8-rot-in 295.71 APE67-dihe-in -65.09, -10.9 -46.09, -51.75 APE12-dist-in 10.632 APE11-dist-in 10.897 APE10-dist-in 5.457 APE9-dist-in 3.347 None None None XRAY 2.05 0.184 0.226 B 302 293 0 0 0 0 [[14, 272]] 1.0 5vlo Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 6AYWA Q13557 8 300 499.0 C2V:401 Type1 Active DFGin 6.798 14.013 BLAminus -129.66, 162.48 66.98, 94.93 -102.18, 23.06 289.39, 86.24 -60.21, -25.31 in-in in 8.729 Saltbr-in 2.618 HRD-in -76.7, -45.04 76.44, -3.66 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.63, 143.06 APE9-dihe-na 136.95, 172.55 APE8-dihe-in -110.09, 132.94 APE8-rot-in 297.48 APE67-dihe-in -62.77, -18.19 -52.65, -46.68 APE12-dist-in 10.672 APE11-dist-in 11.217 APE10-dist-in 5.815 APE9-dist-in 3.585 None None None XRAY 2.05 0.202 0.267 A 302 293 0 0 0 0 [[14, 272]] 1.0 6ayw Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_HUMAN 6AYWB Q13557 7 299 499.0 C2V:402 Type1 Active DFGin 6.584 13.97 BLAminus -126.53, 171.85 60.28, 89.59 -97.82, 25.08 291.27, 84.52 -59.0, -26.52 in-in in 8.56 Saltbr-in 2.653 HRD-in -72.96, -48.66 76.86, -6.98 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -166.64, 142.07 APE9-dihe-na 121.32, -174.92 APE8-dihe-in -105.07, 134.99 APE8-rot-in 288.9 APE67-dihe-in -65.78, -11.98 -46.42, -51.9 APE12-dist-in 10.672 APE11-dist-in 11.089 APE10-dist-in 5.676 APE9-dist-in 3.603 None None None XRAY 2.05 0.202 0.267 B 302 293 0 0 0 0 [[14, 272]] 1.0 6ayw Homo sapiens CAMK_CAMK2D_HUMAN CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
D6R938_HUMAN 8USOA D6R938 10 475 498.0 No_ligand No_ligand Inactive DFGin 6.512 16.098 BLAminus -136.26, 159.95 64.47, 87.76 -96.74, 31.43 292.8, 75.05 -67.19, -20.65 out-out out 10.054 Saltbr-out 5.978 HRD-in -75.31, -45.72 72.72, -2.93 out-in-in SNCoii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.97, 151.54 APE9-dihe-na 132.14, -174.67 APE8-dihe-in -107.21, 128.67 APE8-rot-in 301.72 APE67-dihe-in -62.05, -13.4 -43.38, -52.87 APE12-dist-in 10.382 APE11-dist-in 11.932 APE10-dist-in 6.137 APE9-dist-in 3.659 D364C None None XRAY 2.3 0.185 0.213 A 450 438 0 0 0 0 [[14, 272]] 1.0 8uso Homo sapiens CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
D6R938_HUMAN 8USOC D6R938 15 477 498.0 No_ligand No_ligand Inactive DFGin 6.392 15.899 BLAminus -132.96, 157.74 69.51, 85.68 -95.48, 31.72 292.01, 74.47 -66.74, -19.8 out-out out 10.092 Saltbr-out 4.643 HRD-in -70.03, -48.41 77.24, -7.38 out-in-in SNCoii in-in ActLoopNT-in 2.949 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.06, 149.84 APE9-dihe-na 137.29, -169.87 APE8-dihe-in -107.54, 129.34 APE8-rot-in 300.25 APE67-dihe-in -59.42, -18.82 -44.56, -53.75 APE12-dist-in 10.476 APE11-dist-in 12.078 APE10-dist-in 6.277 APE9-dist-in 3.802 D364C None None XRAY 2.3 0.185 0.213 C 450 433 3 0 0 0 [[14, 272]] 1.0 8uso Homo sapiens CAMK_CAMK2D_HUMAN CAMK 1.1e-96 329.4 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 calcium/calmodulin-dependent protein kinase
KCC2D_HUMAN 2WELA Q13557 10 316 499.0 K88:60600 Type1 Inactive DFGin 6.39 15.596 BLAminus -134.98, -174.35 62.47, 61.94 -83.32, 16.97 282.72, 80.25 -61.1, -22.15 out-out out 10.333 Saltbr-out 4.742 HRD-in -72.69, -42.0 70.57, -3.91 out-in-in SNCoii in-in ActLoopNT-in 2.913 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.65, 142.89 APE9-dihe-na 143.64, -158.53 APE8-dihe-in -120.46, 127.42 APE8-rot-in 303.42 APE67-dihe-in -67.04, -16.67 -40.87, -53.15 APE12-dist-in 10.185 APE11-dist-in 11.674 APE10-dist-in 5.957 APE9-dist-in 3.628 None None None XRAY 1.9 0.161 0.199 A 327 303 0 0 0 0 [[14, 272]] 1.0 2wel Homo sapiens CAMK_CAMK2D_HUMAN CAMK 4.2e-97 330.6 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABA Q6PHZ2 11 300 499.0 D0S:60401 Type1 Active DFGin 6.434 13.672 BLAminus -128.46, 167.61 64.72, 89.3 -97.86, 28.37 292.6, 79.67 -64.04, -23.93 in-in in 8.966 Saltbr-in 2.693 HRD-in -73.05, -47.45 75.62, -4.08 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.58, 152.94 APE9-dihe-na 125.13, -172.88 APE8-dihe-in -107.35, 130.65 APE8-rot-in 302.77 APE67-dihe-in -57.0, -18.24 -42.76, -53.6 APE12-dist-in 10.348 APE11-dist-in 11.395 APE10-dist-in 5.685 APE9-dist-in 3.591 None None None XRAY 1.91 0.191 0.253 A 302 290 0 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABB Q6PHZ2 13 301 499.0 D0S:60401 Type1 Active DFGin 6.535 13.925 BLAminus -124.03, 170.27 57.01, 92.88 -98.55, 29.41 286.57, 76.55 -64.39, -26.12 in-in in 8.788 Saltbr-in 2.695 HRD-in -68.63, -46.94 68.55, -1.74 in-in-in SNCiii in-in ActLoopNT-in 2.994 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.44, 140.93 APE9-dihe-na 132.51, -177.47 APE8-dihe-in -104.73, 132.03 APE8-rot-in 302.85 APE67-dihe-in -65.71, -16.01 -44.83, -47.92 APE12-dist-in 10.745 APE11-dist-in 11.115 APE10-dist-in 5.541 APE9-dist-in 3.6 None None None XRAY 1.91 0.191 0.253 B 302 285 4 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABC Q6PHZ2 13 300 499.0 D0S:60401 Type1 Active DFGin 6.395 13.775 BLAminus -129.26, 163.64 65.29, 99.74 -105.31, 26.69 290.73, 78.05 -63.58, -23.08 in-in in 9.12 Saltbr-in 2.382 HRD-in -68.77, -48.53 77.55, -12.58 in-in-in SNCiii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.57, 154.12 APE9-dihe-na 128.46, 172.92 APE8-dihe-in -92.7, 129.68 APE8-rot-in 287.18 APE67-dihe-in -70.2, -9.32 -41.62, -51.68 APE12-dist-in 10.625 APE11-dist-in 11.535 APE10-dist-in 5.779 APE9-dist-in 3.737 None None None XRAY 1.91 0.191 0.253 C 302 284 4 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABD Q6PHZ2 9 300 499.0 D0S:60401 Type1 Active DFGin 6.518 13.99 BLAminus -125.21, 168.26 61.35, 91.2 -99.43, 29.39 287.39, 74.4 -63.27, -28.43 in-in in 8.779 Saltbr-in 2.464 HRD-in -75.48, -45.49 74.44, -3.14 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.25, 152.93 APE9-dihe-na 120.97, -176.88 APE8-dihe-in -104.52, 129.85 APE8-rot-in 296.8 APE67-dihe-in -66.8, -16.78 -44.92, -46.52 APE12-dist-in 10.756 APE11-dist-in 11.216 APE10-dist-in 5.675 APE9-dist-in 3.66 None None None XRAY 1.91 0.191 0.253 D 302 292 0 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta

CAMK_CAMK2D (Calcium/calmodulin-dependent protein kinase type II subunit delta)

Total number of chains: 4
Active chains: 4
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6BABA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KCC2D_MOUSE 6BABA Q6PHZ2 11 300 499.0 D0S:60401 Type1 Active DFGin 6.434 13.672 BLAminus -128.46, 167.61 64.72, 89.3 -97.86, 28.37 292.6, 79.67 -64.04, -23.93 in-in in 8.966 Saltbr-in 2.693 HRD-in -73.05, -47.45 75.62, -4.08 in-in-in SNCiii in-in ActLoopNT-in 2.869 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.58, 152.94 APE9-dihe-na 125.13, -172.88 APE8-dihe-in -107.35, 130.65 APE8-rot-in 302.77 APE67-dihe-in -57.0, -18.24 -42.76, -53.6 APE12-dist-in 10.348 APE11-dist-in 11.395 APE10-dist-in 5.685 APE9-dist-in 3.591 None None None XRAY 1.91 0.191 0.253 A 302 290 0 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABB Q6PHZ2 13 301 499.0 D0S:60401 Type1 Active DFGin 6.535 13.925 BLAminus -124.03, 170.27 57.01, 92.88 -98.55, 29.41 286.57, 76.55 -64.39, -26.12 in-in in 8.788 Saltbr-in 2.695 HRD-in -68.63, -46.94 68.55, -1.74 in-in-in SNCiii in-in ActLoopNT-in 2.994 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.44, 140.93 APE9-dihe-na 132.51, -177.47 APE8-dihe-in -104.73, 132.03 APE8-rot-in 302.85 APE67-dihe-in -65.71, -16.01 -44.83, -47.92 APE12-dist-in 10.745 APE11-dist-in 11.115 APE10-dist-in 5.541 APE9-dist-in 3.6 None None None XRAY 1.91 0.191 0.253 B 302 285 4 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABC Q6PHZ2 13 300 499.0 D0S:60401 Type1 Active DFGin 6.395 13.775 BLAminus -129.26, 163.64 65.29, 99.74 -105.31, 26.69 290.73, 78.05 -63.58, -23.08 in-in in 9.12 Saltbr-in 2.382 HRD-in -68.77, -48.53 77.55, -12.58 in-in-in SNCiii in-in ActLoopNT-in 2.906 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.57, 154.12 APE9-dihe-na 128.46, 172.92 APE8-dihe-in -92.7, 129.68 APE8-rot-in 287.18 APE67-dihe-in -70.2, -9.32 -41.62, -51.68 APE12-dist-in 10.625 APE11-dist-in 11.535 APE10-dist-in 5.779 APE9-dist-in 3.737 None None None XRAY 1.91 0.191 0.253 C 302 284 4 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta
KCC2D_MOUSE 6BABD Q6PHZ2 9 300 499.0 D0S:60401 Type1 Active DFGin 6.518 13.99 BLAminus -125.21, 168.26 61.35, 91.2 -99.43, 29.39 287.39, 74.4 -63.27, -28.43 in-in in 8.779 Saltbr-in 2.464 HRD-in -75.48, -45.49 74.44, -3.14 in-in-in SNCiii in-in ActLoopNT-in 2.861 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -162.25, 152.93 APE9-dihe-na 120.97, -176.88 APE8-dihe-in -104.52, 129.85 APE8-rot-in 296.8 APE67-dihe-in -66.8, -16.78 -44.92, -46.52 APE12-dist-in 10.756 APE11-dist-in 11.216 APE10-dist-in 5.675 APE9-dist-in 3.66 None None None XRAY 1.91 0.191 0.253 D 302 292 0 0 0 0 [[14, 272]] 1.0 6bab Mus musculus CAMK_CAMK2D_MOUSE CAMK 3.2e-97 330.8 1 256 256 156 157 158 160 162 43 61 65 133 135 134 136 196 184 179 178 177 176 175 174 173 91 Calcium/calmodulin-dependent protein kinase type II subunit delta