TKL_ACVR1C (Activin receptor type-1C)

Total number of chains: 2
Active chains: 2
Uniprot: ACV1C_HUMAN
Kinase Domain Residues: 195 - 484
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q8NER5-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q8NER5-K1A 187 492 493.0 No_ligand No_ligand Active DFGin 6.516 13.354 BLAminus -122.82, 178.42 56.17, 64.64 -81.06, 15.55 297.47, 178.39 -62.16, -22.48 in-in in 8.313 Saltbr-in 2.709 HRD-in -79.4, -38.68 68.03, -19.63 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.81, 171.72 APE9-dihe-na 97.39, -177.81 APE8-dihe-in -81.69, 116.95 APE8-rot-in 304.88 APE67-dihe-in -61.84, -26.17 -48.47, -41.38 APE12-dist-in 11.004 APE11-dist-in 11.831 APE10-dist-in 6.115 APE9-dist-in 3.981 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[195, 484]] 1.0 AF-Q8NER5-K1 TKL_ACVR1C_HUMAN TKL 6.1e-82 281.0 3 266 264 340 341 342 344 346 222 235 239 320 322 321 323 390 372 367 366 365 364 363 362 361 271 Activin receptor type-1C
AF-Q8NER5-K3A 187 492 493.0 No_ligand No_ligand Active DFGin 6.366 12.519 BLAminus -129.07, -179.17 60.47, 53.28 -74.02, 8.58 298.95, 178.92 -64.27, -20.36 in-in in 8.225 Saltbr-in 2.738 HRD-in -77.53, -39.33 67.66, -14.88 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.12, 164.02 APE9-dihe-na 115.58, 166.65 APE8-dihe-in -85.76, 117.71 APE8-rot-in 301.88 APE67-dihe-in -62.4, -23.07 -40.3, -47.42 APE12-dist-in 10.42 APE11-dist-in 11.237 APE10-dist-in 5.519 APE9-dist-in 3.636 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[195, 484]] 1.0 AF-Q8NER5-K3 TKL_ACVR1C_HUMAN TKL 6.1e-82 281.0 3 266 264 340 341 342 344 346 222 235 239 320 322 321 323 390 372 367 366 365 364 363 362 361 271 Activin receptor type-1C

TKL_ACVR1C (Activin receptor type-1C)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q8NER5-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
ACV1C_HUMAN AF-Q8NER5-K1A Q8NER5 187 492 493.0 No_ligand No_ligand Active DFGin 6.516 13.354 BLAminus -122.82, 178.42 56.17, 64.64 -81.06, 15.55 297.47, 178.39 -62.16, -22.48 in-in in 8.313 Saltbr-in 2.709 HRD-in -79.4, -38.68 68.03, -19.63 in-in-in SNCiii in-in ActLoopNT-in 2.879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.81, 171.72 APE9-dihe-na 97.39, -177.81 APE8-dihe-in -81.69, 116.95 APE8-rot-in 304.88 APE67-dihe-in -61.84, -26.17 -48.47, -41.38 APE12-dist-in 11.004 APE11-dist-in 11.831 APE10-dist-in 6.115 APE9-dist-in 3.981 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[195, 484]] 1.0 AF-Q8NER5-K1 Homo sapiens TKL_ACVR1C_HUMAN TKL 6.1e-82 281.0 3 266 264 340 341 342 344 346 222 235 239 320 322 321 323 390 372 367 366 365 364 363 362 361 271 Activin receptor type-1C
ACV1C_HUMAN AF-Q8NER5-K3A Q8NER5 187 492 493.0 No_ligand No_ligand Active DFGin 6.366 12.519 BLAminus -129.07, -179.17 60.47, 53.28 -74.02, 8.58 298.95, 178.92 -64.27, -20.36 in-in in 8.225 Saltbr-in 2.738 HRD-in -77.53, -39.33 67.66, -14.88 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.12, 164.02 APE9-dihe-na 115.58, 166.65 APE8-dihe-in -85.76, 117.71 APE8-rot-in 301.88 APE67-dihe-in -62.4, -23.07 -40.3, -47.42 APE12-dist-in 10.42 APE11-dist-in 11.237 APE10-dist-in 5.519 APE9-dist-in 3.636 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[195, 484]] 1.0 AF-Q8NER5-K3 Homo sapiens TKL_ACVR1C_HUMAN TKL 6.1e-82 281.0 3 266 264 340 341 342 344 346 222 235 239 320 322 321 323 390 372 367 366 365 364 363 362 361 271 Activin receptor type-1C

TKL_ACVR1C (Activin receptor type-1C)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name